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20 Aug 2021: owners. As a result, they tend to be given a lower relative dose than people are, to reduce the side effects, but this also means it. ... We can then use this information to help improve drug development for people by giving more accurate information on

12 Nov 2021: At Cambridge, our research compliance is regulated by ASPA and is monitored by University staff, including the Named People, such as Named Animal Care and Welfare Officers (NACWOs), and Named Veterinary

13 Sep 2021: sugar control and lose weight, whilst decreasing or blocking the signals that make some people sick after surgery, thereby improving their post-surgical quality of live. ... the gut in a similar way used for the treatment of very overweight people.

18 Jun 2021: In both mice and people, digit tip regrowth depends on how much of the finger or toe is removed. ... makes us confident that any results we get will also be useful for people.

13 Sep 2021: Furthermore, we do not understand how these bacteria spread in the environment and how they infect people. ... Doctors and patients will benefit from this research that will improve the treatment of sick people, especially children and will also reduce

13 Sep 2021: We will also be studying lung cancer. Nearly 45,000 new cases of lung cancer are diagnosed annually and nearly 35,000 people die from the disease in the UK every

18 Jun 2021: This includes developmental disorders such as progeria, an illness where people show signs of ageing and die early. ... It is estimated that 47 million people live with dementia around the world.

19 Aug 2021: Our research using animals has helped drive advances in cancer treatment that are benefiting people with cancer all over the world today. ... Studies of cancer in mice mimic the complex way tumours grow and spread in people with cancer.

13 Sep 2021: With 3.3 billion people at risk of infection and 229 million people infected with malaria every year, resulting in over 409,000 annual deaths (WHO World Malaria report 2020). ... With billions of people at risk of infection, causing substantial disease

13 Sep 2021: people per million. ... This "Pulmonary Arterial Hypertension" (PAH) is usually diagnosed in people between the ages of 20 and 60, affecting more women than men.

19 Aug 2021: Why is it important to undertake this work? As life expectancy increases, there are a growing number of brain diseases affecting people.

13 Sep 2021: research, approaches and techniques regularly with scientists, animal technicians and Named People (in particular Animal Care and Welfare Officers and Veterinary Surgeons) within and outside the institute.

13 Sep 2021: Starting in adolescence, people with mutations in their FBXO7 gene develop a progressive parkinsonism which affects their coordination along with other symptoms.

20 Aug 2021: Who or what will benefit from these outputs, and how? Neurodegenerative disease affects millions of people and animals worldwide.

19 Aug 2021: womb. We hope to identify novel targets for drug intervention to protect people from developing cardiovascular diseases later in life.

13 Sep 2021: There are around 7.6 million people living with heart and circulatory diseases in the UK.

19 Aug 2021: There are already approximately 50 million people worldwide with dementia, and as the general population ages, this has been predicted to increase to 150 million by 2050.

13 Sep 2021: Page 2 of 5. Our research aims to understand how and why mental health disorders occur, and to develop new treatments for people suffering from these disorders.

18 Jun 2021: In addition, if we can develop new treatments for cancer, this will improve people's health-span: their length of healthy life. ... Of course, if people live into dependent old age this may increase societal costs later.

13 Sep 2021: Why is it important to undertake this work? Multiple sclerosis (MS) is a lifelong disease that affects the brain and spinal cord of people of all ages. ... This usually happens in people who are 50 and older. The progressive form of the disease is a

13 Sep 2021: By studying early signs of the disease and developing preventative treatments for people at risk a real difference could be made to the prevalence of the disease and the suffering caused

13 Sep 2021: Why is it important to undertake this work? In 2018, over 17 million new cases of cancer were diagnosed worldwide, while 9.6 million people died from the disease.

13 Sep 2021: Many people suffering from chronic pain are poorly treated by current medications, either due to a lack of efficacy (the drugs do not work), or due to intolerable side effects.

13 Sep 2021: This will allow people to learn about novel aspects of regenerative medicine and early cancer, and will provide the opportunity for a productive exchange of ideas between patients and scientists.

13 Sep 2021: Why is it important to undertake this work? Currently around 1 in 2 people will develop cancer in their lifetime. ... In the shorter-term this will involve making new discoveries on the types and behaviour of common gut bacteria found in people and how

13 Sep 2021: tumours). How are these learning outcomes important to the people on the course?

18 Jun 2021: Importantly, CH becomes increasingly common with age and is detected in more than 30% of people aged 70 years and older.

20 Aug 2021: This will help prevent people from getting kidney failure and make kidney transplants last longer, with important benefits; dialysis accounts for 2% of total NHS spending and transplantation restores patient independence

19 Aug 2021: Therefore, by testing different vaccines in mice with human immune systems we can identify better vaccines that are much more likely to work in people. ... Vaccine candidates that offer improved protection against malaria. A second generation Covid 19

19 Aug 2021: In January 2020, there were 6183 people in the UK currently waiting for an organ transplant, an increase in more than 1% on the previous year.

18 Jun 2021: For example, the Sugen-hypoxia protocol in rats, representing the combination of a drug (Sugen) and low oxygen levels similar to those experienced by people at a high altitude (hypoxia), leads ... The human disease develops slowly and only affects about

3 Mar 2021: the University of Cambridge. The aim of this induction document is to introduce AWERB members and lay people, scientists especially. ... to maintain their expertise. The role may be undertaken by a single person or by a number of people at a.

18 Jun 2021: We are trying to understand the earliest processes that go wrong because revealing how they work may point to new therapeutic targets that delay disease onset so that people can lead ... Clumps of tau also cause other dementias, such as frontotemporal

19 Aug 2021: Everyone working with animals will be supervised will be supervised and trained by experienced members of the lab, and when people with the required expertise are not available internally, we will