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30 Apr 2024: Why is it important to undertake this work? It is now predicted that 1 in 2 people will develop cancer in their lifetime and despite advances with new treatments they do ... We subscribe to the NC3Rs email updates and also receive regular updates from

30 Apr 2024: Downloaded: 9:21pm, 25 Apr 2024 Page 3 of 10. Dementias are the biggest health challenge of our generation; one in three people born today will develop the disease. ... With one million people in the UK predicted to have dementia by 2025 and the current

30 Apr 2024: benefit people living with mental health disorders through the development of new treatments. ... In the longer term, understanding the risk factors that predict whether individuals are more vulnerable to developing mental health disorders may allow

30 Apr 2024: Cancer, cardiovascular disease, diabetes and chronic respiratory diseases killed approximately 33.2 million people worldwide in 2019, a 28% increase compared to 2000. ... In the medium term this will allow us to choose the best designs or methods to take

29 Apr 2024: Why is it important to undertake this work? Despite decades of research, millions of people live with serious immune mediated disease such as colitis, arthritis, systemic lupus erythematosus (SLE) and atopic ... dermatitis. For example rheumatoid

29 Apr 2024: Each client is developing drugs which will hopefully contribute to helping people with various diseases with an unmet clinical need. ... For example, we have a large program of work studying haemophilia, a rare (1 in 30,000 people) but life-changing

30 Apr 2024: There are currently 6,079 people waiting for a transplant in the UK and many more who are not on the waiting list would benefit from having a diseased or damaged

30 Apr 2024: The most common form of arthritis, osteoarthritis (OA) is believed to affect an estimated 8 million people in the UK, and worldwide this figure rises to 343 million. ... OA is associated with age but younger people are also affected, often impacting on

30 Apr 2024: For example, Angelman syndrome, an imprinting disorder leading to severe intellectual disability affects 1 in 12,000-1 in 20,000 people worldwide, and Prader-Willi syndrome, another imprinting disorder linked ... to intellectual disability, compulsive

30 Apr 2024: With increased population lifespan, the incidence of people experiencing these devastating disorders will continue to rise. ... Our work has the potential to impact millions of people worldwide both at the social and economic levels.