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7 Dec 2022: The removal of specific references from the Non-Technical Summary. • Further clarification around the research into implants and the people they are aimed at in the Non-.

30 Apr 2024: Our plan is to publish research papers with new information on which human diseases involve programmed axon death and which specific people are most at risk. ... Individual people in families known to be at risk will also be able to determine their

18 Aug 2015: Opinion polls in the UK indicate that while many people willsupport some research using animals, they require that the research be forserious medical conditions and causes no unnecessary animal suffering. ... Human cell cultures aregrown under conditions

26 Sep 2012: This makes learning more flexible as people can complete units at a pace and in a way thatsuits their circumstances and helps providers and employers to create learning programmes that are

25 Sep 2015: throughout the University of Cambridge. The aim of this induction document is to introduce AWERB Members and Lay People, Scientists,. ... people undertaking Schedule 1 killing and those caring for animals) at the establishment is made known.

30 Apr 2024: We're working on a project that studies diseases that affect the entire nervous system, just like they would in people. ... This will help us get reliable data that can be used to develop and improve treatments for nerve diseases in people.

30 Apr 2024: Where possible in our design we blind people to genotype/treatment groups with different people doing infections or analysis. ... We will discuss any advances with the relevant people at our establishment and implement them accordingly.

30 Apr 2024: The World Health Organisation estimates that worldwide, 301 million people live with anxiety, 280 million people live with depression, and 326 million people experience post-traumatic stress disorder. ... benefit people living with mental health

13 Sep 2021: sugar control and lose weight, whilst decreasing or blocking the signals that make some people sick after surgery, thereby improving their post-surgical quality of live. ... the gut in a similar way used for the treatment of very overweight people.

18 Jun 2021: In both mice and people, digit tip regrowth depends on how much of the finger or toe is removed. ... makes us confident that any results we get will also be useful for people.

29 Apr 2024: As a result, while it is not possible at this stage to provide a meaningful estimate of the total number of people this technology would benefit it is clear that the

29 Apr 2024: It affects about 1 in 400 people in the UK. Crohn's disease affects about 1 in 700 people in the UK. ... In the shorter-term this will involve making new discoveries on the types and behaviour of common gut bacteria found in people and how these interact

13 Sep 2021: We will also be studying lung cancer. Nearly 45,000 new cases of lung cancer are diagnosed annually and nearly 35,000 people die from the disease in the UK every

13 Sep 2021: Furthermore, we do not understand how these bacteria spread in the environment and how they infect people. ... Doctors and patients will benefit from this research that will improve the treatment of sick people, especially children and will also reduce

18 Jun 2021: This includes developmental disorders such as progeria, an illness where people show signs of ageing and die early. ... It is estimated that 47 million people live with dementia around the world.

19 Aug 2021: Our research using animals has helped drive advances in cancer treatment that are benefiting people with cancer all over the world today. ... Studies of cancer in mice mimic the complex way tumours grow and spread in people with cancer.

30 Apr 2024: Why is it important to undertake this work? It is now predicted that 1 in 2 people will develop cancer in their lifetime and despite advances with new treatments they do ... We subscribe to the NC3Rs email updates and also receive regular updates from

30 Apr 2024: Downloaded: 9:21pm, 25 Apr 2024 Page 3 of 10. Dementias are the biggest health challenge of our generation; one in three people born today will develop the disease. ... With one million people in the UK predicted to have dementia by 2025 and the current

30 Apr 2024: benefit people living with mental health disorders through the development of new treatments. ... In the longer term, understanding the risk factors that predict whether individuals are more vulnerable to developing mental health disorders may allow

13 Sep 2021: With 3.3 billion people at risk of infection and 229 million people infected with malaria every year, resulting in over 409,000 annual deaths (WHO World Malaria report 2020). ... With billions of people at risk of infection, causing substantial disease

30 Apr 2024: Cancer, cardiovascular disease, diabetes and chronic respiratory diseases killed approximately 33.2 million people worldwide in 2019, a 28% increase compared to 2000. ... In the medium term this will allow us to choose the best designs or methods to take

29 Apr 2024: Why is it important to undertake this work? Despite decades of research, millions of people live with serious immune mediated disease such as colitis, arthritis, systemic lupus erythematosus (SLE) and atopic ... dermatitis. For example rheumatoid

29 Apr 2024: Each client is developing drugs which will hopefully contribute to helping people with various diseases with an unmet clinical need. ... For example, we have a large program of work studying haemophilia, a rare (1 in 30,000 people) but life-changing

30 Apr 2024: There are currently 6,079 people waiting for a transplant in the UK and many more who are not on the waiting list would benefit from having a diseased or damaged

30 Apr 2024: The most common form of arthritis, osteoarthritis (OA) is believed to affect an estimated 8 million people in the UK, and worldwide this figure rises to 343 million. ... OA is associated with age but younger people are also affected, often impacting on

19 Aug 2021: womb. We hope to identify novel targets for drug intervention to protect people from developing cardiovascular diseases later in life.

30 Apr 2024: For example, Angelman syndrome, an imprinting disorder leading to severe intellectual disability affects 1 in 12,000-1 in 20,000 people worldwide, and Prader-Willi syndrome, another imprinting disorder linked ... to intellectual disability, compulsive

30 Apr 2024: With increased population lifespan, the incidence of people experiencing these devastating disorders will continue to rise. ... Our work has the potential to impact millions of people worldwide both at the social and economic levels.

30 Apr 2024: Currently, there are 1.4 million people that are living with acquired brain injuries and 40,000 deaths only from stroke annually in the UK, and an estimated 69 million people

13 Sep 2021: Page 2 of 5. Our research aims to understand how and why mental health disorders occur, and to develop new treatments for people suffering from these disorders.

30 Apr 2024: Where possible in our design we blind people to genotype/treatment groups with different people doing infections or analysis. ... We will discuss any advances with the relevant people at our establishment and implement them accordingly.

30 Apr 2024: Whipworms infect 500 million people worldwide, particularly affecting children 5-15 years of age. ... Hookworms infect 450 million people around the globe, and can cause iron deficiency anaemia, especially in high-risk populations (children and women of

13 Sep 2021: Many people suffering from chronic pain are poorly treated by current medications, either due to a lack of efficacy (the drugs do not work), or due to intolerable side effects.

13 Sep 2021: Why is it important to undertake this work? Currently around 1 in 2 people will develop cancer in their lifetime. ... In the shorter-term this will involve making new discoveries on the types and behaviour of common gut bacteria found in people and how

13 Sep 2021: tumours). How are these learning outcomes important to the people on the course?

29 Apr 2024: Furthermore, to determine whether inhibition of the activities of these proteins will be effective in the treatment of people with cancer. ... Downloaded: 9:12pm, 25 Apr 2024 Page 6 of 11. Some mice can experience weight loss due to the effects of the

30 Apr 2024: In the UK, the number of people with dementia is estimated to exceed one million in 2025 (National Health Service - Dementia guide). ... memory in disorders such as dementia and dyslexia which significant number of people are suffering from.

20 Aug 2021: This will help prevent people from getting kidney failure and make kidney transplants last longer, with important benefits; dialysis accounts for 2% of total NHS spending and transplantation restores patient independence

19 Aug 2021: Therefore, by testing different vaccines in mice with human immune systems we can identify better vaccines that are much more likely to work in people. ... Vaccine candidates that offer improved protection against malaria. A second generation Covid 19

19 Aug 2021: In January 2020, there were 6183 people in the UK currently waiting for an organ transplant, an increase in more than 1% on the previous year.

30 Apr 2024: Finding treatments for all aspects of patient care therefore is crucial to improve outcomes for people affected. ... All clients that we work with are developing test agents which will hopefully contribute to helping people with various bleeding disorders

3 Mar 2021: the University of Cambridge. The aim of this induction document is to introduce AWERB members and lay people, scientists especially. ... to maintain their expertise. The role may be undertaken by a single person or by a number of people at a.

18 Jun 2021: For example, the Sugen-hypoxia protocol in rats, representing the combination of a drug (Sugen) and low oxygen levels similar to those experienced by people at a high altitude (hypoxia), leads ... The human disease develops slowly and only affects about

29 Apr 2024: treat people after they have contracted a disease. ... Future pandemics are inevitable as the global population expands - our vaccines aim to reduce the risk of such pandemics happening again, by protecting people through vaccination, against viruses of

30 Apr 2024: However, although many more people now survive, e.g., heart attacks and stroke, the debilitating consequences on quality of life and high risk of a secondary event leads to a huge

30 Apr 2024: They can cause significant burden to the patient, their families, and society as a whole; 14% of the social care budget in England is spent on people living with neurological conditions, ... Conditions involving neurodegeneration (when brain cells are

18 Jun 2021: We are trying to understand the earliest processes that go wrong because revealing how they work may point to new therapeutic targets that delay disease onset so that people can lead ... Clumps of tau also cause other dementias, such as frontotemporal

13 Sep 2021: people per million. ... This "Pulmonary Arterial Hypertension" (PAH) is usually diagnosed in people between the ages of 20 and 60, affecting more women than men.

19 Aug 2021: Everyone working with animals will be supervised will be supervised and trained by experienced members of the lab, and when people with the required expertise are not available internally, we will

19 Aug 2021: Why is it important to undertake this work? As life expectancy increases, there are a growing number of brain diseases affecting people.