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Research. The ordered assembly of specific proteins within neurons and glia is the hallmark of most neurodegenerative diseases. These proteins include TAR DNA-binding protein 43 (TDP-43), tau and α-synuclein. They form amyloid filament structures

Just another groups Multisite Sites site. Current projects. Structure and biophysics of major AMPA receptor complexes. AMPAR activation by glutamate involves a spectrum of conformational transitions referred to as ‘gating’. These ultimately open

/ Research. Research. In an effort to better understand human brain development, we have developed a new model system, called cerebral organoids. Cerebral organoids, or brain organoids, are 3D tissues generated from human pluripotent stem cells that

Yangqi Gu. Categories. Publications (5). August 10, 2022. Welcome to Yangqi who starts his first postdoc position with us after completing his PhD at Yale University. Footer. Chin Laboratory. MRC Laboratory of Molecular Biology. Centre for Chemical &

Just another LMB Group Multi Sites site. Rina Sakata. 17 October 2022. Rina is a Ph.D. student interested in stem cell models, genetic circuits, and understanding the earliest cell fate decisions of the developing human embryo. Before joining the

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