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12 Oct 2012: electronmicroscopy. We produced full-length, untagged Bt TubR andpurified it to homogeneity (Fig. ... Significantly thissuperstructure displays the positively charged DNA bindingsurface on the exterior of these helices (Fig.

11 Nov 2019: first try to solve a structure with heavy atom derivatives if molecular replacement. ... or are more flexible than the majority of the structure). Interactive display of the.

Phillips, Associate Director and structural biologist with AstraZeneca, resulted in the a href="https://www2.mrc-lmb.cam.ac.uk/dynamic-structure-human-dna-repair-enzyme-atm-revealed/"first three-dimensional ... the first ever polymerase for an uncharged

19 Apr 2018: First, prepare the condition with initial concentrations of reagents increased by 10% (min. ... Table 4: Programs available on the microsyringe-based nanoliter dispenser for additive screening.

25 Nov 2019: Fig. 2c and Extended Data Figs. 2 and 3). Based on biochemical analysis of stalling (Fig. ... When poly(A) first enters the A-site, it likely samples the helical state very rapidly.

21 Oct 2010: Results and DiscussionCrystal Structures of the TubZ Protofilament. We cloned and over-produced TubZ from B. ... 1B. TubZ possesses an addi-tional helical C-terminal tail, which is conformationally flexible.

5 Jul 2010: The rings are composed ofglobularsubunits and their power spectra display weak eightfold com-ponents (results not shown). ... of the membrane borders produced by high salt or EDTA isassociated with the detachment of particles from around the.

19 Apr 2002: The hinge domains of these bacterialphase. SMC proteins are sufficiently flexible that the two head. ... In the first case, the N- and5 Present address: Center for Cancer Research, Massachusetts Insti-.

4 Nov 2022: 183. Distinct Lipid Organization in the Two Leaflets. To display thefeatures responsible for the profile in Fig. ... Cholesterol monolayer films were produced at the air-water interface, using60 μL (4 mm diameter) water-filled Teflon wells.

30 Jan 2005: displays no detectable ATPase activity, a consequence of its. failure to bind nucleotide. ... MinE: first 35 amino acids (N-terminal domain). FtsA:last 20 amino acids.

3 Sep 2014: LeoABCshows splitting of the first gene into two as shown in Figure 1B and C. ... HHL JMJ JL. Wrote the paper: KAM HHL JL. First recognised LeoB/C.

4 Mar 2019: P. & Hirano, T. Condensin and cohesin display different arm conformations with characteristic hinge angles. ... N., Briscoe, G. & Erickson, H. P. The symmetrical structure of structural maintenance of chromosomes (SMC) and MukB proteins: long,

15 May 2007: nitrocellulose membrane was first stained with ponceau red for quantification of GST fusion proteins. ... This hypothesis was. first verified in vitro by testing the AP-2-binding properties.

20 Sep 2004: Burley, 2000) that binds to the Smc1 head. The first 32the sort of dimeric structures seen in our crystals. ... type or noncleavable Scc1 was expressed under control onset of the first anaphase (Figure 5C).

11 Aug 2015: The cryo-EMreconstruction of this native complex provided the first structure of SRP bound to the ribosome ina ‘scanning’ mode. ... Integration of SRP recruitment with the translational elongation cycle. (A) Stalled RNCs were produced.

11 Aug 2015: First, the region around the ribosome exit tunnel is highly crowded when bound to the translocon (Pfeffer et al., 2014). ... A) Short RNCs containing the pPL or N7a signal peptides were produced in reactions containing or lacking RMs.

15 Mar 2018: with tagO under inducible control display a teichoic acid-dependent decrease in width. ... cell contours (Figure 1—figure supplement 1B), suggesting the wall was becoming more flexible.

14 Jun 2006: Based on these cocrystal structures and a conserved. arylmorpholine pharmacophore model, structural models. ... These pioneering. studies were among the first to explore signaling by PI3-K.

19 Dec 2009: We fittedthe BDLP crystal structure and produced a molecularmodel for the entire filament. ... First, BDLP, which probably exists as dimer. in solution, is loaded with GTP (Figure 7A).

3 May 2017: First, FtsZ exhibits cooperative assembly, with a critical concentrationand a lag phase in assembly. ... situation of net growth at one end and netshrinkage at the other can be produced at certain monomer concentrations (additionreaction is first order