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30 Apr 2024: neurophysiological basis of visual cognition and memory will have far reaching social and economic implications. ... This test is important to allow animals to be directed into studies that they are most appropriate for.

19 Aug 2021: This project aims to improve our understanding of the cellular mechanisms that underlie IR injury and test the safety and efficacy of promising novel therapeutic agents. ... This project will generate academic outputs, new treatment products, and the

13 Sep 2021: The project will inform the development, and test the feasibility of novel therapeutic strategies to treat heart failure. ... Thus, animal experiments are essential to understand regulatory mechanisms and to design and test potential new therapies.

30 Apr 2024: of cognitive and emotional symptoms of neuropsychiatric disorders will have far reaching social and economic implications. ... can move freely once in the test apparatus and (iii) are tested for less than 40 minutes.

13 Sep 2021: We therefore wish to test if defects of the mouse EIF2AK4 gene can also be worsened by lung inflammation. ... be shown, and some account of the tests of significance to be made and the treatment differences that are to be estimated).

30 Apr 2024: This project aims to improve our understanding of the cellular mechanisms that underlie ischaemia-reperfusion injury (tissue damage caused when blood supply returns to tissue) and test the safety and effectiveness ... This project will generate academic

30 Apr 2024: The exact set of behavioural tests will be used is dependent on the mouse model being investigated. ... Our assessment includes both non-regulated and regulated tests, most having no noticeable adverse effects.

30 Apr 2024: We expect to uncover a pathway to promote myelin regeneration, and test its therapeutic potential. ... tests, or labelling (with dyes or fluorescent markers) the central nervous system under non recovery anaesthesia.

13 Sep 2021: This is why we need to use living animals to understand the complexity of the disease process and test the potential effect of new treatments. ... We will continue to test other non-animal strategies with the aim to replace the use of animals.

30 Apr 2024: This will help reduce the vast burden of pregnancy-induced origins of cardiovascular disease, thereby having a major clinical, economic, and societal impact on cardiovascular health. ... It may be possible in future to extend some of the work by using

29 Apr 2024: Each of our experiments is designed on the back of a robust statistical approach that relies on state-of-the-art statistical tests and models. ... covariance, and associated post-hoc tests, dimensional analyses, such as multiple and factorial regressions,

13 Sep 2021: Hence, medical conditions of the oesophagus represent an important social and economic burden, with a significant proportion of our public health budget spent in treatments that are inefficient and, in most ... 4. Test experiments, called pilot

30 Jun 2024: Most sections are followed by a "Test yourself" page of true/false questions.

14 Jun 2023: There are also:. Some self-assessment questions throughout the sections and an online test at the end of each section.

31 Jan 2023: profiling_of_test_agents_in_rodents_in_a_drug_discovery_platform_non-technical_summary_redacted.pdf (154.11 KB).

24 Jun 2024: The structure of a significance test using a two-sample t-test as an example. ... Non-parametric statistical tests and other simple tests to compare more complex data sets. •

9 Mar 2015: single test is a first step towards total replacement.

25 Sep 2015: number of such alternative methods. However, ‘alternative’ tests and models have yet to be. ... the animals, minimising the number of animals employed in each test, and avoiding.

14 May 2024: Researchers in the University’s Department of Surgery are using large animal models to understand why donated organs become damaged and unsuitable for transplantation, and to test promising new treatments.

7 Dec 2022: The committee acknowledged that while in the past this test has been overstated as a model of depression, under the right circumstances, this test still has validity. ... A ban on any test would remove this conversation entirely which the committee