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  2. AOC Minutes 22nd March 2024

    https://www.ubs.admin.cam.ac.uk/system/files/public/aoc_minutes_220324_redacted.pdf
    25 Apr 2024: 3. Establishment Licence Holder Report/Update. Forced swim test has now been removed from use in the UK. ... We received a PETA Freedom of Information request this week around forced swim tests, and we were able to tell them we don’t have any project
  3. Development of Live Bacterial Therapeutics to treat diseases with…

    https://www.ubs.admin.cam.ac.uk/system/files/public/development_of_live_bacterial_therapeutics_to_treat_diseases_with_intestinal_dysbiosis_non-technica_redacted.pdf
    29 Apr 2024: We aim to test the use of the mouse grimace scale for each protocol (https://nc3rs.org.uk/grimacescales).
  4. Environmental and placental contributions to pregnancy and life-long…

    https://www.ubs.admin.cam.ac.uk/system/files/public/environmental_and_placental_contributions_to_pregnancy_and_life-long_health_non-technical_summary_redacted.pdf
    29 Apr 2024: World Health Organisation, General Medical Council, Royal College of Veterinary Surgeons) and pharmaceutical organisations who may develop policies, diagnostic tests and therapies to combat sub/infertility, pregnancy complications and. ... It also
  5. Potent monoclonal antibodies for biologics discovery (non-technical…

    https://www.ubs.admin.cam.ac.uk/system/files/public/potent_monoclonal_antibodies_for_biologics_discovery_non-technical_summary_redacted.pdf
    30 Apr 2024: During the in vivo (performed in or on living animals) experiment, blood sample will be taken to test the generation of an antigen specific antibody response.
  6. Pharmacological evaluation of imaging agents and development of…

    https://www.ubs.admin.cam.ac.uk/system/files/public/pharmacological_evaluation_of_imaging_agents_and_development_of_imaging_applications_and_methods_no_redacted.pdf
    30 Apr 2024: We currently use several tests, depending on the kind of imaging agent, before proceeding to animal studies as follows.
  7. AWERB Standing Minutes 28th February 2024_Redacted

    https://www.ubs.admin.cam.ac.uk/system/files/public/awerb_standing_minutes_280224_redacted.pdf
    30 Apr 2024: The inclusion of further detail to support why specific tests are most appropriate for the science. ... Further detail required in the Animal Experience section. • The inclusion of a timeline to show when the tests will be performed and at what stage
  8. The development of novel therapies (including cell and gene based…

    https://www.ubs.admin.cam.ac.uk/system/files/public/the_development_of_novel_therapies_including_cell_and_gene_based_approaches_for_parkinsons_and_hu_redacted.pdf
    30 Apr 2024: as in vitro (performed in a test tube, culture dish or elsewhere outside of a living organism) slice cultures.
  9. Genes and environment at the interface of inflammation, immunity and…

    https://www.ubs.admin.cam.ac.uk/system/files/public/genes_and_environment_at_the_interface_of_inflammation_immunity_and_metabolism_non-technical_summa_redacted.pdf
    30 Apr 2024: Potential refinements include increased monitoring if test animals show earlier clinical signs or weight loss.
  10. AOC Minutes 19th January 2024

    https://www.ubs.admin.cam.ac.uk/system/files/public/aoc_minutes_190124_redacted.pdf
    25 Apr 2024: had their PAT test this week. will have theirs next week.
  11. The genetic and developmental basis of morphological and behavioural…

    https://www.ubs.admin.cam.ac.uk/system/files/public/the_genetic_and_developmental_basis_of_morphological_and_behavioural_variation_in_cichlid_fishes_no_redacted.pdf
    30 Apr 2024: Gene modifications are confirmed by collecting tissue biopsies (e.g. by removing a very small piece of fin or collecting skin swabs), which are then used for genetic tests.
  12. Cancer and its microenvironment! From mechanisms to translation…

    https://www.ubs.admin.cam.ac.uk/system/files/public/cancer_and_its_microenvironment_from_mechanisms_to_translation_non-technical_summary_redacted.pdf
    30 Apr 2024: A key component of this project is to improve the diagnosis and treatment of human cancers; therefore, it is crucial to test and validate novel tools in preclinical models that involve
  13. AWERB 3Rs Minutes 2nd August 2023 Redacted

    https://www.ubs.admin.cam.ac.uk/system/files/public/3rs_minutes_020823_redacted.pdf
    14 May 2024: Researchers in the University’s Department of Surgery are using large animal models to understand why donated organs become damaged and unsuitable for transplantation, and to test promising new treatments.
  14. Remodelling of stem cells and niche cells from development and…

    https://www.ubs.admin.cam.ac.uk/system/files/public/remodelling_of_stem_cells_and_niche_cells_from_development_and_regeneration_to_disease_non-technic_redacted.pdf
    30 Apr 2024: 4. Test experiments, called pilot experiments (which use a smaller number of animals; typically 3) will be used to calculate the amount of a substance that we can safely inject into
  15. 3Rs Minutes 7th August 2019 Redacted

    https://www.ubs.admin.cam.ac.uk/system/files/public/3rs_minutes_07.08.19_redacted.pdf
    14 May 2024: Increased monitoring and establishing disease progression through blood tests, if NSGs are needed to be kept for an extended period of time. •
  16. AOC Minutes 23rd February 2024

    https://www.ubs.admin.cam.ac.uk/system/files/public/aoc_minutes_230224_redacted.pdf
    25 Apr 2024: The PAT test is ongoing. 8. Training and Competencies It has been noticed that some people are still performing Schedule 1 that have not completed module 6.3.

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