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  2. How does the replisome respond to DNA damage? - MRC Laboratory of…

    https://www2.mrc-lmb.cam.ac.uk/how-does-the-replisome-respond-to-dna-damage/
    Thumbnail for How does the replisome respond to DNA damage? - MRC Laboratory of Molecular Biology 1 Jun 2018: Martin Taylor, from Joe’s group, recreated DNA replication in a test tube, using purified yeast replication proteins and yeast DNA templates.
  3. ProSHADE: ProSHADE Documentation

    https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/proshade/doxygen/index.html
    1 Nov 2018: Map fragmentation test OK. -----------------------------------------------. Features tests OK. -----------------------------------------------. Database functionality (this may take a while):. ===============================================.
  4. Discovering how translation and mRNA decay are linked - MRC…

    https://www2.mrc-lmb.cam.ac.uk/discovering-how-translation-and-mrna-decay-are-linked/
    Thumbnail for Discovering how translation and mRNA decay are linked - MRC Laboratory of Molecular Biology 21 Jun 2018: They then added them all to a test tube where they assembled into the complete active complex. ... Michael was then able to study the activity and regulation of Ccr4-Not in this test tube set-up.
  5. New insight into how membrane proteins are made - MRC Laboratory of…

    https://www2.mrc-lmb.cam.ac.uk/new-insight-into-how-membrane-proteins-are-made/
    Thumbnail for New insight into how membrane proteins are made - MRC Laboratory of Molecular Biology 9 Nov 2018: synthesised in a test tube.
  6. How replication of DNA is initiated at origins - MRC Laboratory of…

    https://www2.mrc-lmb.cam.ac.uk/how-replication-of-dna-is-initiated-at-origins/
    Thumbnail for How replication of DNA is initiated at origins - MRC Laboratory of Molecular Biology 16 Nov 2018: By assembling the yeast DNA replication machinery at a replication origin in a test tube, starting from individual purified components, Valentina Aria, from Joseph Yeeles’ group, was able to investigate the
  7. Manual_CO-311 JBScreen Solubility HTS

    https://www2.mrc-lmb.cam.ac.uk/screens2/pdf/SOLUB.pdf
    19 Mar 2018: In addition, both screens use equal ratio of protein and test condition, thereby making the effect of the buffer components in which the protein is stored more dominant. ... Finally, because, the screen tests for buffer, pH, salt and glycerol at the same
  8. How the earliest life on Earth may have replicated itself - MRC…

    https://www2.mrc-lmb.cam.ac.uk/how-the-earliest-life-on-earth-may-have-replicated-itself/
    Thumbnail for How the earliest life on Earth may have replicated itself - MRC Laboratory of Molecular Biology 16 May 2018: To test this theory of an ‘RNA world’, scientists have been trying to recreate a self-replicating RNA in the laboratory.
  9. LMB showcases the diversity of science at the Cambridge Science…

    https://www2.mrc-lmb.cam.ac.uk/lmb-showcases-the-diversity-of-science-at-the-cambridge-science-festival/
    Thumbnail for LMB showcases the diversity of science at the Cambridge Science Festival - MRC Laboratory of Molecular Biology 28 Mar 2018: Visitors could view ‘mini-brains’ in a dish and find out how these brain organoids are used to study brain development, and then test their matching skills in the ‘Where is
  10. HIV exploits a native cellular molecule to increase the stability of…

    https://www2.mrc-lmb.cam.ac.uk/hiv-exploits-a-native-cellular-molecule-to-increase-the-stability-of-its-capsid/
    Thumbnail for HIV exploits a native cellular molecule to increase the stability of its capsid - MRC Laboratory of Molecular Biology 31 May 2018: Finally, Donna teamed up with Adolfo Saiardi to devise a way to test whether IP.
  11. The Body's Daily Clock

    https://www2.mrc-lmb.cam.ac.uk/groups/mha/brain2.html
    20 Apr 2018: These remarkable cells can continue to keep their own 24 hour time in a test-tube for weeks even months on end.
  12. MD1-93 the Morpheus Additive Screen

    https://www2.mrc-lmb.cam.ac.uk/screens2/pdf/Addit-01.pdf
    5 Jul 2018: Test a large range of precipitants, stabilizers, buffers, nucleants, phasing compounds, cryoprotectants and surfactants all in one screen. •
  13. ProSHADE: ProSHADE_internal::ProSHADE_distances Class Reference

    https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/proshade/doxygen/d1/d6f/class_pro_s_h_a_d_e__internal_1_1_pro_s_h_a_d_e__distances.html
    1 Nov 2018: 2) Since structures failing the size test are removed completely from the comparison, the list of database structures becomes useless, as one does not know which were removed and which were ... in]. matchedStrNames. Pointer to a vector of strings which
  14. MD1-91, MD1-92 and MD1-92-FX Morpheus II 10 mL, HT-96 and FX-96…

    https://www2.mrc-lmb.cam.ac.uk/screens2/pdf/LMB20.pdf
    9 Jul 2018: Figure 1. Examples of crystals obtained during initial tests with the final formulation of Morpheus II.
  15. Journal of Visualized Experiments www.jove.com Copyright © 2018…

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/JOVE2018.pdf
    19 Apr 2018: Place a test plate on the motorized SBS carrier of the plate sealer. ... Repeat this test twice more to verify that the plate sealer is ready.3.
  16. MD1-46, MD1-47 and MD1-47-FX Morpheus 10 mL, HT-96 and FX-96…

    https://www2.mrc-lmb.cam.ac.uk/screens2/pdf/LMB17.pdf
    9 Jul 2018: Preliminary tests with Morpheus made within the Laboratory of Molecular Biology (LMB)1 at Cambridge, UK, have shown encouraging results with various targets.
  17. REFMAC5 Tutorial - Part 3

    https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/tutorials/refmac_tutorial/files/part_3.html
    23 Jun 2018: This will tell refmac to test whether the crystal is twinned, determine the number of twin domains, and refine the twin fractions.
  18. ProSHADE: ProSHADE_internal::ProSHADE_data Class Reference

    https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/proshade/doxygen/d1/dee/class_pro_s_h_a_d_e__internal_1_1_pro_s_h_a_d_e__data.html
    1 Nov 2018: For each box passing the tests, it then creates a new ProSHADE_data object in a vector of such objects it returns.
  19. 15211199233993 1..45

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/MreBHussain2018.pdf
    15 Mar 2018: thetic complex. To test this hypothesis, we examined MreB motions as we changed the shape of. ... increase with cell width (Ouzounov et al., 2016). To test if the angle of MreB movement changes.
  20. The ER membrane protein complex is a transmembrane domain insertase

    https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/Science_2017c.pdf
    27 Jan 2018: MEMBRANE TARGETING. The ER membrane protein complex isa transmembrane domain insertaseAlina Guna,1 Norbert Volkmar,2 John C. Christianson,2 Ramanujan S. Hegde1†. Insertion of proteins into membranes is an essential cellular process. The
  21. ProSHADE: src/proshade/ProSHADE_SO3transform.cpp Source File

    https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/proshade/doxygen/d7/db2/_pro_s_h_a_d_e___s_o3transform_8cpp_source.html
    1 Nov 2018: ProSHADE 0.6.5 (NOV 2018). Protein Shape Descriptors and Symmetry Detection. ProSHADE_SO3transform.cpp. Go to the documentation of this file.. 1. 21 //============================================ FFTW3 SOFT. 22 #ifdef __cplusplus. 23 extern "C" {.
  22. ProSHADE: src/proshade/ProSHADE_saveLoad.cpp Source File

    https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/proshade/doxygen/d0/df1/_pro_s_h_a_d_e__save_load_8cpp_source.html
    1 Nov 2018: ProSHADE 0.6.5 (NOV 2018). Protein Shape Descriptors and Symmetry Detection. ProSHADE_saveLoad.cpp. Go to the documentation of this file.. 1. 21 //============================================ RVAPI. 22 #include <rvapi_interface.h>. 23. 24 //=========

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