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Post-translational modifications
https://www2.mrc-lmb.cam.ac.uk/ccsb/research/post-translational-modifications/This allowed us to test how H3K56 acetylation may control diverse phenomena by altering higher order chromatin structure; remodelling or repositioning nucleosomes; allowing nucleosome core particle ‘breathing’ or opening on DNA; ... To test this, -
Integral component of the Wnt enhancesome identified - MRC Laboratory …
https://www2.mrc-lmb.cam.ac.uk/integral-component-wnt-enhancesome-identified/16 Mar 2017: allowed him to test the functional relevance of these elements during fly development and in human cells.
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LMB 365 - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/news-and-events/lmb-365/21 Jul 2023: During the last year, over 4,500 initial crystallisation screens were used at the LMB to test macromolecular samples of interest. ... This image for day 263 of #LMB365 shows a test spectrum created using precision sensors and software.
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RNA-seq course 2020 - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/research/scientific-training/rna-seq-course-2020/21 Jul 2023: The second video is a PRAGUI practical that will take you through the process of running PRAGUI step-by-step with some test data.
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New insight into how membrane proteins are made - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/new-insight-into-how-membrane-proteins-are-made/9 Nov 2018: synthesised in a test tube.
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Publications
https://www2.mrc-lmb.cam.ac.uk/groups/rh15/Publications.html14 Apr 2021: Faruqi, A.R. Ultramicroscopy 107, 73-80 (2007). Digitisation of electron microscope films: six useful tests applied to three film scanners. -
Discovering how translation and mRNA decay are linked - MRC…
https://www2.mrc-lmb.cam.ac.uk/discovering-how-translation-and-mrna-decay-are-linked/21 Jun 2018: They then added them all to a test tube where they assembled into the complete active complex. ... Michael was then able to study the activity and regulation of Ccr4-Not in this test tube set-up.
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Antiviral Bicycles are effective against SARS-CoV-2 - MRC Laboratory…
https://www2.mrc-lmb.cam.ac.uk/antiviral-bicycles-are-effective-against-sars-cov-2/16 Jun 2023: In order to turn the selected Bicycles into antivirals, Marina Vaysburd and Donna Mallery developed an assay to test for antiviral activity quickly and safely in the lab.
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New mechanism found that maintains intracellular water balance - MRC…
https://www2.mrc-lmb.cam.ac.uk/new-mechanism-found-that-maintains-intracellular-water-balance/18 Oct 2023: These concepts were tested using a broad range of experimental systems, including single proteins in a test tube, complex mixtures of biological molecules that exist within the cytoplasm, as well as
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Max Perutz Lecture to be given by John Diffley - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/max-perutz-lecture-to-be-given-by-john-diffley/20 Feb 2020: Recently they have developed a way of using these machines to copy DNA in a test tube, giving an unprecedented view of this fascinating and essential process.
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