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Mechanism of signal sequence handover from NAC to SRP on ribosomes…
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/wp-content/uploads/sites/8/2023/08/Science_2022.pdf27 Feb 2022: To test this, we compared the affinity ofNAC for RNCs displaying either an ER signalsequence (RNCSS) or a mutated signal sequencethat inhibits ER targeting (RNCSSmt) (fig. ... S17, B and C). Thus, thecontact between NAC UBA and SRP54 NG do-mains -
CURRICULUM VITAE
https://www2.mrc-lmb.cam.ac.uk/groups/bienz/wp-content/uploads/sites/23/BienzCV_March2024.pdf11 Apr 2024: signalling pathway in the Drosophila midgut. Development 122, 849-858. 47. Hart K & Bienz M (1996) A test for cell autonomy, based on di-cistronic messenger. -
4380 | G. J. Doherty et al. Molecular Biology ...
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Papers/Doherty2011/DohertyGRAF_MBC2011.pdf17 Jan 2012: Bars and error bars correspond to mean and SEM calculated from three independent experiments (n > 250; α = 0.05; two-tailed Fisher’s exact test, , p < 0.001). ... Bars and error bars correspond to mean and SEM (n = 12–15; α = 0.05; Student’s t -
Calcium-mediated Evidence from the Changes in Gap Junction Low ...
https://www2.mrc-lmb.cam.ac.uk/groups/nu/pdf/jcb83.pdf1 Nov 2012: Acid-washed glassware was used in experiments designed to test sensitivity o f gap j u n c t i o n structure to divalent cations. -
Substrate-specific regulation of the ribosome–translocon junction by…
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/17_Rutkowski_DT_PNAS_2001.pdf22 Jun 2001: To test this idea, we directly comparedthe translocation efficiencies of pPrl containing the pPrl, pbL, orpIgG signal sequences. ... translocation efficiency of bL-Prl and IgG-Prl. To test thishypothesis, we added either the first 5, 54, or 117 aa of the -
Cellular/Molecular Endophilin Drives the Fast Mode of Vesicle…
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Papers/Llobet%20J%20Neurosci2011.pdf23 Sep 2011: AnANOVA test confirmed that the amplitude of the fast phase wassignificantly reduced by endophilinSH3 (p 0.01). ... jneurosci.org as supplemental material), soit was important to test the specificity of its effect. -
MR_LMB
https://www2.mrc-lmb.cam.ac.uk/download/molecular-replacement/?wpdmdl=18799&refresh=66a660b22cf47172217976211 Jun 2013: approximate • conformational change. • Test multiple choices of model • easier in a pipeline: phenix.MRage, Balbes, MrBUMP • multiple templates,. -
pone.0107211 1..10
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/leoa2014.pdf3 Sep 2014: DLPs. We attempted to test this hypothesis directly but were. unable to obtain either individually, in combination, or expressed. -
Volume 22 May 15, 2011 1625 Cytosolic aggregates perturb ...
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/69_Chakrabarti_O_MBC_2011.pdf11 Nov 2011: The aggregated protein indicated at left was coexpressed with the test protein indicated along the top. ... At each time point, the % of aggregate-containing cells that showed excess intracellular accumulation of the test protein is indicated. -
doi:10.1128/mBio.00800-13. 4(6): .mBio. Midcell DNA Translocase FtsK…
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/mbio2013bisicchia.pdf23 Dec 2013: To test whether the translocase is responsiblefor promoting and maintaining the hexameric state of FtsK invivo, we determined the stoichiometry of an FtsK derivative lack-ing the C-terminal domain (FtsKC;
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