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New insight into how membrane proteins are made - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/new-insight-into-how-membrane-proteins-are-made/9 Nov 2018: synthesised in a test tube.
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Discovering how translation and mRNA decay are linked - MRC…
https://www2.mrc-lmb.cam.ac.uk/discovering-how-translation-and-mrna-decay-are-linked/21 Jun 2018: They then added them all to a test tube where they assembled into the complete active complex. ... Michael was then able to study the activity and regulation of Ccr4-Not in this test tube set-up.
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RNA-seq course 2020 - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/research/scientific-training/rna-seq-course-2020/21 Jul 2023: The second video is a PRAGUI practical that will take you through the process of running PRAGUI step-by-step with some test data.
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https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/18646
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/18646{"id":18646,"date":"2020-07-17T17:09:31","date_gmt":"2020-07-17T16:09:31","guid":{"rendered":"https://www2.mrc-lmb.cam.ac.uk/?p=18646"},"modified":"2021-11-18T10:32:25","modified_gmt":"2021-11-18T10:32:25","slug":"putting-science-skills-to-new-use-du -
Scheres lab
https://www2.mrc-lmb.cam.ac.uk/groups/scheres/publications.html3 May 2024: Our publications. 2024. A. Burt, B. Toader, R. Warshmanage, A. von Kugelgen, E. Pyle, J. Zivanov, D. Kimanius, T.A.M. Bharat & S.H.W. Scheres (2024) "An image processing pipeline for electron cryo-tomography in RELION-5". bioRxiv 2024.04.26.591129. -
Coot
https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/21 Mar 2024: Yes - welcome. Crystallographic Object-Oriented Toolkit. Coot is for macromolecular model building, model completion and validation, particularly suitable for protein modelling using X-ray data. Coot displays maps and models and allows model -
Work Experience - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/students/work-experience/10 Jun 2024: I particularly enjoyed learning about and examining Drosophila melanogaster, as well as learning about how they could be used to aid research and test out theories in the lab.
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https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/20739
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/20739 -
How does the replisome respond to DNA damage? - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/how-does-the-replisome-respond-to-dna-damage/1 Jun 2018: Martin Taylor, from Joe’s group, recreated DNA replication in a test tube, using purified yeast replication proteins and yeast DNA templates.
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Index of /personal/pemsley/coot/files
https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/files/coot-trial-adding-up-test.tar.gz. ... ligand-fitting-test-2-no-ligand.mtz. -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/19083
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/19083{"id":19083,"date":"2020-09-03T11:49:53","date_gmt":"2020-09-03T10:49:53","guid":{"rendered":"https://www2.mrc-lmb.cam.ac.uk/?page_id=19083"},"modified":"2023-07-21T12:49:55","modified_gmt":"2023-07-21T11:49:55","slug":"rna-seq-course-2020","status": -
Scheres lab
https://www2.mrc-lmb.cam.ac.uk/groups/scheres/structures.html7 Mar 2022: Our structures. Our methods aim to open up new experimental possibilities in Structural Biology studies. By ourselves or through collaborations, we have used our methods to determine new structures. Some of these structures are described here. For -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/14619
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/14619{"id":14619,"date":"2019-07-03T10:47:14","date_gmt":"2019-07-03T09:47:56","guid":{"rendered":"https://www2.mrc-lmb.cam.ac.uk/?page_id=14619"},"modified":"2023-07-21T12:49:43","modified_gmt":"2023-07-21T11:49:43","slug":"mesolens-microscopy-2009","sta -
Putting science skills to new use during the pandemic - MRC…
https://www2.mrc-lmb.cam.ac.uk/putting-science-skills-to-new-use-during-the-pandemic/17 Jul 2020: The people I have been working with at the test centre were truly amazing. ... It is only with your generous support that we have been able to test COVID-19 samples at such enormous scale.
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https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/21995
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https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/20344
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/20344{"id":20344,"date":"2021-04-20T11:59:40","date_gmt":"2021-04-20T10:59:40","guid":{"rendered":"https://www2.mrc-lmb.cam.ac.uk/?p=20344"},"modified":"2021-05-05T09:58:45","modified_gmt":"2021-05-05T08:58:45","slug":"2021-max-perutz-lecture-to-be-given- -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/19159
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/19159{"id":19159,"date":"2020-10-13T12:19:35","date_gmt":"2020-10-13T10:19:22","guid":{"rendered":"https://www2.mrc-lmb.cam.ac.uk/?page_id=19159"},"modified":"2023-07-21T12:51:44","modified_gmt":"2023-07-21T11:51:44","slug":"liz-miller-signed-sealed-deliv -
Isothermal titration calorimetry to measure protein/peptide/lipid…
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/techniqs/ITC.html26 Sep 2011: Isothermal Titration Calorimetry is used to make accurate measurements of affinities and stoichiometries of interactions. It is based on fine measurements of heat changes when ligands interact -
ProSHADE: ProSHADE Documentation
https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/proshade/doxygen/index.html1 Nov 2018: Map fragmentation test OK. -----------------------------------------------. Features tests OK. -----------------------------------------------. Database functionality (this may take a while):. ===============================================. -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/19090
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/19090{"id":19090,"date":"2020-09-03T15:00:35","date_gmt":"2020-09-03T13:00:00","guid":{"rendered":"https://www2.mrc-lmb.cam.ac.uk/?page_id=19090"},"modified":"2023-07-21T12:51:37","modified_gmt":"2023-07-21T11:51:37","slug":"anne-bertolotti-finding-clues- -
https://www2.mrc-lmb.cam.ac.uk/ccsb/wp-json/
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https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/18964
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/18964{"id":18964,"date":"2020-08-18T14:05:27","date_gmt":"2020-08-18T13:05:27","guid":{"rendered":"https://www2.mrc-lmb.cam.ac.uk/?p=18964"},"modified":"2022-03-21T15:56:30","modified_gmt":"2022-03-21T15:56:30","slug":"studying-the-spike-protein-of-sars-c -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/19788
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/19788{"id":19788,"date":"2021-01-25T10:06:14","date_gmt":"2021-01-28T11:29:36","guid":{"rendered":"https://www2.mrc-lmb.cam.ac.uk/?page_id=19788"},"modified":"2021-03-31T11:01:03","modified_gmt":"2021-03-31T10:01:03","slug":"behind-the-scenes-maria-daly-a -
https://www2.mrc-lmb.cam.ac.uk/groups/cartera/wp-json/
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https://www2.mrc-lmb.cam.ac.uk/groups/munro/wp-json/
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LMB Nobel Prizes - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/achievements/lmb-nobel-prizes/21 Jul 2023: They are awarded annually for achievements in the fields of physics, chemistry, physiology or medicine, literature, peace and economic sciences.
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https://www2.mrc-lmb.cam.ac.uk/groups/hegde/wp-json/
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https://www2.mrc-lmb.cam.ac.uk/groups/greger/wp-json/
https://www2.mrc-lmb.cam.ac.uk/groups/greger/wp-json/ -
timeline | The Bacterial Cytoskeleton and other Molecular Machines
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/page12/index.html29 Apr 2024: In order to test whether the mode of DNA binding revealed by cryo-EM also occurs in cells, we genetically engineered E. -
https://www2.mrc-lmb.cam.ac.uk/groups/sbullock/wp-json/
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https://www2.mrc-lmb.cam.ac.uk/groups/nguyen/wp-json/
https://www2.mrc-lmb.cam.ac.uk/groups/nguyen/wp-json/ -
https://www2.mrc-lmb.cam.ac.uk/groups/bharat/wp-json/
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https://www2.mrc-lmb.cam.ac.uk/groups/allegretti/wp-json/
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https://www2.mrc-lmb.cam.ac.uk/groups/lancaster/wp-json/
https://www2.mrc-lmb.cam.ac.uk/groups/lancaster/wp-json/ -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/7087
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/7087forum-davos/","title":{"rendered":"Venki Ramakrishnan at World Economic Forum in Davos"},"content":{"rendered":". The end of the antibiotic age? ... The LMB’s Venki Ramakrishnan took part in a panel discussion on the problem of antibiotic resistance at -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/1014
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/1014Where possible, scientists are encouraged to exploit and disseminate their discoveries u2013 helping to improve quality of life and the economic competitiveness of the UK and pioneering new research methods. -
LMB COVID-19 response - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/research/lmb-covid-19-response/22 Nov 2023: How can we test for, treat and prevent SARS-CoV-2 infection? Collaborators across the LMB have developed new models, assays, and screening platforms with the goal of investigating new methods ... and drugs that could be used to test for or treat COVID-19.
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https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/18288
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/1828835","modified_gmt":"2020-06-25T08:36:35","slug":"researchers-in-vienna-including-lmb-phd-student-max-kellner-develop-a-new-quick-and-easy-covid-19-test","status":"publish","type":"post"," ... including LMB PhD student Max Kellner, develop a new -
Annette Faux (1966-2023) - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/annette-faux-1966-2023/19 Oct 2023: morning to test their knowledge in PopMaster (as an avid music collector all her life Annette was an impressive player, though Teresa’s extensive knowledge of the 1950s and 1960s left
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Buzz Baum - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/group-leaders/a-to-g/buzz-baum/22 Mar 2024: In doing so, we will put the “inside-out model” for the origin of the eukaryote cell to the test.
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Public Engagement - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/news-events/public-engagement/feed/19 Jul 2024: first time in a three-dimensional cryo-EM image./p pThis collaboration started in early 2019 when Radu and Abhay Kotecha, a researcher at Thermo Fisher Scientific, wanted to test new ... of vaccines and diagnostic tests./p pThe post a -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/239
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/239{"id":239,"date":"2012-06-25T11:48:48","date_gmt":"2012-06-25T11:48:48","guid":{"rendered":"http://www2.mrc-lmb.cam.ac.uk/wordpress/?page_id=239"},"modified":"2023-07-21T12:51:53","modified_gmt":"2023-07-21T11:51:53","slug":"lmb-nobel-prizes","status -
Banana - Experiments on Microscopes 4 Schools
https://www2.mrc-lmb.cam.ac.uk/microscopes4schools/banana.phpLugol solution is a solution of iodine and potassium iodide in water and it is used as an indicator test for the presence of starches, with which it reacts by turning -
Fast Facts - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/about-lmb/fast-facts/21 Jul 2023: LMB discoveries help fuel the UK’s life sciences industry – the third largest contributor to economic growth.
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John Kilmartin - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/group-leaders/emeritus/john-kilmartin/21 Jul 2023: 2. transport by haemoglobin and the Bohr effect. He prepared specifically modified haemoglobins to test whether particular amino acids, some predicted from the X-ray crystallographic structure Perutz had just solved,
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https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/32564
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/32564{"id":32564,"date":"2023-04-17T15:08:47","date_gmt":"2023-04-17T14:08:47","guid":{"rendered":"https://www2.mrc-lmb.cam.ac.uk/?p=32564"},"modified":"2023-04-17T15:08:48","modified_gmt":"2023-04-17T14:08:48","slug":"understanding-the-protein-modificati -
Marta Zlatic - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/group-leaders/t-to-z/marta-zlatic/23 Feb 2024: with comprehensive structural and functional connectivity maps, and iv) use powerful genetic tools to selectively manipulate individual neurons to test models’ predictions and elucidate the functional roles of specific circuit motifs.
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Scientific Glossary - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/news-and-events/scientific-glossary/21 Jul 2023: Alongside applications in research, this capacity is also used for medical tests, such as to test for the presence of viral RNA, including in COVID-19 tests.
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Atomic advance for cryo-EM - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/atomic-advance-for-cryo-em/21 Oct 2020: This collaboration started in early 2019 when Radu and Abhay Kotecha, a researcher at Thermo Fisher Scientific, wanted to test new cryo-EM hardware on a small membrane protein sample.
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https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/215
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/2152. transport by haemoglobin and the Bohr effect. He prepared specifically modified haemoglobins to test whether particular amino acids, some predicted from the X-ray crystallographic structure Perutz had just solved, ... He prepared specifically modified
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