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  1. Results that match 1 of 2 words

  2. 14821680963433 1..18

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/e21600-download.pdf
    19 Dec 2016: crenactin filaments. To test this, we performed. the same experiment using a peptide spanning.
  3. Chapter 20 In Vitro Dissection of Protein Translocationinto the ...

    https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/62_Sharma_AS_MMB_2010.pdf
    30 Apr 2010: 2. Layer this onto 100 µL of the sucrose cushion in an ultra-centrifuge tube (either a tube for the TLA120.1 rotor or amicro-test tube for the TL100.3 ... 1. Using glass measuring tools (e.g., glass pipettes), transfer20 mg PC and 5 mg PE to a glass
  4. The Jour nal o f Cel l Bio logy ...

    https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/24_Fons_RD_JCB_2003.pdf
    6 Feb 2003: To test whether the tetrameric TRAP complex alone wasthe component that stimulates. ... To test this, we analyzed theTRAP dependence of two point mutations in the PrP signalsequence (termed N7 and N9 [Fig.
  5. 088542u047

    https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Owen_McMahon1999.pdf
    17 Mar 2003: In order to test the validity of this hypoth-by six residues to complete the b strand, resulted in a.
  6. Protein-driven membrane stresses in fusion and fission

    https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Papers/KozlovCurvature2010.pdf
    21 Feb 2011: Science 321, 1354–1357. 62 Sever, S. et al. (2000) Garrotes, springs, ratchets, and whips: puttingdynamin models to the test.
  7. The Jour nal o f Cel l Bio logy ...

    https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/26_Snapp_EL_JCB_2003.pdf
    16 Oct 2003: To test this, we fused GFP or YFP to thecytoplasmic domains of three resident ER membrane proteinswith minimal cytoplasmic domains: two rough ER com-ponents of the translocon, Sec61. ... chimera. To test if OSER-inducing, GFP-tagged ER proteinswere
  8. refmac keywords

    https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/refmac/refmac_keywords.pdf
    12 Jan 2012: V3000 has not beentested yet. If somebody wants to test please let me know.
  9. Qrb1300006 1..40

    https://www2.mrc-lmb.cam.ac.uk/groups/nu/pdf/qrb13.pdf
    30 Jul 2013: twist around the tube axis). Preliminary tests using a segment size similar to that in Fig.
  10. Tutorial 2: Descriptive Statisticsand Exploratory Data Analysis…

    https://www2.mrc-lmb.cam.ac.uk/download/tutorial-2-descriptive-statistics-2/?wpdmdl=18820&refresh=6693eb1c5023a1720970012
    20 Mar 2014: Petal.Width and systematically higher Sepal.Width thanthe other two species, although to draw such conclusions we would have to test suchhypotheses properly).
  11. Asymmetric distribution of pause transfer sequences in apolipoprotein …

    https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/6_Kivlen_MH_JLR_1997.pdf
    30 May 2008: Experiments must now be designed to test this hypothesis. Translocational pausing has been viewed as a mecha- nism by which particular regions of the nascent chain can be isolated from the
  12. SVUS002-16.tex

    https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/31_Rane_Chapter_2005.pdf
    21 Sep 2006: Meanwhile, the most definitive test for prions, a bioassay, was be-ing performed in parallel on comparable samples3639. ... These toolscan then be used in vivo to test specific hypotheses regarding the patho-genesis of prion diseases.
  13. Membrane transport between compartments in eukary-otic cells requires …

    https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Dynaminreview2004.pdf
    2 Feb 2004: 4) have been used asassembly tests for other members of the dynamin family(see Oligomerization web site in Online links). ... This clathrin-centricmodel for endocytosis does not, however, take intoaccount the role of dynamins in
  14. THE JOURNAL OF BIOLOGICAL CHEMISTRY 0 1990 by The ...

    https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/1_Pewitt_EB_JBC_1990a.pdf
    29 Dec 2004: In order to test whether stimulated [3H]bumetanide binding would be re- tained in membranes after activation of transport by agents other than catecholamines, we examined specific binding in membranes from
  15. Tumour prevention by a single antibody domaintargeting the…

    https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/17568777.pdf
    22 Jul 2007: In addition,. using mouse models as a preclinical test, as we have done in.
  16. doi:10.1016/j.jmb.2004.12.031

    https://www2.mrc-lmb.cam.ac.uk/groups/nu/pdf/jmb05.pdf
    24 Jan 2005: The model-derivedphases provided a more sensitive test of the signalretained in the images at high resolution than theprevious reference, which had been derived solelyfrom the images.
  17. Cell, Vol. 91, 575–582, November 28, 1997, Copyright 1997 ...

    https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/9_Hegde_RS_Cell_1997.pdf
    20 Nov 1997: Although the signifi-. cance of these findings remains to be determined, the Indeed, the contradicting conclusions resulting frommany of the studies which each used different test sub-rearrangements of the
  18. The Structure of a Tunicate C-type Lectin from Polyandrocarpa…

    https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/10398588.pdf
    7 Jul 1999: The residuals betweenthe tted absorbance and the experimental values wereplotted, to test for the validity of the model used.
  19. doi:10.1016/j.devcel.2004.09.003

    https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/15469844.pdf
    1 Nov 2004: An analogous salt link is formed betweenattractive proposal. To test this, we made an N-terminalArg83 of Vps25 and Asp548 of Vps36.
  20. se060101051p

    https://www2.mrc-lmb.cam.ac.uk/groups/hmm/AP180/Ap180_st.pdf
    3 Dec 2004: test-ed by sedimentation assays using liposomesor lipid tubules (19, 27, 28). ... Each assay contained0.05 mg/ml protein. (B) Liposomes containing 10%cholesterol, 40% phosphatidylethanolamine, 40%phosphatidylcholine, and 10% of a test lipid wereprepared
  21. Tutorial 2: Descriptive Statisticsand Exploratory Data Analysis…

    https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/courses/lmb_statistics_course_2014/tutorials/descriptive_statistics_and_exploratory_data_analysis_answers.pdf
    20 Mar 2014: Petal.Width and systematically higher Sepal.Width thanthe other two species, although to draw such conclusions we would have to test suchhypotheses properly).
  22. BAR Domains as Sensors ofMembrane Curvature: TheAmphiphysin BAR…

    https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/PeterBARdomains.pdf
    30 Jan 2004: T-tubule net-work (7 ). To test if this tubulating ability is dueto the Drosophila amphiphysin BAR domain,we mutated pairs of basic residues to gluta-mates, Lys161 Lys163 on the ... S3B). As a functional test of the amphiphysin BARdomain, we tested the
  23. Combinatorial Control of Prion Protein Biogenesis by the…

    https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/18_Kim_SJ_JBC_2001.pdf
    26 Jun 2001: The present work has generated a wide arrayof tools to test this and other hypotheses in future studies.
  24. Wild card macros

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/sciencegayathri2012/Gayathri.SM.pdf
    23 Oct 2012: parenthesis. † Rmerge = ΣΣ | Ihl - 〈Ih〉 | / ΣΣ 〈Ih〉 h l h l ‡ 5 % of the reflections were included in the test set.
  25. The GTPase-Activating Protein GRAF1 Regulates the CLIC/GEEC Endocytic …

    https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Papers/Lundmark_McMahon_GRAF2008.pdf
    28 Nov 2008: The error bars show 95% confidence intervals (calculated by t tests) for each condition.
  26. MeganPalm

    https://www2.mrc-lmb.cam.ac.uk/groups/wschafer/MeganPalm.pdf
    3 Dec 2005: previously used for the egg detection test and 20 new normal wild type videos. ... type. To test whether unc-29(x29) was clustering in the correct region, data obtained.
  27. Tutorial 6: Linear RegressionRob Nicholls –…

    https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/courses/lmb_statistics_course_2014/tutorials/linear_regression.pdf
    31 Mar 2014: This essentially tests whether the. Tutorial 6: Linear Regression 4. model has any predictive power. ... b) Create a model to test this hypothesis, assuming a linear relationshipbetween Height and Girth.
  28. The structural basis of novel endosome anchoringactivity of KIF16B ...

    https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/17641687.pdf
    23 Jul 2007: To further test this notion, we performed two independent. measurements. First, we monitored by SPR analysis the.
  29. REPORT◥ PROTEOSTASIS UBE2O is a quality control factor fororphans ...

    https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/Science_2017b.pdf
    4 Aug 2017: Fig. 2. Reconstitution ofUBE2O-mediated clientubiquitination with purifiedfactors. (A) Experimentalstrategy to test UBE2O inter-action and ubiquitination in adefined system.
  30. Modeling membrane shaping by proteins: Focus on EHD2 and N-BAR domains

    https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Papers/KozlovEHDs.pdf
    7 Apr 2010: FEBS Letters 584 (2010) 1830–1839. j o u r n a l h o m e p a g e : w w w. F E B S L e t t e r s. o r g. Review. Modeling membrane shaping by proteins: Focus on EHD2 and N-BAR domains. Felix Campelo a,b, Gur Fabrikant a, Harvey T. McMahon c,
  31. Phosphoinositide-Specific Phospholipase Cδ1 Activity toward Micellar…

    https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/9287165.pdf
    20 Apr 2002: of theδ1 enzyme show similar structural features, it was of interestto test the mammalianδ1 enzyme for activation by organicsolvent.
  32. Statistical Theory; Why is the Gaussian Distribution so popular? ...

    https://www2.mrc-lmb.cam.ac.uk/download/statistical-theory-why-is-the-gaussian-distribution-so-popular-rob-nicholls/?wpdmdl=18809&refresh=6693eb1cb790c1720970012
    17 Mar 2014: Compare means to test for differences. • Consider variance (and shape) of the distributions – help choose appropriate prior/protocol. •
  33. BAR Domains as Sensors ofMembrane Curvature: TheAmphiphysin BAR…

    https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/PeterBARdomains.pdf?ijkey=TikQO8xVkpUak&keytype=ref&siteid=sci
    30 Jan 2004: T-tubule net-work (7 ). To test if this tubulating ability is dueto the Drosophila amphiphysin BAR domain,we mutated pairs of basic residues to gluta-mates, Lys161 Lys163 on the ... S3B). As a functional test of the amphiphysin BARdomain, we tested the
  34. Molecular Biology of the CellVol. 19, 5093–5103, December 2008 ...

    https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Papers/LynchMBC5093.pdf
    24 Jan 2009: significantly (p 0.002)from wild-type and Syt-1RK by a general linear model analysis of variance using the Tukey post hoc test of values.
  35. CAN-11-2008 3642..3651

    https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/79_Basseville_A_CanRes_2012.pdf
    24 Sep 2015: Statistical analysisThe Student t test was carried out for each experiment.
  36. Protection from cytosolic prion protein toxicityby modulation of…

    https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/30_Rane_N_EMBO_2004.pdf
    8 Nov 2004: To test this possibility, we analyzed the behavior of PrP. constructs containing mutations in the transmembrane do-.
  37. Relocalization of STIM1 for Activation of Store-operated Ca2!Entry Is …

    https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/47_Ong_HL_JBC_2007.pdf
    24 Sep 2015: previous report (15). We wanted to test whether a model withtwo ER compartments that are functionally distinct but slowlyequilibrate with each through diffusion of Ca2!
  38. A positively charged channel within the Smc1/Smc3 hinge required for…

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/embosmcjingekurze2010.pdf
    1 Dec 2010: generate sister chromatid cohesion. To test the effect of charge neutralization on cohesin complex.
  39. FtsA forms actin-like protofilaments

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/EMBO2012FtsAPiotr/emboj201276a.pdf
    27 Mar 2012: be the most reliable test for FtsA polymerization, as it shows.
  40. Supplement_Final

    https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/81_Shao_S_Mol_Cell_2013.pdf
    16 May 2013: To test this idea, we produced RNCs ina ubiquitination-deficient lysate (Hessa et al., 2011) depleted ofthe requisite E2s and ubiquitin (Figure 4C). ... This suggests that their combinationprovides the specificity for Listerin recruitment. To test
  41. Structural Mapping of the Catalytic Mechanism for a…

    https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/9048554.pdf
    20 Apr 2002: Data statistics are listed in Table1. Test data for the calculation of freeR factors of all thesedata sets were chosen to be consistent with the selection oftest data for the native
  42. Cryo‐EM structure of the MinCD copolymeric filament from Pseudomonas…

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/Szewczak-Harris_et_al-2019-FEBS_Letters.pdf
    22 Jul 2019: by MinD’s MTS. To test whether P. aeruginosa MinC and MinD pro-.
  43. Membrane Protein Insertion at the Endoplasmic Reticulum

    https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/75_Shao_S_Ann_Rev_2011.pdf
    9 Nov 2011: The apparentfree-energy contribution of each amino acidin any test sequence was found to be additive,with the sum determining the final insertionprobability. ... earlier transmembrane domains ( gray), and a later test sequence(red ) is measured for
  44. Science Journals — AAAS

    https://www2.mrc-lmb.cam.ac.uk/groups/hegde/wp-content/uploads/sites/8/2023/08/Science_2021.pdf
    26 Aug 2021: p values for a two-tailedStudent’s t test comparison to Q1are indicated.
  45. 554 Research Paper Inhibition of receptor-mediated endocytosis by the …

    https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/wigge_McMahon1997.pdf?cmd=Retrieve&db=PubMed&list_uids=9348539&dopt=Abstract
    21 Mar 2003: To test whether the cellulartarget of amphiphysin is dynamin, COS-7 cells were cotransfected with bothdynamin and the amphiphysin SH3 domain; here, transferrin uptake wasefficiently rescued. ... To test the hypothesis that the SH3 domain ofamphiphysin is
  46. Twinning and other pathologies Andrey Lebedev CCP4 OD-­‐structures…

    https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/%22https:/www2.mrc-lmb.cam.ac.uk/download/twinningaandaotherapathologiesa-andreyalebedeva-a/?wpdmdl=18788&
    11 Jun 2013: Twinning tests summary. Space group validaAon. 04/06/2013 58 Crystallography Course LMB. ... Twinning tests summary. Space group validaAon. 04/06/2013 61 Crystallography Course LMB.
  47. The Hydrophobic Insertion Mechanism of Membrane Curvature Generation…

    https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Papers/CampeloBioPJ2008.pdf
    13 Dec 2008: 5). To test the sensitivity of the model. predictions to this assumption, we repeated the calculations.
  48. Expression, purifica0on, characteriza0on, and crystalliza0on So how…

    https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/%22https:/www2.mrc-lmb.cam.ac.uk/download/03-protein-expression-crystallization-and-mutagenesis-meindert-lamers/?wpdmdl=18793&
    2 May 2013: Beware of the layer of cold air over the liquid nitrogen (2) Test crystal at room temp: Mitegen crystal sleeve: MicroRT Test different cryos & precipitant concentra-ons Remove any mother liqour
  49. Regulation of lipid binding underlies the activation mechanism of…

    https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/22120714.pdf
    21 Nov 2012: Oncogene. Correlation of lipid kinase activity with lipid bindingTo test whether lipid binding forms the basis of p110activation, we compared lipid kinase with lipid-bindingactivities for three sets of p110a/p85a
  50. Reconstitution of a prokaryotic minus end-trackingsystem using TubRC…

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/PNAS-2015-Fink-E1845-50.pdf
    27 Apr 2015: To test for seeding, we followed filament formation onimmobilized TubRC complexes (Fig.
  51. pone.0052401 1..15

    https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Papers/Podosome2012/journal.pone.0052401.pdf
    10 Jan 2013: Test set size (%) 5.4. Rwork (%) 19.6(22.9). Rfree (%) 25.2(23.8). ... Significance was calculated using the Student’s t test( = p,0.05). D: Confocal micrographs of RAM cells over-expressing Bin2-EGFP (Bin2, green, left) or control (EGFP, green, right).

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