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Venki Ramakrishnan at World Economic Forum in Davos - MRC Laboratory…
https://www2.mrc-lmb.cam.ac.uk/venki-ramakrishnan-world-economic-forum-davos/23 Jan 2015: Venki Ramakrishnan at World Economic Forum in Davos. Published on. 23 January, 2015. ... The end of the antibiotic age? The LMB’s Venki Ramakrishnan took part in a panel discussion on the problem of antibiotic resistance at the World Economic Forum in -
Unfinished proteins: how to find a needle in the haystack - MRC…
https://www2.mrc-lmb.cam.ac.uk/unfinished-proteins-find-needle-haystack/9 Jan 2015: In earlier work, the Hegde group had discovered how to carry out the tagging reaction in a test tube and found that Listerin is the enzyme that adds ubiquitins (the degradation ... Exploiting this test tube system, Susan worked out the sequence of steps -
Effects of caffeine on the human circadian clock - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/effects-of-caffeine-on-the-human-circadian-clock/17 Sep 2015: Trials are needed to test the latter, and it will be important to monitor for caffeine-induced sleep disruption under such conditions, which could worsen jet lag. -
Golden grids for electron microscopy licensed by Quantifoil - MRC…
https://www2.mrc-lmb.cam.ac.uk/golden-grids-for-electron-microscopy-licensed-by-quantifoil/30 Mar 2015: Since their recent development at the LMB, external scientists have been eager to test these gold grids: this exciting technology will now be available to all researchers, allowing them to use -
Sensory Neurons Arouse C. elegans Locomotion via Both Glutamate and…
https://www2.mrc-lmb.cam.ac.uk/groups/wschafer/2015-4.pdf30 Jun 2015: Scale bar indicates 10 μm. p values are indicated for each comparison (Kolmogorov-Smirnov test). ... Statistical significance was determined using one-way ANOVA with Tukey test for multiple comparisons. -
Paul EmsleyMRC Laboratory of Molecular Biology, Cambridge, UKJune…
https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/files/Ligands-July-2015-v2.pdf16 Jul 2015: Can today's Acedrg fill the gaps? Acedrg Tests. Take the wwPDB Chemical Component Dictionary. ... Test vs Mogul worst z-score. Distortion: using Pyrogen dictionary to score ligand. -
Cover MRC Case Studies FAW09
https://www2.mrc-lmb.cam.ac.uk/archive/articles/Reviewing_translation_at_the_MRC.pdf15 Apr 2015: enables automation of the test and scoring and also for a suite of. ... tests to be carried out rapidly (10-20 min), which makes it attractive. -
KWRM_A_992668_O
https://www2.mrc-lmb.cam.ac.uk/groups/wschafer/2015-3.pdf20 Oct 2015: provides a critical test for functionalimportance. Indeed, optogenetic techni-ques to artificially manipulate neuronalactivity at high spatio-temporal resolutionhave been transformative for neurosci-ence.12,13 In a similar manner, techniquesto -
Using Coot for model building into EM maps:A tutorial ...
https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/files/EM-Tutorial-Coot-PE.pdf8 Sep 2015: The test case for the tutorial is F420-reducing NiFe hydrogenase (Frh) {Allegretti:2014tz}. ... As a test case, we are going to use chain A from Frh. -
Changes in Postural Syntax Characterize Sensory Modulation and…
https://www2.mrc-lmb.cam.ac.uk/groups/wschafer/2015-5.pdf14 Aug 2015: A rank sum test comparingposture probabilities during and outside of stimulation periods shows that dorsal bends areover-represented (Fig 3C) during stimulation, as previously reported for this strain [21]. ... Hits are trigrams with significantly -
httDownloaded from rsif.royalsocietypublishing.org ResearchCite this…
https://www2.mrc-lmb.cam.ac.uk/groups/wschafer/2015-1.pdf4 Feb 2015: 2.12. Statistical analysisStandard statistical tests were performed using MATLAB func-tions. Correlation coefficients were calculated using theMATLAB function corrcoef. ... A value of þ1 indicates perfect positivecorrelation. A value of 21 indicates -
pgen.1004082 1..13
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/84_Chen_C_PlosGen_2014.pdf24 Sep 2015: indicatesp,0.01 by ANOVA, Bonferroni’s multiple comparisons test.(TIF). Figure S6 ODR-10-GFP localization in mutants expressingdefective rab proteins. ... p,0.01 (ANOVA, Bonferroni’s multiple comparisons test).(TIF). Figure S7 Deleting ufc-1 or uba-5 -
Reconstitution of a prokaryotic minus end-trackingsystem using TubRC…
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/PNAS-2015-Fink-E1845-50.pdf27 Apr 2015: To test for seeding, we followed filament formation onimmobilized TubRC complexes (Fig. -
Relocalization of STIM1 for Activation of Store-operated Ca2!Entry Is …
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/47_Ong_HL_JBC_2007.pdf24 Sep 2015: previous report (15). We wanted to test whether a model withtwo ER compartments that are functionally distinct but slowlyequilibrate with each through diffusion of Ca2! -
2168 | K. von der Malsburg et al. Molecular ...
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/93_vonderMalsburg-_K_MBC_2015.pdf11 Aug 2015: To test this directly, we used nondenaturing affinity purification to assess a possible 60S-listerin-translocon ternary complex (Figure 1E). ... To test this, we treated cultured cells with either the transla-tion elongation inhibitor cycloheximide (CHX) -
CAN-11-2008 3642..3651
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/79_Basseville_A_CanRes_2012.pdf24 Sep 2015: Statistical analysisThe Student t test was carried out for each experiment. -
doi:10.1016/j.cell.2007.01.036
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/46_Stefanovic_S_Cell_2007.pdf13 Apr 2015: To test this idea, we per-formed crosslinking analyses before and immediatelyafter incubation with membrane vesicles. ... To test this idea directly, we examined TRC40 interac-tions with Sec61b constructs appended with cyan fluores-cent protein (CFP) at -
ELIFE07975 1..21
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/94_Voorhees_RM_eLife_2015.pdf11 Aug 2015: To test this idea, scanning and engagedHA-tagged RNCs were assembled in the pres-ence of FLAG-tagged Hbs1-DN, affinity purifiedvia the FLAG tag, and tested for SRP recovery(Figure -
elife.elifesciences.org MacKinnon et al. eLife 2014;3:e01483. DOI:…
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/83_MacKinnon_AL_eLife_2014.pdf9 Sep 2015: Comparison of sensitive and resistant TMDs at multiple points along the integration pathway (i.e., at multiple nascent chain lengths) should allow us to: (1) test whether they pass through a
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