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https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/19090
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/19090{"id":19090,"date":"2020-09-03T15:00:35","date_gmt":"2020-09-03T13:00:00","guid":{"rendered":"https://www2.mrc-lmb.cam.ac.uk/?page_id=19090"},"modified":"2023-07-21T12:51:37","modified_gmt":"2023-07-21T11:51:37","slug":"anne-bertolotti-finding-clues- -
timeline | The Bacterial Cytoskeleton and other Molecular Machines
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/page12/index.html29 Apr 2024: We showed that FtsK forms a hexamer, with the DNA going through the middle of the ring. ... The middle section, after the membrane anchor, is unfolded, possibly providing a spacer to the cell wall through periplasm. -
Libcootapi’s Documentation — libcootapi documentation
https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/docs/api/html/29 Jun 2024: -
Endocytic Interactome: How Interactomes can help us design…
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/Interactomes/index.html26 Sep 2011: What is endophilin and how does it work. Research on the mechanism of endophilin in rapid vesicle endocytosis. Research on proteins involved in clathrin-coated vesicle formation. Research on membrane bending. Research on protein-lipid interactions. -
McMahon Group techniques
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/techniqs/techniqs.html26 Sep 2011: Overexpression of endocytic proteins in COS cells to test the effects of mutations in vivo. ... Liposome/lipid nanotube sedimentation assays to test lipid binding and specificity. (also immunoprecipitations, cloning, kinase assays, etc.). -
Clathrin and its interactions with AP180. AP180 is a brain enriched…
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/AP180/Clathrin.html26 Sep 2011: More experiments need to be done to test this. The platinum shadowing (from a single angle) shows that AP180 does not induce curvature in clathrin assemblies (left panel). -
Isothermal titration calorimetry to measure protein/peptide/lipid…
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/techniqs/ITC.html26 Sep 2011: Isothermal Titration Calorimetry is used to make accurate measurements of affinities and stoichiometries of interactions. It is based on fine measurements of heat changes when ligands interact -
YopJ activation by IP6
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/Black_Plague/YopJ_IP6.html26 Sep 2011: Researching the reason immune responses are sprroessed during Yersinia infections. -
McMahon Group publications
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/papers.html20 Mar 2023: An insert in the middle of the BAR domain, defines an endophilin/nadrin subfamily of BAR domains, where part of this insert forms another short amphipathic helix and also contributes to ... We then collaborated with Peter Cullen (Bristol University) to -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/23084
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/23084{"id":23084,"date":"2022-06-07T10:17:27","date_gmt":"2022-06-07T09:17:27","guid":{"rendered":"https://www2.mrc-lmb.cam.ac.uk/?p=23084"},"modified":"2022-06-07T10:17:29","modified_gmt":"2022-06-07T09:17:29","slug":"blocking-action-of-intestinal-immune
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