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8 Aug 2022: Ivana’s work included, for example, ‘Embryo stitching’ a metaphorical drawing of physical forces that play a crucial role in sculpting animal tissues/organs and a 3D mode of human haemoglobin ... Francis Crick Avenue, Cambridge Biomedical Campus,

11 Dec 2015: Search this website. LMB receive highly commended prize at Understanding Animal Research Openness Awards. ... Sketch by Mia Rosenbaum from UAR. Representatives from across the UK life science community joined Understanding Animal Research at the Wellcome

11 Jun 2012: for replicating genomes in all animals, fungi and bacteria – are able to ensure faithful DNA replication while actively excluding damaged and/or non-cognate nucleotides from the genome. ... Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge

3 Dec 2021: I’d already been a Registered Animal Technician since 1992 through the Institute of Animal Technology but this also looked like a worthy award to aim for. ... She regularly visits schools, colleges and engages online to highlight the role of an animal

21 Jul 2023: The company secured seed funding from Atlas Venture and Novartis Venture Fund, and subsequent rounds of investments have involved Schroeder Life Sciences Venture Fund, SRone, Ahren Innovation Capital, Cambridge Innovation Capital, ... Francis Crick Avenue

29 Nov 2018: Studying neuronal cell biology and how the SCN drives behaviour in humans and all animals has been made easier by the development of tools that allow rapid, reversible, and conditional control ... Search this website. 2024 MRC Laboratory of Molecular

356 of #LMB365 shows John Ou2019Neillu2019s group on an outing to visit the Corpus Clock in Cambridge. ... Ou2019Neillu2019s group on an outing to visit the Corpus Clock in Cambridge.

9 Jun 2021: within the last three years that could have a monumental impact on the replacement, reduction or refinement of the use of animals in research. ... Therefore this organoid model provides an important alternative that can replace the use of animals for the

24 Aug 2018: understood. Understanding how neuropeptide signalling operates within neuronal circuits to control complex behaviours in a simple animal like C. ... elegans will reveal principles that also apply to animals with larger brains, including humans.

30 Jun 2021: unicellular yeast to complex plants and animals. ... Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0QH, UK.

1 Aug 2012: The team’s approach, set out in a paper in Molecular Cell, may serve as a platform for similar genome-wide analyses in higher eukaryotes such as animals and plants. ... Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0QH, UK.

4 Apr 2016: Search this website. Mini-brains show great potential to replace animals in studying neurological disease. ... Mini-brains show great potential to replace animals in studying neurological disease.

4 Nov 2015: They were, for example, the first animal to have their genome sequenced, and work on worms has contributed to three Nobel prizes. ... The map of the worm’s brain was completed in Cambridge in 1986 following a decade of painstaking work by a small group

10 May 2018: Bill’s group was instrumental in developing optical approaches for measuring neural activity in living animals, and they have applied these methods to investigate how individual genes affect the activities of ... Francis Crick Avenue, Cambridge

30 Sep 2016: of the Wnt signal transduction pathway that controls normal development and tissue homeostasis in all animals. ... Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0QH, UK.

13 Mar 2017: of the animal. ... 2024 MRC Laboratory of Molecular Biology,. Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0QH, UK.

21 Jul 2023: Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0QH, UK.

13 Feb 2019: Importantly, Wnt signalling is also active in the stem cells found in most tissues in adult animals. ... 2024 MRC Laboratory of Molecular Biology,. Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0QH, UK.

3 Aug 2018: Many complex tubular organs, including kidney, lung, the intestine and several glands, form from a flat layer of cells during animal development. ... Mechanisms of organ formation are often conserved between animals, and so such analysis can inform a

21 Jul 2023: Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0QH, UK.

He is also an Honorary Senior Research Fellow in the Department of Medicine of the University of Cambridge. ... Tom obtained his PhD in Cambridge studying the molecular sequence recognition at promoter regions.

5 Sep 2011: Emotions are fundamental to animal and human behavior, but how they are encoded in the brain at the level of specific neural circuits remains poorly understood. ... In 1949 he joined Max Perutz’s MRC Unit in Cambridge. It was here that he helped solve

31 Jul 2009: Although the teams from Scripps Research and LMB were scientific competitors in earlier years, they pooled their inventions in Cambridge Antibody Technology (CAT, now MedImmune, part of AstraZeneca) to facilitate exploitation ... On July 9, 2009, the New

16 Nov 2012: The formation of tubular structures through processes collectively called tubulogenesis is a key process of organ formation in all animals. ... Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0QH, UK.

21 Jul 2023: Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0QH, UK.

11 Feb 2021: This led to a PhD at Warwick, where I got interested in biochemistry, a postdoc in Marseille, where I moved into neuroscience, and then Cambridge, where I discovered the beauty of ... C. elegans. This tiny worm allows us to study neurons in a living,

2 Jul 2021: Organ development during embryogenesis in most animals requires the transformation of simple sheets of cells into complex 3D structures. ... Search. Search this website. 2024 MRC Laboratory of Molecular Biology,. Francis Crick Avenue, Cambridge

elegans in the MRC Laboratory of Molecular Biology in Cambridge. Such long-term research could not be done today, when everybody is intent only on assured short term results and nobody ... Alzheimer’s, Huntingdon’s or Parkinson’s disease) into worms

25 May 2023: Many animals rely on smell to identify and locate objects in their surroundings and to respond appropriately. ... datasets. This project was done in collaboration with scientists at the Drosophila Connectomics group, University of Cambridge and the

and replacement of animals in research. ... Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0QH, UK. 01223 267000.

elegans/em in the MRC Laboratory of Molecular Biology in Cambridge. Such long-term research could not be done today, when everybody is intent only on assured short term results and ... Alzheimeru2019s, Huntingdonu2019s or Parkinsonu2019s disease) into

17 Jul 2019: However, it was not clear how the longer lifespan of these animals was orchestrated. ... 2024 MRC Laboratory of Molecular Biology,. Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0QH, UK.

18 Dec 2013: Using animal models of the FA disease, KJ and his team showed how the body prevents acetaldehyde from causing irreversible damage to the DNA of stem cells in the body’s ... Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0QH, UK.

14 Aug 2015: thus, enumerating an animal's complete repertoire of shape transitions would provide a. ... 2. Lehner PN. Handbook of ethological methods. 2nd ed. Cambridge ; New York: Cambridge UniversityPress; 1996.

Head-to-tail polymerisation in plants. We have recently started two different plant collaborations to explore whether the mechanism of dynamic head-to-tail polymerisation might be conserved beyond animals. ... They contain a bona fide polymerising DIX

21 Jul 2023: Search. Search this website. 2024 MRC Laboratory of Molecular Biology,. Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0QH, UK.

1 Apr 2011: They discovered a mysterious subgroup of rhomboids, which they named iRhoms, that are present in all animals (and not in single cell organisms), but lack the key catalytic signature of an ... Search. Search this website. 2024 MRC Laboratory of Molecular

13 May 2020: 13 May, 2020. Functional innovations of TBP from viruses to unicellular organisms and animals. ... 2024 MRC Laboratory of Molecular Biology,. Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0QH, UK.

26 Aug 2022: bases of neuronal computation, and his successes in linking these to decision behaviour in animals. ... Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0QH, UK.

14 Nov 2012: Understanding the basic principles of neural processing in simple animals provides critical context for studies of our own brains in health and disease. ... Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0QH, UK.

17 Apr 2012: Published on. 17 April, 2012. A group of researchers, led by Mario de Bono’s group in the LMB’s Cell Biology division, have extended our understanding of how animals respond ... These findings are significant in showing how long-lasting behavioural

24 Oct 2022: Biologists have long made use of the common code for engineering microbes, crops, and animals. ... 2024 MRC Laboratory of Molecular Biology,. Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0QH, UK.

12 Jun 2020: created from stem cells that minimises the use of animals in medical research. ... 2024 MRC Laboratory of Molecular Biology,. Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0QH, UK.

17 Dec 2010: Just as the sexes of plants and animals are controlled by genes on their sex chromosomes, Bloomfield and co-workers argued that there might be sex-determining genes to specify the ... Search. Search this website. 2024 MRC Laboratory of Molecular Biology,.

11 Jan 2019: in neurons of the SCN revealed that the animals were on slightly different cycles: astrocyte-driven rhythms were found to be approximately one hour shorter, reflecting the specific cell-autonomous features ... Francis Crick Avenue, Cambridge Biomedical

21 Jul 2023: At five to six months of age, homozygous animals develop motor symptoms characterised by severe lower limb paralysis. ... Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0QH, UK.

21 Jul 2023: Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0QH, UK.

17 Mar 2015: It was the first time a complete set of synaptic connections in the nervous system of an animal had been determined. ... Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0QH, UK.

20 Sep 2018: As well as having instinctive responses to their environment, nearly all animals can learn to associate particular sights, smells, or sounds with rewards or negative consequences. ... Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0QH,

11 Feb 2020: If we can get cells from an animal we can reprogramme them to pluripotent stem cells and use them to make brain organoids. ... They’re already seeing differences that make sense, particularly those that reflect size differences in the actual brains of