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IMS-MRL groups encompass skills in genetics, cell biology, cell signalling, neuroendocrinology, bioenergetics, human and animal physiology, experimental medicine and clinical trials. ... COVID-19. We continue to follow Government and University of

23 Feb 2024: Background and experience. I originally became interested in this field during my degree, when I studied animal behaviour. ... Sarah Grocott. Chief Animal Technician. Email: sef34 at medschl.cam.ac.uk. Team:Collaborators: DMC team and IMS mouse research

23 Feb 2024: After I graduated, I decided to stay in Cambridge and begin my career as an animal technician. ... I have a keen interest in aiding others to develop skills and understanding of best practice when working with animals in research.

23 Feb 2024: In collaboration with colleagues working in molecular epidemiology, we perform functionally-informed genetic association studies and use cell and animal models to provide deep mechanistic insights into findings from statistical genetics. ... My PhD

23 Feb 2024: I also learned new skills and techniques needed for animal work for my role with the DMC.. ... I have learned a lot about animal work and related procedures, as I had no experience in this before joining this team.

23 Feb 2024: It encompasses scientists working across the full spectrum of experimental approaches including cell biology, genetics, functional genomics, electrophysiology, animal models, basic and human neuroscience and experimental medicine. ... Together, this

23 Feb 2024: Big dataset analysis. Denise Fernandez-Twinn. Research Associate. df220 at cam.ac.uk. Project management: Animal study design and modelling; Animal licencing and compliance; Data analysis interpretation. ... Sarah Grocott. Chief Animal Technician (DMC).

23 Feb 2024: The research was led by investigators from the University of Cambridge and Pfizer, in collaboration with a diverse international team, including scientists from Novo Nordisk A/S in Denmark and the ... Cambridge, Mass., U.S.), Novo Nordisk A/S (Maaloev,

Working at the IMS-MRL. I began my journey at IMS-MRL in 2022 as a Research Animal Technician within the Disease Model Core. ... Partners. Supported by:. 2024 University of Cambridge.

His impact goes far beyond animal work to support the broader community. ... bid. In addition to shouldering these burdens, he does an excellent job navigating the often fraught landscape of animal work at the University.

23 Feb 2024: We are based on the Cambridge Biomedical Campus and our main building is embedded in the Addenbrooke’s Hospital Treatment Centre (ATC). ... We have additional spaces around the campus including further labs, space in the animal research facility and

23 Feb 2024: Between them, groups encompass skills in genetics, cell biology, cell signalling, neuroendocrinology, bioenergetics, human and animal physiology, as well as experimental medicine and clinical trials. ... Partners. Supported by:. 2024 University of

24 Feb 2024: The Merkle laboratory exploits the strengths of stem cells together with genomics, gene editing, high content screening, and animal models to model obesity. ... Partners. Supported by:. 2024 University of Cambridge.

23 Feb 2024: Students in Cambridge benefit from affiliation to a College, who provide access to a wide range of academic, social, emotional and practical support. ... I am from a town around 20 miles from Belfast, and lived there until I moved to Cambridge in 2018.

23 Feb 2024: We are based in labs within the Addenbrooke’s Treatment Centre (ATC) on the Cambridge Biomedical Campus. ... We also have other spaces around the campus including further labs and space in the animal research facility.

23 Feb 2024: Mike Murphy. Mike is based at the MRC Mitochondrial Biology Unit and is Professor of Mitochondrial Redox Biology at the University of Cambridge. ... health. Alison is based within the Wolfson Brain Imaging Centre, University of Cambridge.

These models are combined with refined neuroendocrine, behavioural and metabolic assessments in behaving animals. ... We identify druggable targets to manipulate these cells and circuits in obese animals and test the efficiency of these approaches to

23 Feb 2024: Professor John R B Perry. Chair of Molecular Endocrinology, Wellcome-MRC Institute of Metabolic Science, University of Cambridge. ... Associate Group Leader, The Gurdon Institute, University of Cambridge. Fellow and Director of Studies (Medicine),

23 Feb 2024: Our current understanding of the central control of appetite has relied heavily upon mouse models and I combine murine genetics and whole animal physiological studies to address these issues, in particular ... CRUK and National Cancer Institute (US).

23 Feb 2024: the animal kingdom, so the researchers conducted studies in mice to confirm that the MC3R pathway operates across species. ... Addenbrooke’s Charitable Trust, the National Institute for Health Research Cambridge Biomedical Research Centre, Wellcome,

23 Feb 2024: the animal kingdom, so the researchers conducted studies in mice to confirm that the MC3R pathway operates across species. ... hepatology and cancer./p pThis collaborative study was led jointly by the IMS-MRL and the Cambridge University Department of

23 Feb 2024: lines and whole animal models to better understand the pathways involved. ... Further, rodents have the advantage of being readily susceptible to genetic manipulation allowing precise alteration of specific genes and, importantly, creation of animal

23 Feb 2024: Genevieve Maul, Office of Communications, University of Cambridge. Tel: direct, 44 (0) 1223 765542, 44 (0) 1223 332300. ... 2. The Wellcome Trust is a global charitable foundation dedicated to achieving extraordinary improvements in human and animal

23 Feb 2024: The study demonstrated that the bone morphogenetic protein 8B (BMP8B), a member of the TGFβ/BMP superfamily, increases proportionally to disease stage in patients and animal models of NASH./p pBMP8B ... hepatology and cancer./p pThis collaborative study

23 Feb 2024: Thanks go here to David Rowitch’s lab (Cambridge Dept. Paediatrics) for great help with the advanced microscopy. ... the animal kingdom, so the researchers conducted studies in mice to confirm that the MC3R pathway operates across species.

23 Feb 2024: In fact, drinking its milk greatly increases the amount of calories available from an animal during its life-span. ... Giles Yeo, Principal Research Associate, director of Genomics/Transcriptomics, MRC Metabolic Diseases Unit, University of Cambridge.

23 Feb 2024: Spatial transcriptomics. Clinical Research. Whole animal physiology Cell-based research/stem cells. Team achievements. ... Partners. Supported by:. 2024 University of Cambridge.

23 Feb 2024: Thanks go here to David Rowitch’s lab (Cambridge Dept. Paediatrics) for great help with the advanced microscopy. ... the animal kingdom, so the researchers conducted studies in mice to confirm that the MC3R pathway operates across species.

23 Feb 2024: Thanks go here to David Rowitch’s lab (Cambridge Dept. Paediatrics) for great help with the advanced microscopy. ... the animal kingdom, so the researchers conducted studies in mice to confirm that the MC3R pathway operates across species.

23 Feb 2024: Institute of Metabolic Science-Metabolic Research Laboratories. MRL News. The MRL and MDU at the Cambridge Science Festival. ... March 23, 2014. The University of Cambridge Metabolic Research Laboratories (MRL) and the MRC Metabolic Diseases Unit (MDU)

23 Feb 2024: Senior author Stephen O’Rahilly, Director the MRC Metabolic Diseases Unit at the University of Cambridge. ... Cambridge, Mass., U.S.), Novo Nordisk A/S (Maaloev, Denmark) and Kymab Ltd (Cambridge, U.K.).

23 Feb 2024: resistance. Nature Genetics; 14 Nov 2016; DOI: 10.1038/ng.3714/a/em/p p1 MRC Epidemiology Unit, University of Cambridge, Cambridge, United Kingdombr / 2 Metabolic Research Laboratories, Institute of Metabolic ... Department of Public Health and Primary

Epub 2021 Dec. This collaborative (Cambridge, Heidelberg, Dublin, Aachen), research led by Guillaume Bidault, investigates the mechanisms of M2 polarisation in macrophages. ... We found that Bone Morphogenetic Protein 8B (BMP8B), increases proportionally

23 Feb 2024: His research strategies include a combination of hypothesis driven and non-biased systems approaches that make extensive use of animal models, stem cell biology, human biological samples (including induced pluripotent stem ... Partners. Supported by:.

23 Feb 2024: July 8, 2015. Scientists from the University of Cambridge Biomedical Campus recently hosted the 2. ... By integrating the expertise of these two specialized phenotyping centres, it provides a unique opportunity to learn about many of the skills required

23 Feb 2024: Disease Model Core. Senior Animal Technician. er520 at medschl.cam.ac.uk. Core Facilities. ... igz20 at medschl.cam.ac.uk. Postdoctoral Researcher. Partners. Supported by:. 2024 University of Cambridge.

23 Feb 2024: expect that they will make significant advances in knowledge in their field and act as ambassadors within the research community, helping us achieve our aim of improving human and animal health.”. ... Partners. Supported by:. 2024 University of

23 Feb 2024: This same phenomenon of linking adequate nutritional body stores to reproductive maturity is seen right across the animal kingdom, so the researchers conducted studies in mice to confirm that the MC3R ... By combining these studies with experiments in

23 Feb 2024: The MDU runs alongside the University of Cambridge Metabolic Research Laboratories, which accommodates 18 research groups with a wide range of basic, clinical and translational research expertise, and benefits from established ... Cambridge. On

23 Feb 2024: Thanks go here to David Rowitch’s lab (Cambridge Dept. Paediatrics) for great help with the advanced microscopy. ... On the other hand, our single homozygous null proband was severely obese and in MC3R KO mice there is some increase in fat mass –

23 Feb 2024: 12.40 Dr. Sam Virtue, Institute of Metabolic Science, Cambridge. “Metabolic Flexibility links adipose dysfunction to metabolic disease”. ... 13.40 Dr. Shuai Chen, Model Animal Research Center of Nanjing University.

23 Feb 2024: resistance. Nature Genetics; 14 Nov 2016; DOI: 10.1038/ng.3714/a/em/p p1 MRC Epidemiology Unit, University of Cambridge, Cambridge, United Kingdombr / 2 Metabolic Research Laboratories, Institute of Metabolic ... Science, University of Cambridge,

23 Feb 2024: Cambridge. The finding may explain why Labrador retrievers are more likely to become obese than dogs of other breeds. ... prone to being overweight in comparison to other breeds,” explains first author Dr Eleanor Raffan from the University of Cambridge.

In collaborative studies, combining human genetics, cellular work and studies in animals and humans, we found that the Semaphorin3-Neuropilin-PlexinA (S3NPA) family of genes control hypothalamic development and that the ... Email: av330 at

23 Feb 2024: She also works as an honorary diabetes in pregnancy physician and chemical pathologist at Cambridge University Hospitals NHS Foundation Trust. ... Antibodies that bind and activate the insulin receptor in a different way to insulin are able to activate

23 Feb 2024: She also works as an honorary diabetes in pregnancy physician and chemical pathologist at Cambridge University Hospitals NHS Foundation Trust. ... Thanks go here to David Rowitch’s lab (Cambridge Dept. Paediatrics) for great help with the advanced

23 Feb 2024: In a study published today in the journal Nature Communications, researchers at the University of Cambridge gave participants an all-you-can-eat buffet of chicken korma – a popular type of ... future. Professor Sadaf Farooqi from the Wellcome

15 Feb 2024: IMS:. 1.2.1 Molecular and cellular based experimental data. 1.2.2 Physiological data from animal models. ... An increasing number of teams use electronic notebooks (LabArchives). 1.3.2 Physiological data from animal models.

23 Feb 2024: Antibodies that bind and activate the insulin receptor in a different way to insulin are able to activate mutant receptors and restore glucose tolerance in animal models. ... Partners. Supported by:. 2024 University of Cambridge.

23 Feb 2024: Real-World Evidence of the Cambridge Hybrid Closed-Loop App With a Novel Real-Time Continuous Glucose Monitoring System. ... Fetal and postnatal outcomes in offspring after intrauterine metformin exposure: A systematic review and meta-analysis of animal