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The Vendruscolo Laboratory
www-vendruscolo.ch.cam.ac.uk/28 Feb 2023: By analyzing proteome-wide mass spectrometry data of Caenorhabditis elegans, however, we show that the levels of about three-quarters of the nearly 4,000 proteins analyzed in adult animals are -
Delivery of Native Proteins into C. elegans Using a Transduction…
www-vendruscolo.ch.cam.ac.uk/perni2017sr.pdf15 Dec 2017: Centre for Misfolding Diseases, Department of Chemistry, University of Cambridge, Cambridge, CB2 1EW, UK. ... 3. Jaenisch, R. Transgenic animals. Science 240, 1468–1474 (1988). 4. Jucker, M. -
ALS mutations in FUS cause neuronal dysfunctionand death in ...
www-vendruscolo.ch.cam.ac.uk/murakami12hmg.pdf15 Jan 2012: was significantly greater than that in N2 and WT-FUS animals(P , 0.001). ... At 8 days of age,P525L and FUS501 animals are obviously smaller and pale. -
RSC_IB_C0IB00149J 1..6
www-vendruscolo.ch.cam.ac.uk/kohlhoff11ib.pdf15 Jan 2012: model animal systems, such as mice, fish, or primates. In the case of fruit flies, standard assays. ... a Department of Chemistry, University of Cambridge, Cambridge, UK.E-mail: mv245@cam.ac.uk. b Department of Genetics, University of Cambridge, Cambridge -
Multistep Inhibition of α-Synuclein Aggregation and Toxicity in Vitro …
www-vendruscolo.ch.cam.ac.uk/perni2018acb.pdf23 Sep 2018: Dobson,†,‡. †Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, United Kingdom‡Centre for Misfolding Diseases, Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, United KingdomDepartment of Experimental -
The Vendruscolo Laboratory
www-vendruscolo.ch.cam.ac.uk/research.html28 Feb 2023: By analyzing proteome-wide mass spectrometry data of Caenorhabditis elegans, however, we show that the levels of about three-quarters of the nearly 4,000 proteins analyzed in adult animals are -
A tau homeostasis signature is linked with the cellular and regional…
www-vendruscolo.ch.cam.ac.uk/fu2019nn.pdf18 Dec 2018: 4Centre for Misfolding Diseases, Department of Chemistry, University of Cambridge, Cambridge, UK. ... Data are presented as mean s.e.m. In c, d, f, n = 6 animals, 2 sections per animal; sections with no MC1+ neurons were removed from further analysis, -
Combinations of Vitamin A and Vitamin E Metabolites Confer Resilience …
www-vendruscolo.ch.cam.ac.uk/Joshi-2023-ACSCN.pdf2 Mar 2023: Xiaoting Yang Centre for Misfolding Diseases, Departmentof Chemistry, University of Cambridge, Cambridge CB21EW, U.K. ... Johnny Habchi Centre for Misfolding Diseases, Departmentof Chemistry, University of Cambridge, Cambridge CB21EW, U.K. -
A natural product inhibits the initiation of α-synuclein aggregation…
www-vendruscolo.ch.cam.ac.uk/perni2017pnas-ee.pdf19 Jan 2017: Dobsona,2. aDepartment of Chemistry, University of Cambridge, Cambridge CB2 1EW, United Kingdom; bUniversity Medical Centre Groningen, European ResearchInstitute for the Biology of Aging, University of Groningen, Groningen 9713 AV, The ... Netherlands; -
however, excess glucose can lead to an increased flux ...
www-vendruscolo.ch.cam.ac.uk/vendruscolo08ncb.pdf30 Sep 2009: Immunohistochemical analysis of brain samples from animals that had received Thiamet-G by the oral administration route revealed a similar picture of specific suppres-sion of tau phosphorylation. ... Michele Vendruscolo is in the Department of Chemistry,
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