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doi:10.1016/j.ceb.2003.11.005
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/cocb%202003.pdf27 Nov 2003: In fungi and animal cells, but apparently not in plants, thedivision plane is first defined by a ring assembled fromseptin filaments [22,23]. ... Some of the cytoskeleton proteins involved in cytokinesis. (a)Representation of a section through an animal -
x15959u064
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Reim_Brose2001.pdf17 Mar 2003: In the present study, we use double deletion mutant‖ Present address: MRC Laboratory of Molecular Biology, Neurobiol-mice to demonstrate that CPXs are important positiveogy Division, Hills Road, Cambridge CB2 2QH, ... animals) (Figure 6B). Thus, -
doi:10.1016/j.cell.2006.03.035
https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/16647110.pdf14 Jun 2006: regulation of the p85 subunit that is observed in heterozy-. gous animals (Brachmann et al., 2005). ... Animals were fasted to normalize. blood glucose levels and then challenged with insulin. -
A Large Particle Associated with the Perimeter of the ...
https://www2.mrc-lmb.cam.ac.uk/groups/nu/pdf/jcb82.pdf5 Jul 2010: P. N. T. UNWIN and R. A. MILLIGANDepartment of Structural Biology, Stanford University Medical School, Stanford, California 94305; andMedical Research Council Laboratory of Molecular Biology, Cambridge, England. ... J. Microscopie. 6:371-390. 31. Watson, -
Amphiphysin is necessaryfor organization of the…
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/DroxAmph.pdf9 Nov 2001: 1Department of Genetics, University of Cambridge, Cambridge CB2 3EH, UK; 2Department of Biochemistry, Universityof Cambridge, Cambridge CB2 1QW, UK; 3Medical Research Council Laboratory of Molecular Biology, Cambridge CB22QH, UK; 4Multi-Imaging -
Structure of a cholinergic cell membraneNigel Unwina,1 Edited by ...
https://www2.mrc-lmb.cam.ac.uk/groups/nu/pdf/pnasS22.pdf4 Nov 2022: Author affiliations: aMedical Research Council Laboratoryof Molecular Biology, CB2 0QH, Cambridge, UnitedKingdom. ... This could be a common occur-rence, since cholesterol typically constitutes 30–40 mol % ofthe total lipids in animal cell membranes (35 -
Biallelic Variants in ASNA1, Encoding a Cytosolic Targeting Factor of …
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/CircGen_2019.pdf1 Dec 2019: Medical Research Council Laboratory of Molecular Biology, Cambridge Biomedical Campus, United Kingdom (M.H.K., R.S.H.). ... Animal models for ASNA1-mediated TA protein insertion related genes …………….….34. SUPPLEMENTAL FIGURES. -
GB-9-7-229-Amos_9.qxd
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/gb-2008-9-7-229.pdf4 Aug 2008: 2008 BioMed Central Ltd. GGeennee oorrggaanniizzaattiioonn aanndd eevvoolluuttiioonnaarryy hhiissttoorryyGenes for tektins are found throughout the animal kingdom. ... animals, including mammals. Dense fibers do not occur in. cilia, or in the flagella of -
Membrane transport between compartments in eukary-otic cells requires …
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Dynaminreview2004.pdf2 Feb 2004: Figure 1 | Dynamin-superfamily members in animals and plants. We have subdivided thedynamin superfamily into ‘classical dynamins’ and ‘dynamin-related proteins’. ... Mitofusin/Fzo1 Mitochondrial outer membrane Mitochondrial fusion and division. -
IntroductionThe endosomal system functions as an internal…
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/SNX2Cullen2005.pdf17 Jan 2006: Biology, Hills Road, Cambridge CB2 2QH, UK3Cell Microscopy Center, Department of Cell Biology and Institute for Biomembranes, University Medical Centre Utrecht, Utrecht, The Netherlands4Signalling Programme, The Babraham Institute, Babraham Hall, -
Dynamin architecture—from monomer to polymer
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/dynaminreviewCOSBILow2010.pdf21 Oct 2010: evolutionary kingdoms. Address. MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 0QH,. ... 2010 Elsevier Ltd. All rights reserved. DOI 10.1016/j.sbi.2010.09.011. IntroductionDynamins form a large family of proteins of great -
ANALYSIS Integrating molecular and network biologyto decode…
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Schmid_Nature2007.pdf22 Aug 2007: 2a)7,8,23,24. 1MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 0QH, UK. ... We observe that most participatingproteins are conserved in the animal kingdom (Table 1 and Supple-mentary Information Part 4). -
Supplementary Text & Figs
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Schmid_Nature2007Sup.pdf22 Aug 2007: Eva M. Schmid and Harvey T. McMahon. MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 0QH, UK. ... observed that conservation of endocytic proteins through the animal kingdom was high. -
The structure of human thyroglobulin
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/TG_Nature2020.pdf31 Jan 2020: 1MRC Laboratory of Molecular Biology, Cambridge, UK. 2Jožef Stefan Institute, Ljubljana, Slovenia. -
pone.0052401 1..15
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Papers/Podosome2012/journal.pone.0052401.pdf10 Jan 2013: Addenbrooke’s Hospital, Cambridge, United Kingdom. Abstract. Cell motility, adhesion and phagocytosis are controlled by actin and membrane remodelling processes. ... anti-Endophilin1 and 2 antibodies (ZYMED Laboratories, Invi-. trogen respectively). -
doi:10.1016/j.cub.2004.09.077
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Snx1PeteCullen2004/Snx1PeteCullen2004.pdf23 Nov 2004: Mol. Biol. Cell 15, 721–733.for Medical Research, Cambridge, UK). Secondary antibodies conju- 6. ... Mol.Cell. Biol. 18, 7278–7287.Matthew Seaman (Cambridge Institute for Medical Research, Cam-. -
doi:10.1016/j.biocel.2008.08.010
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/cytomotive2008Lowe.pdf17 Sep 2008: AmosRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 0QH, UK. ... Mol Microbiol2004;52:385–98. ggert US, Mitchison TJ, Field CM. Animal cytokinesis: from parts list to mechanisms.Annu Rev Biochem 2006;75:543–66. -
740 Research Paper Calcium triggers calcineurin-dependent synaptic…
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Marks_McMahon1998.pdf21 Mar 2003: Address: MRC Laboratory of Molecular Biology,Hills Road, Cambridge CB2 2QH, UK. ... Also we would like to thankTheresa Langford and the animal unit staff for their support. -
, 130081, published 7 August 20133 2013 Open Biol. ...
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Papers/Open%20Biol.-2013-TakedaCombined.pdf25 Sep 2013: Biology, Francis Crick Avenue, Cambridge CB2. 0QH, UK. Electronic supplementary material is available. ... In yeast and in animal cells,PI(4,5)P2 localizes to the cleavage furrow and plays importantregulatory roles in cytokinesis [29]. -
elifesciences.org van den Ent et al. eLife 2014;3:e02634. DOI: ...
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/mrebdouble2014.pdf6 Jun 2014: 1Structural Studies Division, Medical Research Council - Laboratory of Molecular Biology, Cambridge, United Kingdom; 2Protein and Nucleic Acid Chemistry Division, Medical Research Council - Laboratory of Molecular Biology, Cambridge, United Kingdom. -
cdf672 6935..6943
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/ParM%20EMBO%20F-actin%202002.pdf30 Dec 2002: MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB22QH, UK and 1Department of Biochemistry and Molecular Biology,University of Southern Denmark, DK-5230 Odense M, Denmark. ... Theaddition of new subunits to the ends of laments maymove the -
doi:10.1016/j.molcel.2004.08.004
https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/15350214.pdf24 Sep 2004: al., 2000; Verbsky et al.,Cambridge CB2 1PD2002; York et al., 1999). ... In addition, animal IP3-3Ksvesicular trafficking, channel regulation, cell prolifera- also have a conserved Ca2/Calmodulin (CAM) bindingtion, and a variety of nuclear functions -
Abstract_Book_HMM_v2
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/conferences/JM_Abstract_Book.pdf15 Sep 2011: 09:50-10:20 Harvey McMAHON (Cambridge, United Kingdom). Molecular determinants of membrane fusion and fission Déterminants moléculaires de la fusion et de la fission des membranes. ... Hills Road, UK-Cambridge CB2 0HQ, United Kingdom 2 Department of -
pnas201206839 17424..17429
https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/23045692.pdf21 Nov 2012: Lamersa, Roger L. Williamsa,2, and Juan Martin-Serranob. aLaboratory of Molecular Biology, Medical Research Council, Cambridge CB2 0QH, United Kingdom; and bDepartment of Infectious Diseases, King’s CollegeLondon School of ... Nat Cell Biol -
Amos&Schlieper.indd
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/Amos%26Schlieper.pdf16 Nov 2005: MICROTUBULES AND MAPs. By LINDA A. AMOS AND DANIEL SCHLIEPERMRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 2QH, UK. -
Structure of a Bacterial Dynamin-like Protein Lipid Tube Provides a…
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/cell%202009%20dynamin.pdf19 Dec 2009: Low,1,2, Carsten Sachse,1 Linda A. Amos,1 and Jan Löwe1,1MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 0QH, UK2Present address: School of Crystallography, Birkbeck College, Malet ... which is expected given the high level of divergence -
The structure of bactofilin filaments reveals their mode of membrane…
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/Deng2019Natmicro.pdf26 Aug 2019: Articleshttps://doi.org/10.1038/s41564-019-0544-0. 1MRC Laboratory of Molecular Biology, Cambridge, UK. 2These authors contributed equally: Xian Deng, Andres Gonzalez Llamazares. -
Qrb1300006 1..40
https://www2.mrc-lmb.cam.ac.uk/groups/nu/pdf/qrb13.pdf30 Jul 2013: Nicotinic acetylcholinereceptorandthestructuralbasisofneuromuscular transmission:insightsfromTorpedopostsynapticmembranes. Nigel UnwinMRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge CB2 0QH, UK. ... Avenue, Cambridge CB2 0QH, UK. Tel: -
Prokaryotic cytoskeletons: protein filaments organizing small cells
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/nrmicro.2017.153.pdf18 Jan 2018: Medical Research Council Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge CB2 0QH, UK. ... For example, the role of the actin cytoskeleton in determining the shape of many animal cells is well established. -
TTC5 mediates autoregulation of tubulin via mRNA degradation
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/Science_2019.pdf19 Nov 2019: Mitchison2, Ramanujan S. Hegde1‡ 1MRC Laboratory of Molecular Biology, Cambridge CB2 0QH, UK. ... doi:10.1146/annurev-biochem-060815-014528 Medline. 20. S. L. Prosser, L. Pelletier, Mitotic spindle assembly in animal cells: A fine balancing act. -
elifesciences.org Szwedziak et al. eLife 2014;3:e04601. DOI:…
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/FtsZ_Piotr_eLife_2014.pdf31 Dec 2014: Structural Studies Division, MRC Laboratory of Molecular Biology, Cambridge, United Kingdom. ... When bacterial and animal cells divide, they must constrict their membrane inwards to split a single cell into two. -
Tumour prevention by a single antibody domaintargeting the…
https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/17568777.pdf22 Jul 2007: Tomoyuki Tanaka, Roger L Williamsand Terence H Rabbitts. MRC Laboratory of Molecular Biology, Hills Road, Cambridge, UK. ... R Berks for animal experiments, E Obayashi forpRKHISTEV and TEV protease, and R Grenfell for cell sorting,and also thank Elena -
PII: S1097-2765(02)00515-4
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/SMC%20cohesin%20paper%202002.pdf19 Apr 2002: In yeast, most cohesin remains associated with chro-Cambridge CB2 2QHmosomes until metaphase but dissociates at the onsetUnited Kingdomof anaphase, when cohesion is dissolved. ... tute of Technology, Cambridge, Massachusetts 02139. C-terminal domains -
Dynamic Filaments of the Bacterial Cytoskeleton
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/annrev2006.pdf19 Apr 2006: Michie and Jan LöweMedical Research Council Laboratory of Molecular Biology, Cambridge CB2 2QH,UK; email: kmichie@mrc-lmb.cam.ac.uk, jyl@mrc-lmb.cam.ac.uk. -
Tyrosine Residues in Phospholipase C�2 Essential for the…
https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/11606584.pdf20 Apr 2002: London SW3 6JB, United Kingdom, the ‡Medical Research Council Laboratory ofMolecular Biology, Medical Research Council Centre, Hills Rd., Cambridge CB2 2QH, United Kingdom, and theDepartment of Anatomy and Developmental Biology, University -
nrm2162.indd
https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/17450176.pdf14 Jun 2007: The components of the multivesicular body (MVB) pathway are ancient and predate the divergence of plants and animals more than one billion years ago127,128. ... 3b). Vps36 has an ancient origin and was probably present in the common ancestor of plants -
Doc2b Is a High-Affinity Ca2+ Sensor forSpontaneous Neurotransmitter…
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Papers/GroffenScience2010.pdf30 Apr 2010: 2Medical Research Council(MRC) Laboratory of Molecular Biology, Hills Road, Cambridge,CB2 0QH, UK. ... Generation of knock-out mice Animals were housed and bred according to institutional, Dutch, and US governmental guidelines. -
PHAGOCYTES, GRANULOCYTES, AND MYELOPOIESIS PSTPIP2 deficiency in mice …
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Papers/Blood-2012-Chitu-3126-35.pdf12 Oct 2012: Cornell University, Weill Hall, Ithaca, NY; and 5Medical ResearchCouncil Laboratory of Molecular Biology, Hills Road, Cambridge, United Kingdom. ... pathogen-free conditions in a barrier facility of the Albert Einstein College ofMedicine Animal Institute, -
Molecular mechanism and physiological functions of clathrin-mediated…
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Papers/McMahon%20NRMB%202011.pdf19 Jul 2011: Medical Research Council Laboratory of Molecular Biology, Hills Road, Cambridge CB2 0QH, UK.e-mails: hmm@mrc-lmb.cam.ac.uk; eboucrot@mrc-lmb.cam.ac.ukdoi:10.1038/nrm3151.
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