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Salt chemosensation in worms linked to human deafness - MRC…
https://www2.mrc-lmb.cam.ac.uk/salt-chemosensation-in-worms-linked-to-human-deafness/31 Jan 2013: Transmembrane channel-like (TMC) genes encode a conserved family of predicted membrane proteins in animals. ... More generally, the study suggests that TMCs comprise a new family of ion channels that may participate in a range of sensory transduction -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/33025
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/33025nnnn. Many animals rely on smell to identify and locate objects in their surroundings and to respond appropriately. -
How eating feeds into the body clock - MRC Laboratory of Molecular…
https://www2.mrc-lmb.cam.ac.uk/how-eating-feeds-into-the-body-clock/25 Apr 2019: The researchers went on to show that if insulin is provided at the wrong biological time, when animals would normally be resting, it disrupts normal circadian rhythms: reducing their amplitude. ... Francis Crick Avenue, Cambridge Biomedical Campus, -
Tripodi Lab
https://www2.mrc-lmb.cam.ac.uk/groups/tripodi/feed/3 May 2022: mrc-lmb.cam.ac.uk/groups/tripodi/?p=127 I am a MB PhD student at the University of Cambridge, School of Clinical Medicine. ... I graduated in Italy for my BSc, I then moved to Cambridge […] pThe main aim of my research is to understand how the brain -
Mark Bretscher's Publications List - MRC Laboratory of Molecular…
https://www2.mrc-lmb.cam.ac.uk/mark-bretschers-publications-list/21 Jul 2023: How animal cells move. Scientific American, 255, 72-90 (1987). Francis Crick, Obituary, in The Independent, August 3. ... Search. Search this website. 2024 MRC Laboratory of Molecular Biology,. Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/11746
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/1174659","modified_gmt":"2021-07-19T11:48:59","slug":"lmbs-challenge-project-with-cambridge-academy-for-science-and-technology","status":"publish","type":"post","link":"https://www2.mrc-lmb.cam.ac.uk/ ... lmbs-challenge-project-with-cambridge-academy-for-scien -
Understanding timekeeping in an intertidal marine crustacean - MRC…
https://www2.mrc-lmb.cam.ac.uk/understanding-timekeeping-in-an-intertidal-marine-crustacean/27 Sep 2013: They were interested in whether these animals are driven by a dedicated internal tidal clock or are controlled by a system based on a modified 24-hour circadian clock. ... Marine animals that live on the coast are very important ecologically and -
Madeline Lancaster wins the 2015 3Rs Prize for 3D tissue models - MRC …
https://www2.mrc-lmb.cam.ac.uk/madeline-lancaster-wins-the-2015-3rs-prize-for-3d-tissue-models/29 Feb 2016: The 3Rs Prize is part of its strategy to recognise excellence in science which minimises animal use or improves animal welfare. ... The suitability of animal models in studying brain development and disease can be limited, as the brains of commonly used -
LMB welcomes over 2500 visitors to an action-packed Open Day - MRC…
https://www2.mrc-lmb.cam.ac.uk/lmb-welcomes-over-2500-visitors-to-an-action-packed-open-day/31 Jul 2023: People dressed up as animal technicians and experienced how we make up enriched mouse cages. ... Search. Search this website. 2024 MRC Laboratory of Molecular Biology,. Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0QH, UK. -
2022 Francis Crick Lecture to be given by Catherine Dulac - MRC…
https://www2.mrc-lmb.cam.ac.uk/2022-francis-crick-lecture-to-be-given-by-catherine-dulac/27 Oct 2022: Social interactions are essential for animals to survive, reproduce and raise their young. ... of social behaviour circuits, how is the function of these circuits different in males and females and how are they modulated by the animal physiological status -
Network control principles predict neuron function in the C. elegans…
https://www2.mrc-lmb.cam.ac.uk/network-control-principles-predict-neuron-function-c-elegans-connectome/19 Oct 2017: The nematode worm Caenorhabditis elegans, still the only animal for which the entire connectome has been described, illustrates the problem. ... Remarkably, the control theory predictions were confirmed, with ablations of neurons required for full -
Student prizes awarded for outstanding doctoral research - MRC…
https://www2.mrc-lmb.cam.ac.uk/student-prizes-awarded-for-outstanding-doctoral-research/28 Oct 2019: said. Going forward, he wants to continue investigating the fly brain. “There is a lot we don’t know about this small animal, and we can use it to ask questions ... that we have no hope of answering in larger animals,” added Alex. -
Lights, Crafts and Charity: Christmas at the LMB - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/lights-crafts-and-charity-christmas-at-the-lmb/22 Dec 2020: They sold a wide-assortment of home-made items by the group and other members of the LMB, including crocheted Christmas pudding tree-decorations, animal bookmarks and pocket pals, handmade cards ... Francis Crick Avenue, Cambridge Biomedical Campus, -
Engaging with the public while social distancing - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/engaging-with-the-public-while-social-distancing/14 Apr 2020: LMB’s participants – Nathan James from Venki Ramakrishnan’s group, Xiaohan Li from Madan Babu’s group, and Jennifer Roe, an animal technician in the Biological Services Group – showcased structural biology, ... Francis Crick Avenue, Cambridge -
A synthetic molecule that can restore lost connections in the brain - …
https://www2.mrc-lmb.cam.ac.uk/a-synthetic-molecule-that-can-restore-lost-connections-in-the-brain/28 Aug 2020: Published on. 28 August, 2020. Summary of CPTX impact upon injection in animal models of Ataxia, Alzheimer’s Disease and spinal cord injury. ... 2024 MRC Laboratory of Molecular Biology,. Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 -
2016 César Milstein Lecture to be given by Yoshinori Ohsumi - MRC…
https://www2.mrc-lmb.cam.ac.uk/2016-milstein-lecture-given-yoshinori-ohsumi/2 Sep 2016: His work showed that autophagy is one of the most basic functions in cells of many plants and animals. ... Search this website. 2024 MRC Laboratory of Molecular Biology,. Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0QH, UK. -
Pathway behind pathogenic mechanism of tuberculosis identified - MRC…
https://www2.mrc-lmb.cam.ac.uk/pathway-behind-pathogenic-mechanism-of-tuberculosis-identified/24 Jun 2022: Lalita Ramakrishnan, Group Leader in the LMB’s Cell Biology Division and Head of the University of Cambridge’s Molecular Immunity Unit (housed at the LMB), has previously shown that excess ... M. marinum is a natural pathogen of cold-blooded animals -
Madeline Lancaster explains brain organoids to The Times - MRC…
https://www2.mrc-lmb.cam.ac.uk/madeline-lancaster-explains-brain-organoids-to-the-times/8 Oct 2019: us apart from animals (story behind paywall). ... Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0QH, UK. -
César Milstein Lecture to be given by Hans Clevers - MRC Laboratory…
https://www2.mrc-lmb.cam.ac.uk/cesar-milstein-lecture-to-be-given-by-hans-clevers/23 Nov 2021: Organoids are now widely used in basic and applied biomedicine, occupying a niche between ‘classical’ 2D cell lines and animal experimentation. ... Search this website. 2024 MRC Laboratory of Molecular Biology,. Francis Crick Avenue, Cambridge -
Decoding how detection of odours leads to diverse behaviours in flies …
https://www2.mrc-lmb.cam.ac.uk/decoding-how-detection-of-odours-leads-to-diverse-behaviours-in-flies/17 Jun 2019: into the innate odour processing pathway of a behaviourally complex animal, the vinegar fly. ... Importantly, the researchers found that the same neuron type drove the same response in different animals. -
2016 John Kendrew Lecture to be given by Bonnie Bassler - MRC…
https://www2.mrc-lmb.cam.ac.uk/2016-john-kendrew-lecture-given-bonnie-bassler/17 Oct 2016: Indeed, our most potent quorum sensing modulators protect animals from quorum-sensing-mediated killing by pathogenic bacteria and prevent biofilm formation. ... From 1981-1987 he was President of St John’s College, Oxford. He died in Cambridge on 23rd -
Potential new target for Asthma treatment discovered - MRC Laboratory …
https://www2.mrc-lmb.cam.ac.uk/potential-new-target-for-asthma-treatment-discovered/3 Mar 2010: The new cell type was named nuocyte because these cells are the main source of IL-13, and nu is the 13th letter of the Greek alphabet. ... Search. Search this website. 2024 MRC Laboratory of Molecular Biology,. Francis Crick Avenue, Cambridge Biomedical -
McMahon Group publications
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/papers.html20 Mar 2023: Pacsin) functions at the interface between membrane and the actomyosin contractile ring during cytokinesis of animal cells. ... Painting by an art student, Alex McCuish from Hills Road Sixth Form College, Cambridge UK, of the protein interaction network -
Rebecca Taylor: A worm's eye view of stress and ageing - MRC…
https://www2.mrc-lmb.cam.ac.uk/rebecca-taylor-a-worms-eye-view-of-stress-and-ageing/23 Sep 2019: What’s interesting is that the effect of this constitutive stress signal is to change the way an animal ages,” says Rebecca. ... In good conditions, it tells the animal to put all its efforts into reproduction. -
2018 Francis Crick Lecture to be given by Gero Miesenböck - MRC…
https://www2.mrc-lmb.cam.ac.uk/2018-francis-crick-lecture-to-be-given-by-gero-miesenbock/17 Oct 2018: was the first to demonstrate that the behaviour of these animals could be remote-controlled. ... Search. Search this website. 2024 MRC Laboratory of Molecular Biology,. Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0QH, UK. -
William Schafer elected Fellow of Royal Society - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/william-schafer-elected-fellow-of-royal-society/29 Apr 2020: In the course of this work he has also introduced new methods for detecting and recording the activities of neurons in living animals and for quantitatively defining the effects of genetic ... Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge -
Watching neurons transmit visual information - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/watching-neurons-transmit-visual-information/21 May 2013: This is the first time that it has been possible to observe the activity of hundreds of synapses in a living animal. ... Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0QH, UK. -
Raphin 1 and phosphatase inhibitors technology (2018) - MRC…
https://www2.mrc-lmb.cam.ac.uk/research/technology-transfer/recent-technology-transfer-initiatives/raphin1-2018/21 Jul 2023: Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0QH, UK. -
2021 Max Perutz Lecture to be given by David Baker - MRC Laboratory…
https://www2.mrc-lmb.cam.ac.uk/2021-max-perutz-lecture-to-be-given-by-david-baker/20 Apr 2021: Max first arrived in Cambridge in 1936 as a research student to study X-ray crystallography at the Cavendish Laboratory under J. ... Search. Search this website. 2024 MRC Laboratory of Molecular Biology,. Francis Crick Avenue, Cambridge Biomedical Campus, -
LMB’s Challenge Project with Cambridge Academy for Science and…
https://www2.mrc-lmb.cam.ac.uk/lmbs-challenge-project-with-cambridge-academy-for-science-and-technology/23 Mar 2018: Search this website. LMB’s Challenge Project with Cambridge Academy for Science and Technology. ... LMB’s Challenge Project with Cambridge Academy for Science and Technology. Published on. -
Neonatal Mouse Anaesthetisation Mould Request Form - MRC Laboratory…
https://www2.mrc-lmb.cam.ac.uk/research/technology-transfer/neonatal-mouse-anaesthetisation-mould-request-form/21 Jul 2023: Search. Search this website. 2024 MRC Laboratory of Molecular Biology,. Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0QH, UK. -
Baum Lab
https://www2.mrc-lmb.cam.ac.uk/groups/baum/feed/3 Apr 2024: There, he started his work to address cell division in different Archaea, which is now continued at the MRC Laboratory of Molecular Biology, Cambridge (UK) using Super-Resolution Microscopy techniques./divul ... He returned to the UK in 2001, when he set -
LMB welcomes Emmanuel Derivery as new Group Leader - MRC Laboratory…
https://www2.mrc-lmb.cam.ac.uk/lmb-welcomes-emmanuel-derivery-new-group-leader/17 Nov 2016: to how they function in the whole animal during development.”. ... Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0QH, UK. -
The smell of food ‘wakes up’ the zebrafish visual system - MRC…
https://www2.mrc-lmb.cam.ac.uk/the-smell-of-food-wakes-up-the-zebrafish-visual-system/11 Jul 2013: retina and observe the activity of synapses as the animal responded to different visual stimuli and smells. ... The same connections between the nose and retina occur in other animals, including humans. -
Perutz, Steitz and Southgate Prizes awarded to LMB students, postdocs …
https://www2.mrc-lmb.cam.ac.uk/perutz-steitz-and-southgate-prizes-awarded-to-lmb-students-postdocs-and-staff/20 Oct 2023: Jasmine, who is an animal technician at LMB and Ares is someone who goes the extra mile to understand what the researchers require in their experimental protocols, making it possible for ... His commitment and support have significantly improved the -
Identification of pathway that enables resistance to tuberculosis -…
https://www2.mrc-lmb.cam.ac.uk/identification-of-pathway-that-enables-resistance-to-tuberculosis/29 Sep 2022: A new study from Lalita Ramakrishnan, Group Leader in the LMB’s Cell Biology Division and Head of the Molecular Immunity Unit of the Cambridge Institute of Therapeutic Immunology and Infectious ... Diseases (CITIID) of the University of Cambridge, has -
How timing in early brain development sets humans apart from apes -…
https://www2.mrc-lmb.cam.ac.uk/how-timing-in-early-brain-development-sets-humans-apart-from-apes/24 Mar 2021: Asking what sets us apart from other animals is a fundamental question with a simple answer: our brains, and, most strikingly, their size. ... The brain is the feature that most clearly sets humans apart from other animals and its increased size is the -
Gerry Rubin: Looking Back - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/share-your-memories/gerry-rubin/31 Mar 2021: Perhaps my most vivid memory from my first year was of being joined by Michael Fuller and members of the Cambridge fire brigade at 10 PM on Xmas eve 1971 after ... In 1982, Allan Spradling and I developed methods for making transgenic Drosophila, the -
The LMB welcomes Marta Zlatic as a new Group Leader - MRC Laboratory…
https://www2.mrc-lmb.cam.ac.uk/the-lmb-welcomes-marta-zlatic-as-a-new-group-leader/2 Dec 2019: A main aim of Marta’s group’s work is to understand how neuronal circuitry enables animals to learn and to select an appropriate response based on the learnt information. ... Marta completed her PhD and postdoctoral work at the University of Cambridge -
Crystallisation and X-ray - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/research/scientific-facilities-and-support-services/crystallisation-and-x-ray/21 Jul 2023: Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0QH, UK. -
Alan Fersht and Marta Zlatic win Royal Society Medals - MRC…
https://www2.mrc-lmb.cam.ac.uk/alan-fersht-and-marta-zlatic-win-royal-society-medals/4 Aug 2020: of Organic Chemistry at the University of Cambridge, and simultaneously headed the MRC Centre for Protein Engineering from 1988 to 2010, next door to the old LMB building. ... Previously, she was a Research and Teaching Fellow at Trinity College and the -
Chris Tate and Marta Zlatic elected to EMBO membership - MRC…
https://www2.mrc-lmb.cam.ac.uk/chris-tate-and-marta-zlatic-elected-to-embo-membership/7 Jul 2020: A main aim of Marta’s group’s work is to understand how neuronal circuitry enables animals to learn and select actions, as well as to investigate the structural changes in ... Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0QH, UK. -
A connection between stress detection and lifestyle decisions in…
https://www2.mrc-lmb.cam.ac.uk/a-connection-between-stress-detection-and-lifestyle-decisions-in-worms/24 Nov 2020: and they found that these neurons naturally produced XBP-1s when the worm was starved, suggesting that this might be a part of the animal’s response to low nutrient conditions. ... Search this website. 2024 MRC Laboratory of Molecular Biology,. Francis -
Celia Milstein (1928 – 2020) - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/alumni/celia-milstein-1928-2020/21 May 2021: Celia was a Principal Scientific Officer at ARC Institute of Animal Physiology, Babraham and had been a very active member of the Cambridge academic and social scenes for many decades. ... Cambridge and, of these, none have had more medical consequences -
Trim-Away™ (2017) - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/research/technology-transfer/recent-technology-transfer-initiatives/trim-away-2017/21 Jul 2023: Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0QH, UK. -
“The LMB provides an unsurpassed environment for both new ...
https://www2.mrc-lmb.cam.ac.uk/?wpdmdl=1885218 Jan 2021: elegans is first animal to have genome sequenced. 2017-2018: Structures of tau filaments from Alzheimer’s and. ... 1986: C. elegans is the first animal to have its. entire nervous system mapped. -
Chomsky and the platypus
https://www2.mrc-lmb.cam.ac.uk/groups/tripodi/2020/11/24/chomsky-and-the-platypus/Now, from perspective of the animal, such a sequence can be algorithmically implemented as: “if” I [press the left lever twice] “then” [[press right lever twice] “and” [“do not” press left ... Francis Crick Avenue, Cambridge Biomedical -
full Publications
https://www2.mrc-lmb.cam.ac.uk/groups/sbullock/publications/full_publications/Holt, C.E. and Bullock, S.L. (2009) Subcellular mRNA localization in animal cells and why it matters. ... These two authors contributed equally First and corresponding author. Footer. MRC- Laboratory of Molecular Biology, Francis Crick Avenue, CB2 0QH, -
Complete synaptic-resolution connectome of an insect larval brain -…
https://www2.mrc-lmb.cam.ac.uk/complete-synaptic-resolution-connectome-of-an-insect-larval-brain/10 Mar 2023: This work was spearheaded by the groups of Marta Zlatic and Albert Cardona in the LMB’s Neurobiology Division, as well as members of their groups in the University of ... The techniques and computational tools used in this approach can be further -
Centre for Chemical and Synthetic Biology - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/research/protein-and-nucleic-acid-chemistry/centre-for-chemical-and-synthetic-biology/21 Jul 2023: MRC Laboratory of Molecular Biology,. Francis Crick Avenue,. Cambridge Biomedical Campus,. ... Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0QH, UK.
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