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  2. CURRICULUM VITAE

    https://www2.mrc-lmb.cam.ac.uk/groups/bienz/wp-content/uploads/sites/23/BienzCV_March2024.pdf
    11 Apr 2024: co-corresponding authors. 116. van Tienen LM, Mieszczanek J, Fiedler M, Rutherford TJ & Bienz M (2017) Constitutive. ... 1 equal contribution. 129. Mieszczanek J, Strutt H, Rutherford TJ, Strutt D, Bienz M & Gammons MV (2022).
  3. mc4604.qxd

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/current%20opinion%20micro%202001.pdf
    12 Nov 2001: of special interest•• of outstanding interest. 1. Mitchison TJ: Compare and contrast actin filaments andmicrotubules. ... Annu Rev Cell Dev Biol 1999, 15:63-80. 8. Desai A, Mitchison TJ: Microtubule polymerization dynamics.
  4. FtsK in motion reveals its mechanism for double-stranded DNA…

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/FtsK_Jean_2020_PNAS.pdf
    8 Jun 2020: FtsK in motion reveals its mechanism fordouble-stranded DNA translocationNicolas L. Jeana, Trevor J. Rutherforda, and Jan Löwea,1. aStructural Studies Division, Medical Research Council Laboratory of Molecular Biology, Cambridge CB2 0QH,
  5. 14821680963433 1..18

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/e21600-download.pdf
    19 Dec 2016: For correspondence: jyl@mrc-. lmb.cam.ac.uk. Competing interests: The. authors declare that no. competing interests exist. Funding: See page 15. Received: 17 September 2016. Accepted: 14 November 2016. Published: 17 November 2016. Reviewing editor:
  6. pnas201014665 19609..19610

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/PNAS-2010-Nogales-19609-10.pdf
    11 Nov 2010: Int J Biochem Cell Biol 41:323–329. 7. Koshland DE, Mitchison TJ, Kirschner MW (1988) Pole-wards chromosome movement driven by microtubuledepolymerization in vitro.
  7. doi:10.1016/j.jbbm.2005.12.008

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/rfcloning2006%20published.pdf
    19 Apr 2006: 1997;25:4165–6. [7] Gibson TJ. PhD thesis. Cambridge, UK. 1984. [8] Miroux B, Walker JE.
  8. Dynamin architecture—from monomer to polymer

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/dynaminreviewCOSBILow2010.pdf
    21 Oct 2010: 15. Chappie JS, Acharya S, Liu YW, Leonard M, Pucadyil TJ, Schmid SL:An intramolecular signaling element that modulates dynaminfunction in vitro and in vivo. ... 29. Pucadyil TJ, Schmid SL: Real-time visualization of dynamin-catalyzed membrane fission
  9. doi:10.1016/j.biocel.2008.08.010

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/cytomotive2008Lowe.pdf
    17 Sep 2008: Mol Microbiol2004;52:385–98. ggert US, Mitchison TJ, Field CM. Animal cytokinesis: from parts list to mechanisms.Annu Rev Biochem 2006;75:543–66. ... microtubuleassembly. Proc Natl Acad Sci U S A 2008;105:5378–83. omberg L, Mitchison TJ.
  10. Cryo‐EM structure of the full‐length Lon protease from Thermus…

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/Lon%20Coscia%202021%20FEBS.pdf
    14 Nov 2021: Curr Res Struct. Biol 1, 13–20.17 Jean NL, Rutherford TJ and Lowe J (2020) FtsK in.
  11. early in DNA damage response and regulateRAP80 localization. Many ...

    https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/MartensSytPap07.pdf
    16 Oct 2009: syt. st JJ =. Using the above values for syt. sJ and tJ , we obtain 4.0= , meaning.
  12. 15591370691369 1..30

    https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/elife_2019.pdf
    29 May 2019: For correspondence:. rhegde@mrc-lmb.cam.ac.uk. Competing interest: See. page 28. Funding: See page 28. Received: 11 March 2019. Accepted: 15 May 2019. Published: 16 May 2019. Reviewing editor: Maya. Schuldiner, Weizmann Institute,. Israel. Copyright
  13. doi:10.1016/j.coph.2005.03.002

    https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/15963759.pdf
    12 Nov 2006: 33. Broderick DK, Di C, Parrett TJ, Samuels YR, Cummins JM,McLendon RE, Fults DW, Velculescu VE, Bigner DD, Yan H:Mutations of PIK3CA in anaplastic oligodendrogliomas, high-grade astrocytomas, and
  14. Dynamic Filaments of the Bacterial Cytoskeleton

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/annrev2006.pdf
    19 Apr 2006: ANRV277-BI75-21 ARI 24 February 2006 2:50. RE V. I E W. S. IN. A D V A. NC. E. Dynamic Filaments of theBacterial CytoskeletonKatharine A. Michie and Jan LöweMedical Research Council Laboratory of Molecular Biology, Cambridge CB2 2QH,UK; email:
  15. pnas201206839 17424..17429

    https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/23045692.pdf
    21 Nov 2012: midbody and function in cytokinesis. EMBO J 26(19):4215–4227.6. Lindås AC, Karlsson EA, Lindgren MT, Ettema TJ, Bernander R (2008) A unique cell.
  16. A Polymerization-Associated Structural Switch in FtsZ That Enables…

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/mBio-2017-Wagstaff-.pdf
    3 May 2017: A Polymerization-Associated StructuralSwitch in FtsZ That Enables Treadmillingof Model Filaments. James M. Wagstaff,a Matthew Tsim,a María A. Oliva,b Alba García-Sanchez,b. Danguole Kureisaite-Ciziene,a José Manuel Andreu,b Jan Löwea. MRC
  17. Evolving nature of the AP2 a-appendage hubduring clathrin-coated…

    https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/AP2Hub_EMBO2004/AP2Praefcke2004.pdf
    23 Nov 2004: Evolving nature of the AP2 a-appendage hubduring clathrin-coated vesicle endocytosis. Gerrit JK Praefcke1,2, Marijn GJ Ford1,Eva M Schmid, Lene E Olesen,Jennifer L Gallop, Sew-Yeu Peak-Chew,Yvonne Vallis, M Madan Babu,Ian G Mills3 and Harvey T
  18. Features critical for membrane binding revealed by DivIVA crystal…

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/emboj201099a.pdf
    20 May 2010: The EMBO Journal, (2010). doi:10.1038/emboj.2010.99
  19. pnas201313978 4601..4610

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/pnas2013duman.pdf
    23 Dec 2013: Structural and genetic analyses reveal the proteinSepF as a new membrane anchor for the Z ringRamona Dumana,1, Shu Ishikawab,1, Ilkay Celikc,1, Henrik Strahlc, Naotake Ogasawarab, Paulina Troca, Jan Löwea,2,and Leendert W. Hamoenc,d,2. aMedical
  20. doi:10.1016/j.ceb.2004.06.009

    https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/MillsMcMahonAp2Review.pdf
    23 Nov 2004: COP and clathrin-coated vesicle budding: different pathways,common approachesHarvey T McMahon1 and Ian G Mills2. Vesicle and tubule transport containers move proteins and. lipids from one membrane system to another. Newly forming. transport
  21. Recognition and Degradation of Mislocalized Proteins in Health and…

    https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/CSHL_Persp_2019.pdf
    8 Mar 2019: REFERENCES. Arnold A, Horst SA, Gardella TJ, Baba H, Levine MA, Kro-nenberg HM.
  22. CAN-11-2008 3642..3651

    https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/79_Basseville_A_CanRes_2012.pdf
    24 Sep 2015: Cell 2003;115:727–38. 26. Corcoran LJ, Mitchison TJ, Liu Q. A novel action of histone deacetylaseinhibitors in a protein aggresome disease model.
  23. CELL AND MOLECULAR PHYSIOLOGY Intracellular Ca2+ release via the ...

    https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/44_Ong_HL_Pflug_Arch_2007.pdf
    15 Feb 2007: Biochem J289 (Pt 1):71–79. 36. Zhang SL, Yu Y, Roos J, Kozak JA, Deerinck TJ, Ellisman MH,Stauderman KA, Cahalan MD (2005) STIM1 is a Ca2+ sensor thatactivates CRAC
  24. 3747_0_supp_7_1052456676

    https://www2.mrc-lmb.cam.ac.uk/groups/wschafer/christian.pdf
    9 May 2003: Cameleon imaging of calcium transients in cultured mechanosensory neurons in Caenorhabditis elegans. Christian Frøkjær-Jensen Speciale. February 2003 Niels Bohr Institute. University of Copenhagen. 2. Table of contents Abstract. 3 Credit. 4
  25. Biallelic Variants in ASNA1, Encoding a Cytosolic Targeting Factor of …

    https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/CircGen_2019.pdf
    1 Dec 2019: Circ Genom Precis Med. 2019;12:e002507. DOI: 10.1161/CIRCGEN.119.002507 September 2019 397. BACKGROUND: Pediatric cardiomyopathies are a clinically and genetically heterogeneous group of heart muscle disorders associated with high morbidity and
  26. elifesciences.org van den Ent et al. eLife 2014;3:e02634. DOI: ...

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/mrebdouble2014.pdf
    6 Jun 2014: elifesciences.org. van den Ent et al. eLife 2014;3:e02634. DOI: 10.7554/eLife.02634 1 of 22. Bacterial actin MreB forms antiparallel double filamentsFusinita van den Ent1†, Thierry Izoré1†, Tanmay AM Bharat1, Christopher M Johnson2, Jan Löwe1.
  27. Four-stranded mini microtubules formed by Prosthecobacter BtubAB show …

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/PNAS-2017-Deng-E5950-8.pdf
    29 Dec 2017: Four-stranded mini microtubules formed byProsthecobacter BtubAB show dynamic instabilityXian Denga,1, Gero Finka,1, Tanmay A. M. Bharata, Shaoda Hea, Danguole Kureisaite-Cizienea, and Jan Löwea,2. aStructural Studies Division, Medical Research
  28. elifesciences.org Szwedziak et al. eLife 2014;3:e04601. DOI:…

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/FtsZ_Piotr_eLife_2014.pdf
    31 Dec 2014: elifesciences.org. Szwedziak et al. eLife 2014;3:e04601. DOI: 10.7554/eLife.04601 1 of 22. Architecture of the ring formed by the tubulin homologue FtsZ in bacterial cell divisionPiotr Szwedziak†, Qing Wang†, Tanmay A M Bharat, Matthew Tsim, Jan
  29. 15211199233993 1..45

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/MreBHussain2018.pdf
    15 Mar 2018: For correspondence:. egarner@g.harvard.edu. †These authors contributed. equally to this work. Competing interests: The. authors declare that no. competing interests exist. Funding: See page 32. Received: 03 October 2017. Accepted: 21 February
  30. plbi-04-09-03 1532..1548

    https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/SchmidBetaPaper/BetaHub.pdf
    31 Aug 2006: Role of the AP2 b-Appendage Hubin Recruiting Partners for Clathrin-CoatedVesicle AssemblyEva M. Schmid. 1[, Marijn G. J. Ford. 1[, Anne Burtey. 2, Gerrit J. K. Praefcke. 3, Sew-Yeu Peak-Chew. 1, Ian G. Mills. 4,. Alexandre Benmerah2. , Harvey T.
  31. Mediation, Modulation, and Consequences of Membrane-Cytoskeleton…

    https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/DohertyMcMahonAnnRevBiophys08.pdf
    22 May 2008: ANRV343-BB37-04 ARI 24 April 2008 15:9. Mediation, Modulation,and Consequences ofMembrane-CytoskeletonInteractionsGary J. Doherty and Harvey T. McMahonMRC Laboratory of Molecular Biology, Cambridge, CB2 0QH, United Kingdom;email:
  32. elife.elifesciences.org MacKinnon et al. eLife 2014;3:e01483. DOI:…

    https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/83_MacKinnon_AL_eLife_2014.pdf
    9 Sep 2015: elife.elifesciences.org. MacKinnon et al. eLife 2014;3:e01483. DOI: 10.7554/eLife.01483 1 of 23. An allosteric Sec61 inhibitor traps nascent transmembrane helices at the lateral gateAndrew L MacKinnon1†, Ville O Paavilainen1†, Ajay Sharma2,
  33. The Biogenesis of Multipass Membrane Proteins

    https://www2.mrc-lmb.cam.ac.uk/groups/hegde/wp-content/uploads/sites/8/2023/08/CSHL_Persp_2022.pdf
    13 Sep 2022: The Biogenesis of Multipass Membrane Proteins. Luka Smalinskait _e and Ramanujan S. Hegde. MRC Laboratory of Molecular Biology, Cambridge CB2 0QH, United Kingdom. Correspondence: rhegde@mrc-lmb.cam.ac.uk. Multipass membrane proteins contain two or
  34. , 130081, published 7 August 20133 2013 Open Biol. ...

    https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Papers/Open%20Biol.-2013-TakedaCombined.pdf
    25 Sep 2013: 130081, published 7 August 20133 2013 Open Biol. Harvey T. McMahon and David M. GloverTetsuya Takeda, Iain M. Robinson, Matthew M. Savoian, John R. Griffiths, Anthony D. Whetton, the plasma membrane and contractile ring in cytokinesis. F-BAR protein
  35. 16262551036386 1..32

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/cohesin%20folding%202021%20elife-67268-v1.pdf
    14 Jul 2021: For correspondence:. jyl@mrc-lmb.cam.ac.uk (JL);. ashley.nasmyth@bioch.ox.ac.uk. (KAN). †These authors contributed. equally to this work. Competing interests: The. authors declare that no. competing interests exist. Funding: See page 28. Received:
  36. Membrane Protein Insertion at the Endoplasmic Reticulum

    https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/75_Shao_S_Ann_Rev_2011.pdf
    9 Nov 2011: Annu. Rev. Cell Dev. Biol. 2011.27:25-56
  37. The Function, Structure, and Origins of the ER Membrane Protein…

    https://www2.mrc-lmb.cam.ac.uk/groups/hegde/wp-content/uploads/sites/8/2023/08/Annual_Rev_Biochem_2022.pdf
    11 Apr 2022: BI91CH08_Hegde ARjats.cls March 3, 2022 15:43. Annual Review of Biochemistry. The Function, Structure, andOrigins of the ER MembraneProtein ComplexRamanujan S. HegdeMedical Research Council Laboratory of Molecular Biology, Cambridge, United

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