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Science Journals — AAAS
www-vendruscolo.ch.cam.ac.uk/fusco2017s.pdf15 Dec 2017: of lipid molecules labeled with aparamagnetic center (PC) were incorporated intothe bilayers (24, 25). ... E. Deas et al., Antioxid. Redox Signal. 24, 376–391 (2016).22. M. -
Oxetane Grafts Installed Site‐Selectively on Native Disulfides to…
www-vendruscolo.ch.cam.ac.uk/martinez-saez2017acie.pdf15 Dec 2017: Complete conversion was ach-ieved after 24 h at 37 88C, as confirmed by HPLC-MS analysis(Supporting Information, Figures S19 and S20). ... Recently, it hasbeen shown that antibodies against CRM197 neutralizeddiphtheria toxin in HIV infected young -
Delivery of Native Proteins into C. elegans Using a Transduction…
www-vendruscolo.ch.cam.ac.uk/perni2017sr.pdf15 Dec 2017: Similar protocols have been employed successfully for transfecting a variety of mammalian cells, including primary cells, which are notoriously resistant to protein transduction23,24. ... Nature 411, 494–498. (2001). 24. Brummelkamp, T. R., Bernards, R. -
Scaling behaviour and rate-determining steps in filamentous…
www-vendruscolo.ch.cam.ac.uk/meisl2017cs.pdf15 Dec 2017: tion exposes new growth competent bril ends through breakage ofrils.12,15,24,25 We model fragmentation by assuming an equal probabilitytation at each monomer in a bril, given by the -
bi6b01178 1..4
www-vendruscolo.ch.cam.ac.uk/aprile2017b.pdf17 Sep 2017: We determined theapparent dissociation constant of Hsp70 to monomeric αSyn,Kd,M, to be 24 3 μM in the nucleotide-free form and 1.8 0.2μM in the ATP-bound ... 2005) Cell. Mol. Life Sci. 62, 670684.(24) Chen, S. W., Drakulic, S., Deas, E., Ouberai, M., -
Monomeric and fibrillar α-synuclein exert opposite effects on the…
www-vendruscolo.ch.cam.ac.uk/chia2017pnas.pdf17 Sep 2017: Theoretical Analysis. The time evolution of the total fibril mass concentration,M(t), is described by the following integrated rate law (23, 24):. ... surements to microscopic mechanisms of protein aggregation. J Mol Biol 421:160–171.24. -
Amyloid-like Fibrils from an α-Helical Transmembrane Protein
www-vendruscolo.ch.cam.ac.uk/stroobants2017b.pdf17 Sep 2017: 1999) Protein misfolding, evolution anddisease. Trends Biochem. Sci. 24, 329332.(11) Rath, A., and Deber, C. ... Nat. Struct. Biol. 9, 381388.(24) Hartong, D. T., Berson, E. L., and Dryja, T. -
The molecular chaperones DNAJB6 and Hsp70 cooperate to suppress…
www-vendruscolo.ch.cam.ac.uk/aprile2017sr.pdf17 Sep 2017: 100 years of Lewy pathology. Nat Rev Neurol 9, 13–24, doi:10.1038/. ... Nat Rev Mol Cell Biol. 11, 579–592, doi:10.1038/nrm2941 (2010). 24. Tsai, J. & -
Nanobodies raised against monomeric ɑ-synuclein inhibit fibril…
www-vendruscolo.ch.cam.ac.uk/iljina2017bmcb.pdf17 Sep 2017: For large-mers, the differences in the FRET efficiency histograms are clearly observable, espe-cially at times longer than 24 h. ... b Degradation of the 29 hsamples by the 26S proteasome over 24 h (n = 3, SD, P < 0.05), analyzed by sm-FRET. -
MOAG-4 promotes the aggregation of �-synuclein bycompeting with…
www-vendruscolo.ch.cam.ac.uk/yoshimura2017jbc.pdf17 Sep 2017: Trends Cell Biol. 24,506 –514. 3. Knowles, T. P., Vendruscolo, M., and Dobson, C. ... 2013) Replica-averagedmetadynamics. J. Chem. Theory Comput. 9, 5610 –5617. 24. Kohlhoff, K.
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