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30 Sep 2009: Sci.,1999, 24, 329–332. 21 A. A. Pakula and R. T. Sauer, Geneticanalysis of protein stability and function,Annu. ... Mol. Biol., 2004, 336,313–318. 24 Z. Ignatova, Monitoring protein stabilityin vivo, Microb.

27 Jun 2009: isevidence that peptides corresponding to the regionsof residues 20–25, 24–29, 22–27,47,48 and 22–28 withthe F23Y mutation49 are important in modulating theaggregation process. ... 2006). Protein quality inbacterial inclusion bodies. Trends

2 Jun 2009: 2005). Metalloendoprotease cleavagetriggers gelsolin amyloidogenesis. EMBO J. 24,4124–4132. 19. Platt, G. ... Biochem. Biophys. Res. Commun. 304,101–106. 24. Ivanova, M. I., Thompson, M.

27 Jun 2009: 24) (39.1, 68.3), Eisenberg et al. (ref. 25) (29.7, 52.3),Roseman (ref. ... Structure (London)15:1364 –1367. 24. Kyte J, Doolittle RF (1982) A simple method for displaying the hydrophatic character ofa protein.

27 Jun 2009: E. J. Am. Chem. Soc. 2005,127 (24), 8618–8626. 10.1021/ja805258z CCC: $40.75  XXXX American Chemical Society J. ... 24) Chen, R.; Li, L.; Weng, Z. P. Proteins 2003, 52 (1), 80–87.(25) Lensink, M.

30 Sep 2009: EXPERIMENTAL PROCEDURES. Materials. RS was expressed in Escherichia coli BL21 cellsusing a pT7-7 vector as described in ref 24. ... a cysteine residueintroduced by mutagenesis in the vicinity of the NMR-derivedbinding regions (position 24 for Lac and 62

8 Jul 2009: Trends Biochem. Sci. 24, 329–332. 23. Hamada, D., Yanagihara, I. & Tsumoto, K. ... 24. Yeates, T. O. & Padilla, J. E. (2002). Designingsupramolecular protein assemblies.

8 Jul 2009: and 24, respectively (Figure 2D); this latter value is consistent. with estimates for the maximal amplitudes of helical motion of. ... Biophys. Biomol. Struct. 24, 85–116. Crothers, D.M., and Metzger, H. (1972).

8 Jul 2009: ja07. 5208. 0. simultaneously characterized, resulting in high-resolution con-formational ensembles.16–18 In the present work we use NMRrelaxation data (S2 order parameters)19–24 as restraints inmolecular dynamics ... G. Chem. ReV. 2004, 104,

8 Oct 2009: 17. 18. 19. 20. 21. 22. 23. 24. 25. 26. 27.