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Cooperative Assembly of Hsp70 Subdomain Clusters
www-vendruscolo.ch.cam.ac.uk/wright2018b.pdf23 Sep 2018: with respect to the elements of parameter vector p = (α,K̃,ka).The errors in each kinetic data point were taken as 20% of themeasured values. ... Proc. Natl. Acad. Sci. U. S. A. 107, 20072012.(20) Stengel, F., Baldwin, A. -
Systematic mapping of free energy landscapes of a growing filamin…
www-vendruscolo.ch.cam.ac.uk/waudby2018pnas.pdf27 Sep 2018: 4D), respectively, com-parable with typical activation energies for proline isomerization(20–22 kcal mol1) (22). ... CurrOpin Struct Biol 20:33–45. 4. Kaiser CM, Goldman DH, Chodera JD, Tinoco I, Bustamante C (2011) The ribosomemodulates nascent -
Reversible inhibition of the ClpP protease via an N-terminal…
www-vendruscolo.ch.cam.ac.uk/vahidi2018pnas.pdf23 Sep 2018: 3C. With the exception of the N-terminal domain(the first 20 residues) (Fig. ... 11. 12. 0.00.10.20.3. 11. 12. 1H (ppm)13. C (. pp. m). -
Third generation antibody discovery methods: in silico rational design
www-vendruscolo.ch.cam.ac.uk/sormanni2018csr.pdf18 Dec 2018: f C. ambr. idge. on. 12/1. 8/20. 18 7. :55:. 08 A. ... vers. ity o. f C. ambr. idge. on. 12/1. 8/20. 18 7. -
MobiDB 3.0: more annotations for intrinsic disorder, conformational…
www-vendruscolo.ch.cam.ac.uk/piovesan2018nar.pdf22 Apr 2018: Consensus generation is han-dled by MobiDB-lite (51), which uses a stronger majoritythreshold and enforces at least 20 consecutive disorderedresidues to provide highly specific predictions. ... Bioinformatics,doi:10.1093/bioinformatics/btx590. 20. -
Multistep Inhibition of α-Synuclein Aggregation and Toxicity in Vitro …
www-vendruscolo.ch.cam.ac.uk/perni2018acb.pdf23 Sep 2018: μM ThT in 20 mM phosphate buffer (pH 6.5) under quiescent conditions at 37 C. ... 1days and at D5 to 20 1 days, in each case exceeding thelongevity of healthy control animals. -
Submitted 16 March 2018Accepted 8 June 2018Published 4 July ...
www-vendruscolo.ch.cam.ac.uk/papaleo2018pj.pdf23 Sep 2018: simulation. NaCl was added to a concentration of 20 mM to reproduce theexperimental conditions at which chemical shifts and NOEs were determined (Kjaergaard,Teilum & Poulsen, 2010). ... 0.2. 0.4. 0.6. 0.8. 1. 0 10 20 30 40 50. -
Chemical Kinetics for Bridging Molecular Mechanisms and Macroscopic…
www-vendruscolo.ch.cam.ac.uk/michaels2018arpc.pdf22 Apr 2018: Typically, a mature amyloid fibril can extend up to 10 μmin length and has cross-sectional dimensions in the range 2–20 nm (12, 13). ... 0.4. 0.6. 0.8. 1.0. Fibr. il fr. acti. on. 20 4 6 8 10. -
OP-CBIO180177 2944..2950
www-vendruscolo.ch.cam.ac.uk/liberis2018b.pdf23 Sep 2018: individual loop type level (median across loops of the same type 30–45%, median across all loop types <20%). ... self a vector consisting of two concatenated parts:• One-hot encoding of the type of the residue (20 possible. -
Cholesterol catalyses Aβ42 aggregation through a heterogeneous…
www-vendruscolo.ch.cam.ac.uk/habchi2018nc.pdf26 May 2018: entr. atio. n. 1 20.5 3. 1. 10. 5. 2. 0.0. ... a. Secondary pathways. Nor. mal. ized. tim. e. tlag tgrowth. 20-fold accelerationin prm.
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