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Context-Dependent Nature of Destabilizing Mutations on the Stability…
www-jackson.ch.cam.ac.uk/publications/1998/1998_Biochem_Main.pdf17 Sep 2003: O1)Cδ2 11 Leu 103 (Cδ1), Pro 16 (Cγ, CR, Câ), Gln 20. ... S. W., and Holzman, T. F. (1993)Biochemistry 32, 1920-1927. 20. Michnick, S. -
Folding and stability of the ligand-bindingdomain of the…
www-jackson.ch.cam.ac.uk/publications/2002/2002_prot_sci.pdf17 Sep 2003: Fig. 3. Far-UV circular dichroism spectra. Refolded GR-LBD in 20 mMphosphate pH 8.0, 150 mM NaCl, 0.1% Zwittergent 3–12 at 25C (filledcircles) and 95C (open circles) ... C) Far-UV CD ellipticity at 222 nm as a function of denaturant concentration at 3 -
doi:10.1016/S0959-440X(03)00105-2
www-jackson.ch.cam.ac.uk/publications/2003/2003_COSB_main.pdf16 Sep 2003: 60. 70. 80. 10 20 30 40 50 60 70 80 90 100 110. ... 20. Zweifel ME, Barrick D: Studies of the ankyrin repeats of theDrosophila melanogaster Notch receptor. -
Marqusee / Jackson (letter 2)
www-jackson.ch.cam.ac.uk/publications/1999/1999_NSB_Main_Jackson_TFE.pdf16 Sep 2003: Englander, S.W. Nature Struct. Biol. 5, 882–884 (1998).20. Dabora, J.M. & ... Wemmer, D.E. Biopolymers 32, 1695–1702 (1992).20. Luidens, M.K., Figge, J., Breese, K. & -
Journal of Biological Physics 27: 99–117, 2001.© 2001 Kluwer ...
www-jackson.ch.cam.ac.uk/publications/2001/2001_JBP_Main_et_al.pdf16 Sep 2003: The transition state has been characterisedusing three different experimental and computational approaches which are in goodagreement [17, 20]. ... 2. Kinetic investigations. Biochemistry 26 (1989), 691–699. 20. Fulton, K.F., Main, E.R.G., Daggett, V. -
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www-jackson.ch.cam.ac.uk/publications/2002/2002_JACS.pdf15 Sep 2003: For example, the folding of amonomeric form of theλ repressor has been studied by NMRline-shape analysis19 and fluorescence stopped-flow spectros-copy.20 Together with results from protein engineering and ... 98, 7760-7764.(19) Huang, G. S.; Oas, T. G. -
Stimulation of the Weak ATPase Activity of Human Hsp90 by a Client…
www-jackson.ch.cam.ac.uk/publications/2002/2002_jmb.pdf15 Sep 2003: DNA by DNA gyr-ase B.20 All evidence so far suggests that p23 bindsto this state, thereby stabilising the heterocomplexand, for human Hsp90, inhibiting ATP hydrolysis. ... Biol. Chem. 275, 18054-18060. 20. Wigley, D. B., Davies, G. J., Dodson, E. -
Folding Pathway of FKBP12 and Characterisation of the Transition State
www-jackson.ch.cam.ac.uk/publications/1999/1999_JMB2.pdf15 Sep 2003: open triangles).(b) Guandinium chloride-induced unfolding of wild-type FKBP12 in the absence (lled circles) and presenceof 20 mM rapamycin (open circles). ... Comparison with other proteins. There are now at least 20 proteins which havebeen reported to -
Mapping the Interactions Present in the Transition State for…
www-jackson.ch.cam.ac.uk/publications/1999/1999_JMB1.pdf15 Sep 2003: Ala27 1.97 0.17 ÿ6.40 0.20 0.99 0.03 ÿ2.56 0.09 0.38 0.06 0.28 0.03Thr! ... Asp56 3.16 0.20 ÿ3.54 0.10 0.76 0.02 ÿ0.60 0.03 0.08 0.01 0.18 0.01Arg! -
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www-jackson.ch.cam.ac.uk/publications/2003/2003_Biochem.pdf11 Sep 2003: 20 1.11( 0.16 -2.72( 0.32WL59 5.35( 0.05 1.20( 0.08 -2.35( 0.09. ... 20. Kraulis, P. (1991)J. Appl. Crystallogr. 24, 946-950.21. Laitinen, P. J., Brown, K.
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