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LMB 365 - Day 206 - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/lmb-365-day-206/25 Jul 2019: This ensures that supplies are maintained to the cell storage banks and specialist equipment in the EM facility, X-ray sets and NMR and allows the LMB to function 24/7. -
Activation of GCN2 by the ribosomal P-stalk
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/PNAS_2019.pdf7 Mar 2019: Yeast GCN2 forms aconstitutive dimer even in the absence of activation, principallythrough the CTD (24, 25). ... This lack of clarity was further con-founded by a more recent report that, unlike yeast, mouseGCN2 does not form a stable complex that -
Structural Analysis of the Interaction between the BacterialCell…
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/mBio-2018-Kureisaite-Ciziene-e01346-18.full.pdf5 May 2019: 2) corresponds to the main interaction site that was identified by in vivosite-specific photo-cross-linking (24). ... coil. It was previously shown that a region around R75 in FtsQ links to FtsL (24). -
LMB scientists share their Recipe for Primordial Life at the Royal…
https://www2.mrc-lmb.cam.ac.uk/lmb-scientists-share-their-recipe-for-primordial-life-at-the-royal-society/24 Jul 2019: Published on. 24 July, 2019. A team of researchers from John Sutherland’s and Philipp Holliger’s groups in the LMB’s PNAC Division, took their exhibit, “A Recipe for Primordial -
TTC5 mediates autoregulation of tubulin via mRNA degradation
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/Science_2019.pdf19 Nov 2019: another TTC5 function (22–24), because the effects were not rescued by two unrelated point mutants of TTC5 that perturb autoregulation by different mechanisms. ... Mol. Cell 8, 71–84 (2001). doi:10.1016/S1097-2765(01)00277-5 Medline. 24. X. Hu, R. -
LMB 365 - Day 267 - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/lmb-365-day-267/24 Sep 2019: Published on. 24 September, 2019. LMB scientists will be taking C. -
LMB 365 - Day 114 - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/lmb-365-day-114/23 Apr 2019: Published on. 24 April, 2019. Day 114 of #LMB365. Ferris Beuller would never go to the lab on such a spectacular spring day! -
Biallelic Variants in ASNA1, Encoding a Cytosolic Targeting Factor of …
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/CircGen_2019.pdf1 Dec 2019: due to impaired ASNA1-mediated nuclear targeting.24 Though emerin staining showed apparently normal localization of the protein in our patients, it did reveal the characteristic abnormal nuclear morphology previously described ... J Cardiovasc Dev Dis. -
Functionalized graphene sheets on gold grids aid structure…
https://www2.mrc-lmb.cam.ac.uk/functionalized-graphene-sheets-on-gold-grids-aid-structure-determination-by-electron-cryo-microscopy/19 Jun 2019: Naydenova, K., Peet, MJ., Russo, CJ. PNAS 116(24): 11718-11724. -
Articleshttps://doi.org/10.1038/s41594-019-0196-z 1MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/Burmann%202019%20NSMB.pdf4 Mar 2019: Cell 163, 1628–1640 (2015). 24. Bürmann, F. et al. Tuned SMC arms drive chromosomal loading of prokaryotic condensin. ... Curr. Biol. 21, 12–24 (2011). 27. Badrinarayanan, A., Reyes-Lamothe, R., Uphoff, S., Leake, M.
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