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A genome-wide resource for dissecting transport within cells - MRC…
https://www2.mrc-lmb.cam.ac.uk/a-genome-wide-resource-for-dissecting-transport-within-cells/12 Mar 2024: From images of over 8 million cells, Wong was able to identify and validate nearly 200 genes that affect dynein-based transport, including many that were important for only a subset -
Recordings - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/about-lmb/archive/recordings/21 Jul 2023: CD: 200 minutes, MRC LMB. Francis Crick. Francis Crick interviewed by Soraya de Chadarevian and Leslie Orgel, 14 October 1997. ... DVD: 200 minutes, The Biochemical Society. Sequences: Dr Fred Sanger interviewed by Horace Judson. -
Behind the scenes: Stephen Holmes and a surprising career switch to…
https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/share-your-memories/behind-the-scenes-stephen-holmes/15 Dec 2023: Since we’ve moved in, we’ve doubled the amount of high-power server facilities from 200 to 400 kilowatts. -
Activation of the integrated stress response by inhibitors of its…
https://www2.mrc-lmb.cam.ac.uk/activation-of-the-integrated-stress-response-by-inhibitors-of-its-kinases/8 Sep 2023: These findings are important because ISR kinase inhibitors have been used in over 200 pre-clinical studies during the past 10 years, but at the concentrations broadly used, these compounds activate -
CURRICULUM VITAE
https://www2.mrc-lmb.cam.ac.uk/groups/bienz/wp-content/uploads/sites/23/BienzCV_March2024.pdf11 Apr 2024: In "Development and Neurobiology of Drosophila", eds Siddiqui O, Babu P, Hall LM & Hall JC, Plenum Press, New York and London, pp 183-200. -
Substrate-driven assembly of a translocon for multipass membrane…
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/wp-content/uploads/sites/8/2023/08/Nature_2022b.pdf19 Aug 2023: 4c). ΔGapp9.8–0.4–3.7. ΔGapp1. –0.32. –0.33. –3.7. YIPF1(1–200) Sec61β(201–221)N. Flag1 2. YIPF1. ... The 221-residue Flag–YIPF1(1–200)–Sec61β series was generated by Gibson cloning DNA fragments (Twist Biosciences) into a -
The patterned assembly and stepwise Vps4-mediated disassembly of…
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/Hurtig%202023%20sciadv.ade5224.pdf16 Jul 2023: STK strains were supplemented with 200 μM EdU(Thermo Fisher Scientific, C10639) for 10 min. ... Three microliters of resus-pended cells were applied to a freshly glow-discharged QuantifoilAu 200 mesh R2/2 or R2/1 grid. -
Filament structure and subcellular organization of the bacterial…
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/Liu_PNAS_crescentin_2024.pdf28 Apr 2024: M446 (M443)F. G. 200 Å. Nanobody. Nanobody. Nanobody. Nanobody. Fig. 2. ... Scale bar, 100 nm.) The Insets (Scale bar, 200 nm.) in A and D show a close- up view of the area outlined by the dashed rectangle. -
Proteins containing photosynthetic reaction centre domains modulate…
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/Nussbaum_Nat_micro_2024.pdf1 Mar 2024: CdpB2. SepF. SepFCdpB1. 200. Abso. rban. ce (a. u.). Abso. rban. ... For 1 transformation, 200 µl of the prepared cell suspension was used. -
Diverse cytomotive actins and tubulins share a polymerization switch…
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/Wagstaff%202023Sci%20Advances%20cytomotive%20switch%20sciadv.adf3021.pdf16 Jul 2023: The exchanged tubulin wasthen injected onto a Superdex 200 3.2/300 column (GE Health-Care), equilibrated, and eluted in 80 mM K-Pipes, 100 μM Na-GDP, 100 μM MgCl2, ... A total of 2.5 μl was appliedto a gold-on-gold grid (UltrAuFoil R2/2 200 mesh),
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