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News - Cambs 24
https://www2.mrc-lmb.cam.ac.uk/archive/articles/Road_named_after_legendary_scientist.pdf1 Feb 2013: Copyright 2013 Archant Regional Ltd. All rights reserved. News - Cambs 24 http://www.cambs24.co.uk/news/cambridge_road_to_be_na. -
bic079a
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/DonaldsonJ.pdf11 Aug 2008: In cells, the Arf GTP-bind-ing and hydrolysis cycle is regulated by GEFs (guanine-nucleo-tide-exchange factors) and GAPs (GTPase-activating proteins).There are 14 GEFs and 24 GAPs ... EMBO J. 24,2244–2253. 10 Peter, B. J., Kent, H. M., Mills, I. -
Impress
https://www2.mrc-lmb.cam.ac.uk/coot/ephemera/beyond-coloured-lines.pdf28 Sep 2020: Aids). 23 / 50. Screenshots. 24 / 50. Generic Objects. 25 / 50. ... Slide 24. Slide 25. Slide 26. Slide 27. Slide 28. Slide 29. -
Molecular basis for membraneremodelling and organization Deadline for …
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/F-BAR_proteins/Le%20Poster_DEUXNew.pdf29 Sep 2011: 24-28 September 2011. Main Topics:Membrane curvature invesicle fusion. Membrane curvature in endocytosis and vesicle budding. -
Structure of a cholinergic cell membraneNigel Unwina,1 Edited by ...
https://www2.mrc-lmb.cam.ac.uk/groups/nu/pdf/pnasS22.pdf4 Nov 2022: The broken yellow lines identify the well-documented ribbon of δ subunit-linked receptor dimers(14, 15, 18, 24), one of which is labeled in each leaflet to indicate the subunit ... Biophys. J. 92, 3960–3967 (2007). 24. H. W. Chang, E. Bock, Molecular -
IL-17 is a neuromodulator of Caenorhabditis elegans sensory responses
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/Nature_2017.pdf13 Jan 2017: Genetics 159, 133–145 (2001). 24. Gaffen, S. L. Recent advances in the IL-17 cytokine family. ... Optogenetics. L4 animals expressing ChR2 in RMG27 were picked 24 h before the assay and divided into two groups. -
Phosphoinositide-Specific Phospholipase Cδ1 Activity toward Micellar…
https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/9287165.pdf20 Apr 2002: diC7PC (8 mM) no significant activation observed 0.85( 0.06 24.7( 2.9(1.7( 0.2). ... 132) PI-PLCδ1 and at 24-45 C for full-length PI-PLCδ1 (Figure 7A,B). -
Influence of lipid bilayer on the structure of the muscle-type…
https://www2.mrc-lmb.cam.ac.uk/groups/nu/pdf/pnasS24.pdf30 Apr 2024: in cell- derived membrane vesicles (24), or by in situ cryoelectron tomography (25). ... Electron Microscopy Data Bank https://www.ebi.ac.uk/emdb/EMD-18845. Deposited 6 November 2023. 24. N.Unwin, Influence of lipid bilayer on structure of acetylcholine -
The Jour nal o f Cel l Bio logy ...
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/26_Snapp_EL_JCB_2003.pdf16 Oct 2003: The. Jour. nal o. f Cel. l Bio. logy. JCB. Article. The Journal of Cell Biology, Volume 163, Number 2, October 27, 2003 257–269http://www.jcb.org/cgi/doi/10.1083/jcb.200306020 257. Formation of stacked ER cisternae by low affinity protein -
The Journal of Cell Biology © The Rockefeller University ...
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/epsinR/sedequil.pdf16 Jan 2003: Afteran initial scan, the centrifuge was over-speeded at 24,000 rev/min for 6 h, to reduce the time taken to reach equilibrium (Van Holde and Baldwin, 1958),and then ... the speed was reduced and another scan was taken, followed by further scans at -
The Journal of Cell Biology © The Rockefeller University ...
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/sedequil.pdf16 Jan 2003: Afteran initial scan, the centrifuge was over-speeded at 24,000 rev/min for 6 h, to reduce the time taken to reach equilibrium (Van Holde and Baldwin, 1958),and then ... the speed was reduced and another scan was taken, followed by further scans at -
doi:10.1016/j.cub.2004.09.077
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Snx1PeteCullen2004/Snx1PeteCullen2004.pdf23 Nov 2004: Curr. Opin.Cell Biol. 14, 454–462. 24. Seaman, M.N.J., Marcusson, E.G., Cereghino, J.L., and Emr,S.D. -
Microscopy, 2021, 1–6doi:https://doi.org/10.1093/jmicro/dfab023…
https://www2.mrc-lmb.cam.ac.uk/groups/nu/pdf/mic21.pdf26 Jul 2021: acetylcholine receptor clusters in C2C12 myotubes. J. Lipid. Res. 47:2121–2123. 24. -
Sup Fig 1
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/YopJSup.pdf11 Nov 2008: 24 h after transfection cells were serum-starved for 16 h and then stimulated with 20 ng/ml TNF-α. ... 24. 26. 28. 30. 32. 34. 36. 38. 40. 42. inte. -
1 CURRICULUM VITAE Venki Ramakrishnan Nationality U.S. (since 1985)…
https://www2.mrc-lmb.cam.ac.uk/groups/ribo/download/ramakrishnan_cv_4.pdf4 Jan 2024: Nat Struct Mol Biol 24, 866-869. N. R. James, A. Brown, Y. ... 123, 24-34. Gerchman, S.E. and Ramakrishnan, V. (1987). Chromatin higher-order structure studied by neutron scattering and scanning transmission electron microscopy. -
KWRM_A_992668_O
https://www2.mrc-lmb.cam.ac.uk/groups/wschafer/2015-3.pdf20 Oct 2015: Submitted: 11/06/2014. Revised: 11/21/2014. Accepted: 11/24/2014. http://dx.doi.org/10.4161/21624054.2014.992668This is an Open Access article distributed under theterms of the ... Molecular anatomy of a trafficking organelle.Cell 2006; 127:831-46; -
PII: 0304-3991(84)90197-9
https://www2.mrc-lmb.cam.ac.uk/groups/nu/pdf/ultram84.pdf26 Oct 2008: The capacity of the Dewar is sufficient to give a running time of about 24 h under these conditions. -
53091 361..366
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/McMahonE.pdf3 Dec 2004: 24). Thus our experiments point to a pioneering role forepsin in vesicle budding as it provides both a driving force and a linkbetween membrane invagination, clathrin polymerization and AP2complex recruitment. ... beta 2-adaptin appendage domain. EMBO J. -
A Large Particle Associated with the Perimeter of the ...
https://www2.mrc-lmb.cam.ac.uk/groups/nu/pdf/jcb82.pdf5 Jul 2010: Best preserved porecomplexes show evidence of 16- and 24-fold harmonics inaddition to the basic eightfold harmonic (Fig. ... J. CellBiol. 52:338-354. 24. Paine, P. L. , L, C. Moore, and S. -
Structural and Mechanistic Comparison of Prokaryotic and Eukaryotic…
https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/9466937.pdf15 Jan 1998: 139 (E) 394 412 (Ta3) 2.64 (9)4 490 495 (Ta4) 5 6 205 222 (F) 525 534 (Ta5) 2.24 (5)60 536 545 (Ta50) 7 243 263 (G) ... 24%. Despite this relatively weak con-servation both enzymes share a very similar three-dimensional structure (Moser et al., 1997). -
se289900215p
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/strucrev.pdf6 Jul 1999: Adaptors EM, rotary shadow and deep-etch; APcomplexes (13). ;25 (2D). Crystallography; AP2 m2 residues 158 to435 (24). ... 2.7 Phe174, Arg423 (24) YxxØ endocytosis signals. Crystallography; AP2 COOH-terminala-adaptin appendage domain residues701 to 938 -
Organization of spines on the dendritesof Purkinje cellsJohn O’Brien…
https://www2.mrc-lmb.cam.ac.uk/groups/nu/pdf/pnas06.pdf25 Jul 2006: 2004) Nat. Rev. 5, 24 –34.4. Matus, A. (2000) Science 290, 754 –758.5. ... T., Wong, R. O. L. & Lichtman, J. W. (2000) Neuron 27, 219 –225.24. -
Structure and superorganization of acetylcholinereceptor–rapsyn…
https://www2.mrc-lmb.cam.ac.uk/groups/nu/pdf/pnas13.pdf3 Jul 2013: 20%of the receptors showed restricted diffusion in small domains of50 nm, whereas the majority of the receptors were immobile (24).Confocal microscopy of overexpressed rapsyn in nonmuscle. ... The cross-linking of receptors by rapsyn,therefore, seems to -
Tutorial 4: Statistical Theory;Why is the Gaussian Distribution so ...
https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/courses/lmb_statistics_course_2014/tutorials/statistical_theory_why_is_the_gaussian_distribution_so_popular_answers.pdf25 Mar 2014: If X Bin(100, 0.4) then E(X) = 40 and V ar(X) = 24. ... 8. pnorm(35,40,sqrt(24)). Answer: 0.154 (3sf). Statistical Theory; Why is the Gaussian Distribution so popular? -
se060101051p
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/ford01.pdf3 Dec 2004: The COOH-termi-nal domains of these proteins contain clath-rin-binding motifs (3, 24 ), as well as Asp-Pro-Phe (DPF)-like a- and b-adaptin–. ... De Camilli, A. T.Brunger, J. Cell Biol. 149, 537 (2000). 24. -
1202.tif
https://www2.mrc-lmb.cam.ac.uk/groups/nu/pdf/jcb84.pdf16 Jun 2006: Science (Wash. DC). 208:1454-1457. 24. Ross, M. J., M. W. Klymkowsky, D. ... J. Ultrastruct. R e s 24:454-564. 27. Ziogsheim, H.-P., D.-C. Neugehauer, F. -
MergedFile
https://www2.mrc-lmb.cam.ac.uk/groups/nu/pdf/iucrj17.pdf24 May 2017: L., Graf-Meyer, A., Vogel, H. & Stahlberg, H. (2016). Structure, 24,165–170. -
struct1345mmc1
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/FCH02F-BAR_SUP07.pdf2 Jun 2007: After the overspeeding, interference scans were taken at 24 h intervals, and, when. -
Acetylation of MEK2 and I{kappa}B kinase (IKK) activation loop…
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/YopJ.pdf28 Nov 2006: CELL. BIO. LOG. Y. radation of -catenin (24). It is thus possible that YopJ-relatedAvrA may also possess an acetyl transferase activity allowing itto inactivate IKK thereby exerting its effect on ... Gastrointest Liver Physiol 287:G220 –227.24. -
61 Ultramicroscopy 25 (1988) 279-292 North-HoUand, Amsterdam 279…
https://www2.mrc-lmb.cam.ac.uk/groups/nu/pdf/ultram88.pdf1 Apr 2016: to be a pure phase object [21-23]; combination of several images of the same specimen recorded over a range of un-derfocus values [20,24]. ... 24] R.H, Vogel. S.W. Provencher, C.-H. von Bonsdorff, M. Adrian and J. -
INVITED REVIEW Mechanosensory molecules and circuits in C. elegans ...
https://www2.mrc-lmb.cam.ac.uk/groups/wschafer/2015-2.pdf10 Dec 2014: These mayinclude proposed extracellular tethers such as MEC-1 orMEC-9 [24] or alternatively may involve other, as yet uniden-tified sensor proteins. ... Nature 349(6310):588–593. doi:10.1038/349588a0. 24. Du H, Gu G, William CM, Chalfie M (1996) -
TBS may template.qxd
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/EMreview.pdf3 May 2002: In each of thesecases, purified soluble factors and syntheticliposomes are sufficient to reconstitute coatformation [21–24]. ... Proc. Natl. Acad. Sci. U. S. A. 95,11199–11204. 24 Matsuoka, K. -
Dynamin-dependent and dynamin-independentprocesses contribute to the…
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Graham02.pdf29 Apr 2002: an electron-dense core (24).The use of lipophilic FM dyes to follow vesicle cycling has alsosuggested the existence of fast kiss-and-run exocytosis in syn-aptosomes (25) and in ... timedetermined. For control cells, the data are derived from 12 cells and -
ELIFE07975 1..21
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/94_Voorhees_RM_eLife_2015.pdf11 Aug 2015: By contrast, TMDs responsible for targeting aremarkedly more hydrophobic and between 17 to 24 residues long. -
se289900215p
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/research/strucrev.pdf6 Jul 1999: Adaptors EM, rotary shadow and deep-etch; APcomplexes (13). ;25 (2D). Crystallography; AP2 m2 residues 158 to435 (24). ... 2.7 Phe174, Arg423 (24) YxxØ endocytosis signals. Crystallography; AP2 COOH-terminala-adaptin appendage domain residues701 to 938 -
73885 949..955
https://www2.mrc-lmb.cam.ac.uk/groups/nu/pdf/nature03.pdf19 Jun 2003: 4.3 Å 47.9 63.8 64.3 68.4 33.24.3–4.0 Å 56.5 71.8 71.3 77.2 41.6. ... 205, 137–142 (1986). 24. Imoto, K. et al. Location of a d-subunit region determining ion transport through the acetylcholine. -
EMBO Practical Course on the Crystallization of Macromolecular…
https://www2.mrc-lmb.cam.ac.uk/groups/cartera/download/cv/2020_01_Carter_CV.pdf31 Jan 2020: Nat Cell Biol. 18: 1018-24. 11) Schmidt H, Carter AP‡ (2016) Review: Structure and mechanism of the dynein. ... Science. 322: 1691-5. 24) Gennerich A, Carter AP, Reck-Peterson SL, Vale RD‡ (2007) Force-induced bidirectional stepping of cytoplasmic -
Cryo-EM Model-Buildingwith Modern Coot Paul Emsley@ Ben Gurion…
https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/files/coot-2020-nov-slac.pdf10 Nov 2020: Slide 23. Slide 24. Slide 25. Slide 26. Slide 27. Slide 28. -
TBS may template.qxd
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/epsin/EM/mcmahon.pdf3 May 2002: In each of thesecases, purified soluble factors and syntheticliposomes are sufficient to reconstitute coatformation [21–24]. ... Proc. Natl. Acad. Sci. U. S. A. 95,11199–11204. 24 Matsuoka, K. -
Mechanisms of Dense Core Vesicle Recapture following “Kiss andRun” ...
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Insulin_Tsuboi_JBC2004/Insulin_TsuboiJBC2004.pdf6 Dec 2004: Received for publication, July 20, 2004, and in revised form, August 24, 2004Published, JBC Papers in Press, August 25, 2004, DOI 10.1074/jbc.M408179200. ... MIN6 Cell Culture—MIN6 -cells (24) were used between passages19 and 30 and grown in -
se060101051p
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/epsin/EM/ford.pdf3 Dec 2004: The COOH-termi-nal domains of these proteins contain clath-rin-binding motifs (3, 24 ), as well as Asp-Pro-Phe (DPF)-like a- and b-adaptin–. ... De Camilli, A. T.Brunger, J. Cell Biol. 149, 537 (2000). 24. -
bic054a
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/LundmarkBJ2008.pdf11 Aug 2008: with negative curvature, is unaffected [24]. ... Biol. Chem. 264, 21066–21072. 24 Antonny, B., Bigay, J., Casella, J. -
FigS1
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/SchmidBetaPaper/BetaHubSup.pdf7 Sep 2006: AP180(27), Eps15(6). Dynamin1,2,3 (89,30,24), Amph1(24). Eps15R(52), AP180(5), Dynamin1(1). Amph1(15), Eps15R(2). Amph2(40), Epsin1(1). -
Changes in Postural Syntax Characterize Sensory Modulation and…
https://www2.mrc-lmb.cam.ac.uk/groups/wschafer/2015-5.pdf14 Aug 2015: chemoattractant benzaldehyde [24]. ... Worms were transferred to retinal platesat the L4 stage, left at 20C, and assayed either 24 hours later as adults (AQ2026) or in the next. -
M410_8e 231..235
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Dynamin.pdf6 Mar 2001: 24. Vallis, Y., Wigge, P., Marks, B., Evans, P. R. & McMahon, H. -
53091 361..366
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/McMahon01020.pdf3 Dec 2004: 24). Thus our experiments point to a pioneering role forepsin in vesicle budding as it provides both a driving force and a linkbetween membrane invagination, clathrin polymerization and AP2complex recruitment. ... beta 2-adaptin appendage domain. EMBO J. -
Mechanism of ribosome stalling during translation of a poly(A) tail
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/NSMB_2019.pdf25 Nov 2019: The stalled ribosome triggers the ‘no-go’ or ‘nonstop’ pathways of mRNA decay10,13,17,18, nascent protein degra-dation via ribosome-associated quality control12,19–23 and ribosome ... 24,25,30,31). A second mechanism involves detecting the -
early in DNA damage response and regulateRAP80 localization. Many ...
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/MartensSytPap07.pdf16 Oct 2009: Wang, P. R. Andreassen, A. D. D’Andrea, Mol. Cell.Biol. 24, 5850 (2004). ... S4). Because of its Ca2+-independentinteraction with the tSNAREs and/or PtdIns(4,5)P2in the plasma membrane (13, 24), syt1 in the syn-aptic vesicle is closely associated with -
KS_2012_A5_Meeting.indd
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/conferences/2012_A5_Save_the_Date.pdf19 Sep 2011: Late-Breaking Abstract:October 24, 2011. Early Registration:November 21, 2011. Deadlines. late-breaking research • cross-disciplinary collaboration • networking opportunities • peer-reviewed meeting programs. -
httDownloaded from rsif.royalsocietypublishing.org ResearchCite this…
https://www2.mrc-lmb.cam.ac.uk/groups/wschafer/2015-1.pdf4 Feb 2015: Electrophysiological recordings from immobilizedand dissected C. elegans were essentially performed as describedpreviously [24]. ... in muscle indicatesa latency of the order of 80 ms [24].
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