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Functional Depletion of Mahogunin by Cytosolically Exposed Prion…
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/59_Chakrabarti_O_Cell_2009.pdf13 Jun 2009: Some familial PrP mutants generateincreased CtmPrP, a transmembrane isoform associ-ated with disease. ... a direct correlation between the extent of cytosolic PrP exposure. and Mgrn dysfunction. -
Publications
https://www2.mrc-lmb.cam.ac.uk/groups/greger/publications/Commun Biol 4(1): 1056. Watson, J.F., Pinggera, A., Ho, H., Greger, I.H. ... Structure 27(2): 241-252.e3. Buonarati, O.R., Hammes, E.A., Watson, J.F., Greger, I.H., Hell, J.W. -
coot-user-manual.dvi
https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/web/docs/coot-user-manual.pdf28 Sep 2012: 16311.85.2 watson-crick-pair. 16411.85.3 watson-crick-pair-for-residue-range. 164. xix. 11.86 Sequence (Assignment). 16411.86.1 print-sequence-chain. ... Chapter 1: Introduction 2. • a program to do refinement2. • a protein crystallographic suite3. -
https://www2.mrc-lmb.cam.ac.uk/groups/sbullock/wp-json/wp/v2/pages/58
https://www2.mrc-lmb.cam.ac.uk/groups/sbullock/wp-json/wp/v2/pages/58 -
Twinning and other pathologies Andrey Lebedev CCP4 OD-‐structures…
https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/courses/lmb_crystallography_course_2013/lectures/pathologies_and_twinning.pdf11 Jun 2013: 04/06/2013 Crystallography Course LMB 13. a'. a c. c'. Uppenberg et al. ... a. b. Human macrophage receptor CLEC5A for dengue virus Watson, A. -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/9046
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/9046James Watson returned to the LMB to deliver a special talk about Francis Crick, marking the centenary of Francis’ birth.u00a0 Francis and Jim cracked the secret of the DNA structure ... n","protected":false},"excerpt":{"rendered":". James Watson -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/14153
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/14153By simulating the activity of individual synapses on a neuron, seen as deflections in this image for day 100 of #LMB365, Jake Watson in Ingo Gregeru2019s group in Neurobiology can investigate -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/14091
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/14091fluorescent protein which has allowed Jake Watson to visualise them. ... protein which has allowed Jake Watson to visualise them. -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/221
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/221factors. n. He then returned to the LMB in 1970 as a staff scientist – a position he held until his retirement in 2008. ... n. The resulting compensating writhe then facilitates the concerted packing of the parallel stacks into a 2-start helical coil. -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/19717
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/19717a flat honeycomb structure that can inhibit endocytosis of receptors from the cell surface. ... nnnn. A sheet of proteins (pink and blue) forms a honeycomb-like structure over the surface of a cell. -
https://www2.mrc-lmb.cam.ac.uk/groups/greger/wp-json/wp/v2/pages/15
https://www2.mrc-lmb.cam.ac.uk/groups/greger/wp-json/wp/v2/pages/152003/a/lilia href="#pub2002"2002/a/lilia href="#pub2000"2000/a/lilia href="#pub1998"1998/a/li/ulh3 id="pub2024"2024/h3ul class="lmbpubmedpapers"lispan class="pubAuthors"Stockwell, I., Watson, ... 2): 241-252.e3/span/lilispan class="pubAuthors"Buonarati, O -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/22
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/22L. Bragg: A Few Personal Recollections’ by Francis Crick/lili‘Bragg’s Foreword to emThe/em emDouble Helix/em‘ by James Watson/lili‘Reminiscences of Sir Lawrence Bragg’ by Aaron ... The Crick and Watson Story’, ‘Some Milestones in UK -
Image365 - Page 51 of 61 - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/news-events/image365/page/51/These hold milling cutters concentric to the spindle in a very tight grip. ... protein which has allowed Jake Watson to visualise them.
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Image365 - Page 44 of 61 - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/news-events/image365/page/44/Imagine having a meeting here with this eminent group looking down upon you. ... By simulating the activity of individual synapses on a neuron, seen as deflections in this image for day 100 of #LMB365, Jake Watson in Ingo Greger’s group in Neurobiology
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https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/14175
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/14175LMB 365 – Day 96"},"content":{"rendered":". Jim Watson was born on this day in 1928. ... n","protected":false},"excerpt":{"rendered":". Jim Watson was born on this day in 1928. He joined the MRC Unit in Cambridge in 1951, where he met and began working -
Twinning and other pathologies Andrey Lebedev CCP4 OD-‐structures…
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/%22https:/www2.mrc-lmb.cam.ac.uk/download/twinningaandaotherapathologiesa-andreyalebedeva-a/?wpdmdl=18788&11 Jun 2013: 04/06/2013 Crystallography Course LMB 13. a'. a c. c'. Uppenberg et al. ... a. b. Human macrophage receptor CLEC5A for dengue virus Watson, A. -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/8612
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/8612{"id":8612,"date":"2016-03-18T10:46:45","date_gmt":"2016-03-18T10:46:45","guid":{"rendered":"http://www2.mrc-lmb.cam.ac.uk/?p=8612"},"modified":"2024-03-21T17:04:51","modified_gmt":"2024-03-21T17:04:51","slug":"nanostructures-synthetic-genetic-polyme -
LMB In The News - Page 37 of 87 - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/news-events/lmb-in-the-news/page/37/DNA discovery pioneer James Watson pays tribute to colleague Francis Crick. ... Published on. 10 June, 2016. James Watson returned to the LMB to deliver a special talk about Francis Crick, marking the centenary of Francis’ birth.
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https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/20560
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/20560Cryo-EM structures of a principal AMPA receptor complex in open and closed states provide the first insight into how two major auxiliary subunits modulate receptor function. ... AMPA receptors are a set of membrane proteins that mediate fast signal -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/21397
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/21397{"id":21397,"date":"2021-10-15T10:14:15","date_gmt":"2021-10-15T09:14:15","guid":{"rendered":"https://www2.mrc-lmb.cam.ac.uk/?p=21397"},"modified":"2021-10-28T09:57:04","modified_gmt":"2021-10-28T08:57:04","slug":"how-cellular-clocks-within-heart-cel -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/37738
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/37738It is the hallmark of stem cells, in which one daughter cell specialises to perform a specific function in the organism, while the other becomes another stem cell that keeps the -
Clathrin-mediated endocytosis: Adaptor appendage domains.…
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/Adaptors/Appendages.html26 Sep 2011: This work is still ongoing. These pages are written to accompany a review by Mills et al 2004. ... Gamma-COP appendage (COPI coat subunit). 1 binding site on the platform subdomain (taken from Hoffman et al 2003 and Watson et al 2004). -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/153768
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/153768{"id":153768,"date":"2023-10-18T16:34:27","date_gmt":"2023-10-18T15:34:27","guid":{"rendered":"https://www2.mrc-lmb.cam.ac.uk/?p=153768"},"modified":"2023-10-18T16:35:03","modified_gmt":"2023-10-18T15:35:03","slug":"new-mechanism-found-that-maintains -
A new 2D protein material for studying receptor endocytosis - MRC…
https://www2.mrc-lmb.cam.ac.uk/a-new-2d-protein-material-for-studying-receptor-endocytosis/6 Jan 2021: Joseph Watson, in Emmanuel’s group, reasoned that such a material could have powerful effects on cells. ... Ben-Sasson, AJ., Watson, JL., Sheffler, W., Johnson, MC., Bittleston, A., Somasundaram, L., Decarreau, J., Jiao, F., Chen, J., Mela, I., Drabek,
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Nanostructures from synthetic genetic polymers - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/nanostructures-synthetic-genetic-polymers/18 Mar 2016: specifically from a series of ‘synthetic genetic polymers’, also known as xeno nucleic acids (XNAs). ... Although distinct from DNA and RNA, the XNAs still carry the bases A, T, C and G, so the standard Watson-Crick base pairing rules still operate
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DNA discovery pioneer James Watson pays tribute to colleague Francis…
https://www2.mrc-lmb.cam.ac.uk/dna-discovery-pioneer-james-watson-pays-tribute-colleague-francis-crick/10 Jun 2016: Search this website. DNA discovery pioneer James Watson pays tribute to colleague Francis Crick. ... Published on. 10 June, 2016. James Watson returned to the LMB to deliver a special talk about Francis Crick, marking the centenary of Francis’ birth.
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https://www2.mrc-lmb.cam.ac.uk/groups/shahbazi/wp-json/wp/v2/pages/15
https://www2.mrc-lmb.cam.ac.uk/groups/shahbazi/wp-json/wp/v2/pages/15content":{"rendered":"h3 2024/h3ul class="lmbpubmedpapers"lispan class="pubAuthors"Sato, N., et al./span span class="pubDate"(2024 )/spanbr /a href="http://www.ncbi.nlm.nih.gov/pubmed/38579720" ... ulh3 2023/h3ul class="lmbpubmedpapers"lispan -
https://www2.mrc-lmb.cam.ac.uk/groups/sbullock/wp-json/wp/v2/pages/29
https://www2.mrc-lmb.cam.ac.uk/groups/sbullock/wp-json/wp/v2/pages/29doi: 10.1038/s41594-024-01212-x/span. a href="https://pubmed.ncbi.nlm.nih.gov/38297086/"Pubmed/a/pnpMadan V, Albacete Albacete L, Jin L, Scaturro P, Watson JL, Muschalik ... MAPs, and microtubule ends on directional movement of a localising mRNA./strong -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/16108
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/16108Molecular Biology (LMB) and AstraZeneca to support a range of pre-clinical research projects. ... Stangherlin, A., Watson, J.L., Wong, D.C.S., Barbiero, S., Zeng, A., Seinkmane, E., Peak Chew, S., Beale, A.D., Hayter, E.A., Guna, A., Inglis, A.J., Putker, -
All publications
https://www2.mrc-lmb.cam.ac.uk/ccsb/publications/all-publications-2/J. F. Zürcher, A. A. Kleefeldt, L. F. H. Funke, J. ... J. L. Watson, S. Aich, B. Oller-Salvia, A. A. Drakek, S. -
Coot Scripting Interface: c-interface.h File Reference
https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/docs/html/c-interface_8h.html24 Aug 2021: if this is not a standard group, then turn the atoms to HETATMs. ... screendump_image (const char filename). dump the current screen image to a file. -
Chin
https://www2.mrc-lmb.cam.ac.uk/ccsb/category/publications/feed/3 Apr 2024: Biol/em/emstrong 2021/strong 220 (2): e202009063./abr / J. L. Watson, S. Aich, B. ... 284-285/a,a href="http://cen.acs.org/magazine/89/8907.html" target="_blank" rel="noopener noreferrer"emChem. -
https://www2.mrc-lmb.cam.ac.uk/groups/greger/wp-json/wp/v2/pages/19
https://www2.mrc-lmb.cam.ac.uk/groups/greger/wp-json/wp/v2/pages/19item fg-type-image fg-idle"figure class="fg-item-inner"a href="https://www2.mrc-lmb.cam.ac.uk/groups/greger/wp-content/uploads/sites/32/398_jake-watson.jpg" ... data-caption-title="Jake Watson" data-attachment-id="102" data-type="image" -
https://www2.mrc-lmb.cam.ac.uk/ccsb/wp-json/wp/v2/pages/312
https://www2.mrc-lmb.cam.ac.uk/ccsb/wp-json/wp/v2/pages/312619: 555-562./abr /nJ. F. Zuu0308rcher, A. A. Kleefeldt, L. F. H. ... Biol/em/emstrong 2021/strong 220 (2): e202009063./abr /nJ. L. Watson, S. Aich, B. -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/13500
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/13500Day 362 of #LMB365 shows the LMB Executive Committee after a recent meeting. ... Protein samples frozen on grids in amorphous ice are placed inside a nanocap. -
Jim Watson Outside The Eagle - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/wp-json/oembed/1.0/embed?url=https%3A%2F%2Fwww2.mrc-lmb.cam.ac.uk%2Fphoto-archive%2Fjim-watson-outside-the-eagle%2F&format=xmlcam.ac.uk/photo-archive/jim-watson-outside-the-eagle/">Jim Watson Outside The Eagle</a></blockquote><iframe sandbox="allow-scripts" security="restricted" ... photo-archive/jim-watson-outside-the-eagle/embed/#?secret=qV7y5ebwDe" width="600" height="338" -
Reproduction of Watson & Crick DNA Model - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/wp-json/oembed/1.0/embed?url=https%3A%2F%2Fwww2.mrc-lmb.cam.ac.uk%2Fphoto-archive%2Freproduction-of-watson-crick-dna-model%2F&format=xmlcam.ac.uk/photo-archive/reproduction-of-watson-crick-dna-model/">Reproduction of Watson & Crick DNA Model</a></blockquote><iframe sandbox="allow-scripts" security="restricted" ... ac.uk/photo-archive/reproduction-of-watson-crick-dna-model/embed/#?secret=Z -
Pymol guide
https://www2.mrc-lmb.cam.ac.uk/groups/nagai/download/pymolguide.pdf19 Dec 2017: We can see that there are non-Watson-Crick base pairs here, but the cartoon view of the bases doesn’t show the donor and acceptor groups very well. ... To see how the ligand is bound, PyMOL has a really useful tool.
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