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  2. LMB 365 - Day 100 - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/lmb-365-day-100/
    Thumbnail for LMB 365 - Day 100 - MRC Laboratory of Molecular Biology 9 Apr 2019: By simulating the activity of individual synapses on a neuron, seen as deflections in this image for day 100 of #LMB365, Jake Watson in Ingo Greger’s group in Neurobiology can
  3. nature14896 493..505

    https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/95_Brown_A_Nature_2015.pdf
    19 Aug 2015: with its Watson–Crick edge. ... 4b, c). The main chain of Cys127 from the YxCxxxFmotif can form two hydrogen bonds with the Watson–Crick edge ofA1825 to stabilize its flipped orientation, facilitating stacking of the 12and
  4. New method to untangle the contribution of signalling pathways…

    https://www2.mrc-lmb.cam.ac.uk/new-method-to-untangle-the-contribution-of-signalling-pathways-involved-in-asymmetric-cell-division/
    Thumbnail for New method to untangle the contribution of signalling pathways involved in asymmetric cell division - MRC Laboratory of Molecular Biology 28 Sep 2023: In this study, co-led by Joseph Watson and Lara Krüger, the team developed an assay which allows the contribution of each pathway involved in the process to be dissected. ... Watson, JL., Krüger, LK., Ben-Sasson, AJ., Bittleston, A., Shahbazi, M.,
  5. How cellular clocks within heart cells coordinate daily cardiac…

    https://www2.mrc-lmb.cam.ac.uk/how-cellular-clocks-within-heart-cells-coordinate-daily-cardiac-rhythms/
    Thumbnail for How cellular clocks within heart cells coordinate daily cardiac rhythms - MRC Laboratory of Molecular Biology 15 Oct 2021: cells make as great a contribution to daily variation in heart rate as signals from the nervous system. ... Stangherlin, A., Watson, J.L., Wong, D.C.S., Barbiero, S., Zeng, A., Seinkmane, E., Peak Chew, S., Beale, A.D., Hayter, E.A., Guna, A., Inglis, A.J
  6. Tyrosine Residues in Phospholipase C�2 Essential for the…

    https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/11606584.pdf
    20 Apr 2002: The excitation wavelength was 490 nm, and emission wasmonitored at a wavelength of 535 nm. ... Afterseparation by SDS-PAGE, the gel was subjected to analysis using a PhosphorImager.
  7. PII: S1097-2765(03)00356-3

    https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/gripdomain.pdf
    27 Oct 2003: isoleucine makes a shallower contact withof Arf1, corresponding to Tyr 77 in Arl1. ... genes. Proc. Natl. Acad. Sci. USA90, 8952–8956.Analytical UltracentrifugationCollins, B.M., Watson, P.J., and Owen, D.J.
  8. Twinning and other pathologies Andrey Lebedev CCP4 OD-­‐structures…

    https://www2.mrc-lmb.cam.ac.uk/download/twinningaandaotherapathologiesa-andreyalebedeva-a/?wpdmdl=18788&refresh=667acf688ba0d1719324520
    11 Jun 2013: 04/06/2013 Crystallography Course LMB 13. a'. a c. c'. Uppenberg et al. ... a. b. Human macrophage receptor CLEC5A for dengue virus Watson, A.
  9. 9780470015902.a0029223

    https://www2.mrc-lmb.cam.ac.uk/groups/greger/wp-content/uploads/sites/32/eLS-review_Greger.pdf
    1 Mar 2022: AMPA ReceptorsAlexandra Pinggera, MRC Laboratory of Molecular Biology, Cambridge, UKJake F Watson, MRC Laboratory of Molecular Biology, Cambridge, UKIngo H Greger, MRC Laboratory of Molecular Biology, Cambridge, UK. ... Science 287 (5461): 2262–2267.DOI
  10. Supplemental Materials Supp MethodsSupp Fig. 1 Sequence conservation…

    https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/AP2Hub_EMBO2004/AP2Praefcke2004Sup.pdf
    23 Nov 2004: Q F Q N F L P T V V H P G D L Q T Q L A V Q T K R V A A Q V D ... J Biol Chem278, 46772-46781. Miele, A. E., Watson, P. J., Evans, P.
  11. https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/28

    https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/28
    a/linlia href="#walker"John Walker/a/linlia href="#watson"James Watson/a/lin/uln/div/pnh2 id="arndt"Uli Arndt/h2npimg loading="lazy" decoding="async" width="130" height="200" ... Video Tape: 107 minutes, Wellcome Medical Science Video Archive./linliSee
  12. Functional Depletion of Mahogunin by Cytosolically Exposed Prion…

    https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/59_Chakrabarti_O_Cell_2009.pdf
    13 Jun 2009: Some familial PrP mutants generateincreased CtmPrP, a transmembrane isoform associ-ated with disease. ... a direct correlation between the extent of cytosolic PrP exposure. and Mgrn dysfunction.
  13. Publications

    https://www2.mrc-lmb.cam.ac.uk/groups/greger/publications/
    Commun Biol 4(1): 1056. Watson, J.F., Pinggera, A., Ho, H., Greger, I.H. ... Structure 27(2): 241-252.e3. Buonarati, O.R., Hammes, E.A., Watson, J.F., Greger, I.H., Hell, J.W.
  14. coot-user-manual.dvi

    https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/web/docs/coot-user-manual.pdf
    28 Sep 2012: 16311.85.2 watson-crick-pair. 16411.85.3 watson-crick-pair-for-residue-range. 164. xix. 11.86 Sequence (Assignment). 16411.86.1 print-sequence-chain. ... Chapter 1: Introduction 2. • a program to do refinement2. • a protein crystallographic suite3.
  15. https://www2.mrc-lmb.cam.ac.uk/groups/sbullock/wp-json/wp/v2/pages/58

    https://www2.mrc-lmb.cam.ac.uk/groups/sbullock/wp-json/wp/v2/pages/58
  16. Twinning and other pathologies Andrey Lebedev CCP4 OD-­‐structures…

    https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/courses/lmb_crystallography_course_2013/lectures/pathologies_and_twinning.pdf
    11 Jun 2013: 04/06/2013 Crystallography Course LMB 13. a'. a c. c'. Uppenberg et al. ... a. b. Human macrophage receptor CLEC5A for dengue virus Watson, A.
  17. https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/9046

    https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/9046
    James Watson returned to the LMB to deliver a special talk about Francis Crick, marking the centenary of Francis’ birth.u00a0 Francis and Jim cracked the secret of the DNA structure ... n","protected":false},"excerpt":{"rendered":". James Watson
  18. https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/14153

    https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/14153
    By simulating the activity of individual synapses on a neuron, seen as deflections in this image for day 100 of #LMB365, Jake Watson in Ingo Gregeru2019s group in Neurobiology can investigate
  19. https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/14091

    https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/14091
    fluorescent protein which has allowed Jake Watson to visualise them. ... protein which has allowed Jake Watson to visualise them.
  20. https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/221

    https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/221
    factors. n. He then returned to the LMB in 1970 as a staff scientist – a position he held until his retirement in 2008. ... n. The resulting compensating writhe then facilitates the concerted packing of the parallel stacks into a 2-start helical coil.
  21. https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/19717

    https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/19717
    a flat honeycomb structure that can inhibit endocytosis of receptors from the cell surface. ... nnnn. A sheet of proteins (pink and blue) forms a honeycomb-like structure over the surface of a cell.
  22. https://www2.mrc-lmb.cam.ac.uk/groups/greger/wp-json/wp/v2/pages/15

    https://www2.mrc-lmb.cam.ac.uk/groups/greger/wp-json/wp/v2/pages/15
    2003/a/lilia href="#pub2002"2002/a/lilia href="#pub2000"2000/a/lilia href="#pub1998"1998/a/li/ulh3 id="pub2024"2024/h3ul class="lmbpubmedpapers"lispan class="pubAuthors"Stockwell, I., Watson, ... 2): 241-252.e3/span/lilispan class="pubAuthors"Buonarati, O
  23. https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/22

    https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/22
    L. Bragg: A Few Personal Recollections’ by Francis Crick/lili‘Bragg’s Foreword to emThe/em emDouble Helix/em‘ by James Watson/lili‘Reminiscences of Sir Lawrence Bragg’ by Aaron ... The Crick and Watson Story’, ‘Some Milestones in UK
  24. Image365 - Page 51 of 61 - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/news-events/image365/page/51/
    Thumbnail for Image365 - Page 51 of 61 - MRC Laboratory of Molecular Biology These hold milling cutters concentric to the spindle in a very tight grip. ... protein which has allowed Jake Watson to visualise them.
  25. Image365 - Page 44 of 61 - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/news-events/image365/page/44/
    Thumbnail for Image365 - Page 44 of 61 - MRC Laboratory of Molecular Biology Imagine having a meeting here with this eminent group looking down upon you. ... By simulating the activity of individual synapses on a neuron, seen as deflections in this image for day 100 of #LMB365, Jake Watson in Ingo Greger’s group in Neurobiology
  26. https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/14175

    https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/14175
    LMB 365 – Day 96"},"content":{"rendered":". Jim Watson was born on this day in 1928. ... n","protected":false},"excerpt":{"rendered":". Jim Watson was born on this day in 1928. He joined the MRC Unit in Cambridge in 1951, where he met and began working
  27. Twinning and other pathologies Andrey Lebedev CCP4 OD-­‐structures…

    https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/%22https:/www2.mrc-lmb.cam.ac.uk/download/twinningaandaotherapathologiesa-andreyalebedeva-a/?wpdmdl=18788&
    11 Jun 2013: 04/06/2013 Crystallography Course LMB 13. a'. a c. c'. Uppenberg et al. ... a. b. Human macrophage receptor CLEC5A for dengue virus Watson, A.
  28. https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/8612

    https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/8612
    {"id":8612,"date":"2016-03-18T10:46:45","date_gmt":"2016-03-18T10:46:45","guid":{"rendered":"http://www2.mrc-lmb.cam.ac.uk/?p=8612"},"modified":"2024-03-21T17:04:51","modified_gmt":"2024-03-21T17:04:51","slug":"nanostructures-synthetic-genetic-polyme
  29. LMB In The News - Page 37 of 87 - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/news-events/lmb-in-the-news/page/37/
    Thumbnail for LMB In The News - Page 37 of 87 - MRC Laboratory of Molecular Biology DNA discovery pioneer James Watson pays tribute to colleague Francis Crick. ... Published on. 10 June, 2016. James Watson returned to the LMB to deliver a special talk about Francis Crick, marking the centenary of Francis’ birth.
  30. https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/20560

    https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/20560
    Cryo-EM structures of a principal AMPA receptor complex in open and closed states provide the first insight into how two major auxiliary subunits modulate receptor function. ... AMPA receptors are a set of membrane proteins that mediate fast signal
  31. https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/21397

    https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/21397
    {"id":21397,"date":"2021-10-15T10:14:15","date_gmt":"2021-10-15T09:14:15","guid":{"rendered":"https://www2.mrc-lmb.cam.ac.uk/?p=21397"},"modified":"2021-10-28T09:57:04","modified_gmt":"2021-10-28T08:57:04","slug":"how-cellular-clocks-within-heart-cel
  32. https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/37738

    https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/37738
    It is the hallmark of stem cells, in which one daughter cell specialises to perform a specific function in the organism, while the other becomes another stem cell that keeps the
  33. Clathrin-mediated endocytosis: Adaptor appendage domains.…

    https://www2.mrc-lmb.cam.ac.uk/groups/hmm/Adaptors/Appendages.html
    26 Sep 2011: This work is still ongoing. These pages are written to accompany a review by Mills et al 2004. ... Gamma-COP appendage (COPI coat subunit). 1 binding site on the platform subdomain (taken from Hoffman et al 2003 and Watson et al 2004).
  34. https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/153768

    https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/153768
    {"id":153768,"date":"2023-10-18T16:34:27","date_gmt":"2023-10-18T15:34:27","guid":{"rendered":"https://www2.mrc-lmb.cam.ac.uk/?p=153768"},"modified":"2023-10-18T16:35:03","modified_gmt":"2023-10-18T15:35:03","slug":"new-mechanism-found-that-maintains
  35. A new 2D protein material for studying receptor endocytosis - MRC…

    https://www2.mrc-lmb.cam.ac.uk/a-new-2d-protein-material-for-studying-receptor-endocytosis/
    Thumbnail for A new 2D protein material for studying receptor endocytosis - MRC Laboratory of Molecular Biology 6 Jan 2021: Joseph Watson, in Emmanuel’s group, reasoned that such a material could have powerful effects on cells. ... Ben-Sasson, AJ., Watson, JL., Sheffler, W., Johnson, MC., Bittleston, A., Somasundaram, L., Decarreau, J., Jiao, F., Chen, J., Mela, I., Drabek,
  36. Nanostructures from synthetic genetic polymers - MRC Laboratory of…

    https://www2.mrc-lmb.cam.ac.uk/nanostructures-synthetic-genetic-polymers/
    Thumbnail for Nanostructures from synthetic genetic polymers - MRC Laboratory of Molecular Biology 18 Mar 2016: specifically from a series of ‘synthetic genetic polymers’, also known as xeno nucleic acids (XNAs). ... Although distinct from DNA and RNA, the XNAs still carry the bases A, T, C and G, so the standard Watson-Crick base pairing rules still operate
  37. DNA discovery pioneer James Watson pays tribute to colleague Francis…

    https://www2.mrc-lmb.cam.ac.uk/dna-discovery-pioneer-james-watson-pays-tribute-colleague-francis-crick/
    Thumbnail for DNA discovery pioneer James Watson pays tribute to colleague Francis Crick - MRC Laboratory of Molecular Biology 10 Jun 2016: Search this website. DNA discovery pioneer James Watson pays tribute to colleague Francis Crick. ... Published on. 10 June, 2016. James Watson returned to the LMB to deliver a special talk about Francis Crick, marking the centenary of Francis’ birth.
  38. https://www2.mrc-lmb.cam.ac.uk/groups/shahbazi/wp-json/wp/v2/pages/15

    https://www2.mrc-lmb.cam.ac.uk/groups/shahbazi/wp-json/wp/v2/pages/15
    content":{"rendered":"h3 2024/h3ul class="lmbpubmedpapers"lispan class="pubAuthors"Sato, N., et al./span span class="pubDate"(2024 )/spanbr /a href="http://www.ncbi.nlm.nih.gov/pubmed/38579720" ... ulh3 2023/h3ul class="lmbpubmedpapers"lispan
  39. https://www2.mrc-lmb.cam.ac.uk/groups/sbullock/wp-json/wp/v2/pages/29

    https://www2.mrc-lmb.cam.ac.uk/groups/sbullock/wp-json/wp/v2/pages/29
    doi: 10.1038/s41594-024-01212-x/span. a href="https://pubmed.ncbi.nlm.nih.gov/38297086/"Pubmed/a/pnpMadan V, Albacete Albacete L, Jin L, Scaturro P, Watson JL, Muschalik ... MAPs, and microtubule ends on directional movement of a localising mRNA./strong
  40. https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/16108

    https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/16108
    Molecular Biology (LMB) and AstraZeneca to support a range of pre-clinical research projects. ... Stangherlin, A., Watson, J.L., Wong, D.C.S., Barbiero, S., Zeng, A., Seinkmane, E., Peak Chew, S., Beale, A.D., Hayter, E.A., Guna, A., Inglis, A.J., Putker,
  41. All publications

    https://www2.mrc-lmb.cam.ac.uk/ccsb/publications/all-publications-2/
    J. F. Zürcher, A. A. Kleefeldt, L. F. H. Funke, J. ... J. L. Watson, S. Aich, B. Oller-Salvia, A. A. Drakek, S.
  42. Coot Scripting Interface: c-interface.h File Reference

    https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/docs/html/c-interface_8h.html
    24 Aug 2021: if this is not a standard group, then turn the atoms to HETATMs. ... screendump_image (const char filename). dump the current screen image to a file.
  43. Chin

    https://www2.mrc-lmb.cam.ac.uk/ccsb/category/publications/feed/
    3 Apr 2024: Biol/em/emstrong 2021/strong 220 (2): e202009063./abr / J. L. Watson, S. Aich, B. ... 284-285/a,a href="http://cen.acs.org/magazine/89/8907.html" target="_blank" rel="noopener noreferrer"emChem.
  44. https://www2.mrc-lmb.cam.ac.uk/groups/greger/wp-json/wp/v2/pages/19

    https://www2.mrc-lmb.cam.ac.uk/groups/greger/wp-json/wp/v2/pages/19
    item fg-type-image fg-idle"figure class="fg-item-inner"a href="https://www2.mrc-lmb.cam.ac.uk/groups/greger/wp-content/uploads/sites/32/398_jake-watson.jpg" ... data-caption-title="Jake Watson" data-attachment-id="102" data-type="image"
  45. https://www2.mrc-lmb.cam.ac.uk/ccsb/wp-json/wp/v2/pages/312

    https://www2.mrc-lmb.cam.ac.uk/ccsb/wp-json/wp/v2/pages/312
    619: 555-562./abr /nJ. F. Zuu0308rcher, A. A. Kleefeldt, L. F. H. ... Biol/em/emstrong 2021/strong 220 (2): e202009063./abr /nJ. L. Watson, S. Aich, B.
  46. https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/13500

    https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/13500
    Day 362 of #LMB365 shows the LMB Executive Committee after a recent meeting. ... Protein samples frozen on grids in amorphous ice are placed inside a nanocap.
  47. Jim Watson Outside The Eagle - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/wp-json/oembed/1.0/embed?url=https%3A%2F%2Fwww2.mrc-lmb.cam.ac.uk%2Fphoto-archive%2Fjim-watson-outside-the-eagle%2F&format=xml
    cam.ac.uk/photo-archive/jim-watson-outside-the-eagle/">Jim Watson Outside The Eagle</a></blockquote><iframe sandbox="allow-scripts" security="restricted" ... photo-archive/jim-watson-outside-the-eagle/embed/#?secret=qV7y5ebwDe" width="600" height="338"
  48. Reproduction of Watson & Crick DNA Model - MRC Laboratory of…

    https://www2.mrc-lmb.cam.ac.uk/wp-json/oembed/1.0/embed?url=https%3A%2F%2Fwww2.mrc-lmb.cam.ac.uk%2Fphoto-archive%2Freproduction-of-watson-crick-dna-model%2F&format=xml
    cam.ac.uk/photo-archive/reproduction-of-watson-crick-dna-model/">Reproduction of Watson & Crick DNA Model</a></blockquote><iframe sandbox="allow-scripts" security="restricted" ... ac.uk/photo-archive/reproduction-of-watson-crick-dna-model/embed/#?secret=Z
  49. Pymol guide

    https://www2.mrc-lmb.cam.ac.uk/groups/nagai/download/pymolguide.pdf
    19 Dec 2017: We can see that there are non-Watson-Crick base pairs here, but the cartoon view of the bases doesn’t show the donor and acceptor groups very well. ... To see how the ligand is bound, PyMOL has a really useful tool.

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