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  2. LMB 365 - Day 60 - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/wp-json/oembed/1.0/embed?url=https%3A%2F%2Fwww2.mrc-lmb.cam.ac.uk%2Flmb-365-day-60%2F&format=xml
    1.0 MRC Laboratory of Molecular Biology https://www2.mrc-lmb.cam.ac.uk rich 600 338 <blockquote class="wp-embedded-content" data-secret="kP3V90kGLA"><a ... handful of pseudocoloured hippocampal neurons (brain cells) that have been specifically targeted
  3. LMB 365 - Day 100 - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/wp-json/oembed/1.0/embed?url=https%3A%2F%2Fwww2.mrc-lmb.cam.ac.uk%2Flmb-365-day-100%2F&format=xml
    1.0 MRC Laboratory of Molecular Biology https://www2.mrc-lmb.cam.ac.uk rich 600 338 <blockquote class="wp-embedded-content" data-secret="rYWpG0kesw"><a ... By simulating the activity of individual synapses on a neuron, seen as deflections in this image
  4. LMB 365 - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/news-and-events/lmb-365/
    Thumbnail for LMB 365 - MRC Laboratory of Molecular Biology 21 Jul 2023: Day 362 of #LMB365 shows the LMB Executive Committee after a recent meeting. ... This was the LMB’s second Nobel for 1962, Francis Crick and James Watson had already been awarded the Physiology and Medicine Prize for their work on the structure of DNA.
  5. 1962 - Francis Crick & James Watson - MRC Laboratory of Molecular …

    https://www2.mrc-lmb.cam.ac.uk/wp-json/oembed/1.0/embed?url=https%3A%2F%2Fwww2.mrc-lmb.cam.ac.uk%2Fachievements%2Flmb-nobel-prizes%2F1962-francis-crick-james-watson%2F&format=xml
    cam.ac.uk/achievements/lmb-nobel-prizes/1962-francis-crick-james-watson/">1962 – Francis Crick & James Watson</a></blockquote><iframe sandbox="allow-scripts" security="restricted" ... ac.uk/achievements/lmb-nobel-prizes/1962-francis-crick-james-watson/e
  6. Moments of Genius: Nobel laureate Venki Ramakrishnan describes how…

    https://www2.mrc-lmb.cam.ac.uk/wp-json/oembed/1.0/embed?url=https%3A%2F%2Fwww2.mrc-lmb.cam.ac.uk%2Fmoments-of-genius-nobel-laureate-venki-ramakrishnan-describes-how-james-watson-discovered-dna-base-pairing%2F&format=xml
    base pairing</a></blockquote><iframe sandbox="allow-scripts" security="restricted" ... 182 100 “Nobel laureate Venki Ramakarishnan describes how James Watson discovered DNA base pairing which showed how the DNA double helix could carry.
  7. The Coot User Manual

    https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/web/docs/coot.html
    1 Mar 2021: The Coot User Manual
  8. © 2005 Nature Publishing Group Endophilin and CtBP/BARS are ...

    https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/GallopEndopohilinNature2005.pdf
    4 Jan 2006: Nature 401, 133–-141 (1999). 2. Modregger, J., Schmidt, A. A., Ritter, B., Huttner, W. ... M., Watson, M. D. & Slabas, A. R.Isolation and characterisation of a maize cDNA that complements a 1-acylsn-glycerol-3-phosphate acyltransferase mutant of
  9. Coot Scripting Interface: c-interface.h Source File

    https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/docs/html/c-interface_8h_source.html
    24 Aug 2021: 398 / return a list or python false /. 399 PyObject remarks_py(int imol);. ... 629 does not have the _raw suffix and returns a scheme or python.
  10. INVITED REVIEW Mechanosensory molecules and circuits in C. elegans ...

    https://www2.mrc-lmb.cam.ac.uk/groups/wschafer/2015-2.pdf
    10 Dec 2014: providing decisive evidence that TRP-4 is a pore-forming ionchannel subunit [39]. ... elegans. Neuron 70(2):299–309. doi:10.1016/j.neuron.2011.02.046. 17. Chatzigeorgiou M, Yoo S, Watson JD, Lee WH, Spencer WC, KindtKS, Hwang SW, Miller DM 3rd,
  11. https://www2.mrc-lmb.cam.ac.uk/groups/oneill/wp-json/wp/v2/pages/9

    https://www2.mrc-lmb.cam.ac.uk/groups/oneill/wp-json/wp/v2/pages/9
  12. Proteins containing photosynthetic reaction centre domains modulate…

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/Nussbaum_Nat_micro_2024.pdf
    1 Mar 2024: expressing CdpB2–mNeonGreen from a plasmid under the control of its native promotor. ... Few PRC proteins are associated with other domains such as a zinc ribbon.
  13. Models - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/keywords/models/feed/
    19 Jun 2024: reproduction-of-watson-crick-dna-model/"Reproduction of Watson & Crick DNA Model/a appeared first on a href="https://www2.mrc-lmb.cam.ac.uk"MRC Laboratory of Molecular ... p pThe post a
  14. Jason William Chin Page 1 of 18 MRC Laboratory ...

    https://www2.mrc-lmb.cam.ac.uk/ccsb/wp-content/uploads/2024/01/Chin-cv-26012024.pdf
    29 Jan 2024: assembly. J. F. Zürcher, A. A. Kleefeldt, L. F. H. Funke, J. ... J. L. Watson, S. Aich, B. Oller-Salvia, A. A. Drakek, S.
  15. Herbert ‘Freddie’ Gutfreund - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/alumni/herbert-freddie-gutfreund/
    Thumbnail for Herbert ‘Freddie’ Gutfreund - MRC Laboratory of Molecular Biology 18 Nov 2021: Crick, James Watson and Hugh Huxley. ... Memories of a Senior Scientist: I was lucky, I was there at the right time.
  16. Books - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/about-lmb/archive/books/
    Thumbnail for Books - MRC Laboratory of Molecular Biology 21 Jul 2023: L. Bragg: A Few Personal Recollections’ by Francis Crick. ‘Bragg’s Foreword to The Double Helix‘ by James Watson. ... Minds that live for science’ James Watson. ‘Ruthless research in a cupboard’ Francis Crick.
  17. New mechanism found that maintains intracellular water balance - MRC…

    https://www2.mrc-lmb.cam.ac.uk/new-mechanism-found-that-maintains-intracellular-water-balance/
    Thumbnail for New mechanism found that maintains intracellular water balance - MRC Laboratory of Molecular Biology 18 Oct 2023: Joseph Watson led the imaging studies and yeast experiments, Estere Seinkmane led proteomic and phosphoproteomic analyses and Christine Styles led the cell viability and cell adaptation experiments. ... Further references. Watson, JL., Seinkmane, E.,
  18. Blue Sky Collaboration - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/research/blue-sky-collaboration/
    Thumbnail for Blue Sky Collaboration - MRC Laboratory of Molecular Biology 31 May 2024: Arka Chakraborty is carrying on structural work on a related complex, ATR/ATRIP. ... Stangherlin, A., Watson, J.L., Wong, D.C.S., Barbiero, S., Zeng, A., Seinkmane, E., Peak Chew, S., Beale, A.D., Hayter, E.A., Guna, A., Inglis, A.J., Putker, M.,
  19. doi:10.1016/j.neuron.2005.05.004

    https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Jockusch_Neuron2005.pdf
    17 Jun 2005: B) Examples of capacitancemresponses elicited by a depolarization lasting 100 ms (deliveredDat arrow). ... Neuron 17, 1241–1249. Miele, A.E., Watson, P.J., Evans, P.R., Traub, L.M., and Owen, D.J.(2004).
  20. Recordings - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/about-lmb/archive/recordings/
    Thumbnail for Recordings - MRC Laboratory of Molecular Biology 21 Jul 2023: Isaac Asimov introduces James Watson and Francis Crick in the story of the structure of DNA, 8 July 1974. ... Discovering the double helix. James Watson talks about the discovery of the double helix in a lecture at Cold Spring Harbor Laboratory, November
  21. LMB 365 - Day 60 - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/lmb-365-day-60/
    Thumbnail for LMB 365 - Day 60 - MRC Laboratory of Molecular Biology 28 Feb 2019: Published on. 1 March, 2019. This image for day 60 of #LMB365 shows a handful of pseudocoloured hippocampal neurons (brain cells) that have been specifically targeted with DNA expressing a fluorescent ... protein which has allowed Jake Watson to
  22. LMB 365 - Day 100 - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/lmb-365-day-100/
    Thumbnail for LMB 365 - Day 100 - MRC Laboratory of Molecular Biology 9 Apr 2019: By simulating the activity of individual synapses on a neuron, seen as deflections in this image for day 100 of #LMB365, Jake Watson in Ingo Greger’s group in Neurobiology can
  23. nature14896 493..505

    https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/95_Brown_A_Nature_2015.pdf
    19 Aug 2015: with its Watson–Crick edge. ... 4b, c). The main chain of Cys127 from the YxCxxxFmotif can form two hydrogen bonds with the Watson–Crick edge ofA1825 to stabilize its flipped orientation, facilitating stacking of the 12and
  24. New method to untangle the contribution of signalling pathways…

    https://www2.mrc-lmb.cam.ac.uk/new-method-to-untangle-the-contribution-of-signalling-pathways-involved-in-asymmetric-cell-division/
    Thumbnail for New method to untangle the contribution of signalling pathways involved in asymmetric cell division - MRC Laboratory of Molecular Biology 28 Sep 2023: In this study, co-led by Joseph Watson and Lara Krüger, the team developed an assay which allows the contribution of each pathway involved in the process to be dissected. ... Watson, JL., Krüger, LK., Ben-Sasson, AJ., Bittleston, A., Shahbazi, M.,
  25. How cellular clocks within heart cells coordinate daily cardiac…

    https://www2.mrc-lmb.cam.ac.uk/how-cellular-clocks-within-heart-cells-coordinate-daily-cardiac-rhythms/
    Thumbnail for How cellular clocks within heart cells coordinate daily cardiac rhythms - MRC Laboratory of Molecular Biology 15 Oct 2021: cells make as great a contribution to daily variation in heart rate as signals from the nervous system. ... Stangherlin, A., Watson, J.L., Wong, D.C.S., Barbiero, S., Zeng, A., Seinkmane, E., Peak Chew, S., Beale, A.D., Hayter, E.A., Guna, A., Inglis, A.J
  26. Tyrosine Residues in Phospholipase C�2 Essential for the…

    https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/11606584.pdf
    20 Apr 2002: The excitation wavelength was 490 nm, and emission wasmonitored at a wavelength of 535 nm. ... Afterseparation by SDS-PAGE, the gel was subjected to analysis using a PhosphorImager.
  27. PII: S1097-2765(03)00356-3

    https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/gripdomain.pdf
    27 Oct 2003: isoleucine makes a shallower contact withof Arf1, corresponding to Tyr 77 in Arl1. ... genes. Proc. Natl. Acad. Sci. USA90, 8952–8956.Analytical UltracentrifugationCollins, B.M., Watson, P.J., and Owen, D.J.
  28. Twinning and other pathologies Andrey Lebedev CCP4 OD-­‐structures…

    https://www2.mrc-lmb.cam.ac.uk/download/twinningaandaotherapathologiesa-andreyalebedeva-a/?wpdmdl=18788&refresh=667acf688ba0d1719324520
    11 Jun 2013: 04/06/2013 Crystallography Course LMB 13. a'. a c. c'. Uppenberg et al. ... a. b. Human macrophage receptor CLEC5A for dengue virus Watson, A.
  29. 9780470015902.a0029223

    https://www2.mrc-lmb.cam.ac.uk/groups/greger/wp-content/uploads/sites/32/eLS-review_Greger.pdf
    1 Mar 2022: AMPA ReceptorsAlexandra Pinggera, MRC Laboratory of Molecular Biology, Cambridge, UKJake F Watson, MRC Laboratory of Molecular Biology, Cambridge, UKIngo H Greger, MRC Laboratory of Molecular Biology, Cambridge, UK. ... Science 287 (5461): 2262–2267.DOI
  30. Supplemental Materials Supp MethodsSupp Fig. 1 Sequence conservation…

    https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/AP2Hub_EMBO2004/AP2Praefcke2004Sup.pdf
    23 Nov 2004: Q F Q N F L P T V V H P G D L Q T Q L A V Q T K R V A A Q V D ... J Biol Chem278, 46772-46781. Miele, A. E., Watson, P. J., Evans, P.
  31. https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/28

    https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/28
    a/linlia href="#walker"John Walker/a/linlia href="#watson"James Watson/a/lin/uln/div/pnh2 id="arndt"Uli Arndt/h2npimg loading="lazy" decoding="async" width="130" height="200" ... Video Tape: 107 minutes, Wellcome Medical Science Video Archive./linliSee
  32. Functional Depletion of Mahogunin by Cytosolically Exposed Prion…

    https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/59_Chakrabarti_O_Cell_2009.pdf
    13 Jun 2009: Some familial PrP mutants generateincreased CtmPrP, a transmembrane isoform associ-ated with disease. ... a direct correlation between the extent of cytosolic PrP exposure. and Mgrn dysfunction.
  33. Publications

    https://www2.mrc-lmb.cam.ac.uk/groups/greger/publications/
    Commun Biol 4(1): 1056. Watson, J.F., Pinggera, A., Ho, H., Greger, I.H. ... Structure 27(2): 241-252.e3. Buonarati, O.R., Hammes, E.A., Watson, J.F., Greger, I.H., Hell, J.W.
  34. coot-user-manual.dvi

    https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/web/docs/coot-user-manual.pdf
    28 Sep 2012: 16311.85.2 watson-crick-pair. 16411.85.3 watson-crick-pair-for-residue-range. 164. xix. 11.86 Sequence (Assignment). 16411.86.1 print-sequence-chain. ... Chapter 1: Introduction 2. • a program to do refinement2. • a protein crystallographic suite3.
  35. https://www2.mrc-lmb.cam.ac.uk/groups/sbullock/wp-json/wp/v2/pages/58

    https://www2.mrc-lmb.cam.ac.uk/groups/sbullock/wp-json/wp/v2/pages/58
  36. Twinning and other pathologies Andrey Lebedev CCP4 OD-­‐structures…

    https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/courses/lmb_crystallography_course_2013/lectures/pathologies_and_twinning.pdf
    11 Jun 2013: 04/06/2013 Crystallography Course LMB 13. a'. a c. c'. Uppenberg et al. ... a. b. Human macrophage receptor CLEC5A for dengue virus Watson, A.
  37. https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/9046

    https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/9046
    James Watson returned to the LMB to deliver a special talk about Francis Crick, marking the centenary of Francis’ birth.u00a0 Francis and Jim cracked the secret of the DNA structure ... n","protected":false},"excerpt":{"rendered":". James Watson
  38. https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/14153

    https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/14153
    By simulating the activity of individual synapses on a neuron, seen as deflections in this image for day 100 of #LMB365, Jake Watson in Ingo Gregeru2019s group in Neurobiology can investigate
  39. https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/14091

    https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/14091
    fluorescent protein which has allowed Jake Watson to visualise them. ... protein which has allowed Jake Watson to visualise them.
  40. https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/221

    https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/221
    factors. n. He then returned to the LMB in 1970 as a staff scientist – a position he held until his retirement in 2008. ... n. The resulting compensating writhe then facilitates the concerted packing of the parallel stacks into a 2-start helical coil.
  41. https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/19717

    https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/19717
    a flat honeycomb structure that can inhibit endocytosis of receptors from the cell surface. ... nnnn. A sheet of proteins (pink and blue) forms a honeycomb-like structure over the surface of a cell.
  42. https://www2.mrc-lmb.cam.ac.uk/groups/greger/wp-json/wp/v2/pages/15

    https://www2.mrc-lmb.cam.ac.uk/groups/greger/wp-json/wp/v2/pages/15
    2003/a/lilia href="#pub2002"2002/a/lilia href="#pub2000"2000/a/lilia href="#pub1998"1998/a/li/ulh3 id="pub2024"2024/h3ul class="lmbpubmedpapers"lispan class="pubAuthors"Stockwell, I., Watson, ... 2): 241-252.e3/span/lilispan class="pubAuthors"Buonarati, O
  43. https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/22

    https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/22
    L. Bragg: A Few Personal Recollections’ by Francis Crick/lili‘Bragg’s Foreword to emThe/em emDouble Helix/em‘ by James Watson/lili‘Reminiscences of Sir Lawrence Bragg’ by Aaron ... The Crick and Watson Story’, ‘Some Milestones in UK
  44. Image365 - Page 51 of 61 - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/news-events/image365/page/51/
    Thumbnail for Image365 - Page 51 of 61 - MRC Laboratory of Molecular Biology These hold milling cutters concentric to the spindle in a very tight grip. ... protein which has allowed Jake Watson to visualise them.
  45. Image365 - Page 44 of 61 - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/news-events/image365/page/44/
    Thumbnail for Image365 - Page 44 of 61 - MRC Laboratory of Molecular Biology Imagine having a meeting here with this eminent group looking down upon you. ... By simulating the activity of individual synapses on a neuron, seen as deflections in this image for day 100 of #LMB365, Jake Watson in Ingo Greger’s group in Neurobiology
  46. https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/14175

    https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/14175
    LMB 365 – Day 96"},"content":{"rendered":". Jim Watson was born on this day in 1928. ... n","protected":false},"excerpt":{"rendered":". Jim Watson was born on this day in 1928. He joined the MRC Unit in Cambridge in 1951, where he met and began working
  47. Twinning and other pathologies Andrey Lebedev CCP4 OD-­‐structures…

    https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/%22https:/www2.mrc-lmb.cam.ac.uk/download/twinningaandaotherapathologiesa-andreyalebedeva-a/?wpdmdl=18788&
    11 Jun 2013: 04/06/2013 Crystallography Course LMB 13. a'. a c. c'. Uppenberg et al. ... a. b. Human macrophage receptor CLEC5A for dengue virus Watson, A.
  48. https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/8612

    https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/8612
    {"id":8612,"date":"2016-03-18T10:46:45","date_gmt":"2016-03-18T10:46:45","guid":{"rendered":"http://www2.mrc-lmb.cam.ac.uk/?p=8612"},"modified":"2024-03-21T17:04:51","modified_gmt":"2024-03-21T17:04:51","slug":"nanostructures-synthetic-genetic-polyme
  49. LMB In The News - Page 37 of 87 - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/news-events/lmb-in-the-news/page/37/
    Thumbnail for LMB In The News - Page 37 of 87 - MRC Laboratory of Molecular Biology DNA discovery pioneer James Watson pays tribute to colleague Francis Crick. ... Published on. 10 June, 2016. James Watson returned to the LMB to deliver a special talk about Francis Crick, marking the centenary of Francis’ birth.
  50. https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/20560

    https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/20560
    Cryo-EM structures of a principal AMPA receptor complex in open and closed states provide the first insight into how two major auxiliary subunits modulate receptor function. ... AMPA receptors are a set of membrane proteins that mediate fast signal
  51. https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/21397

    https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/21397
    {"id":21397,"date":"2021-10-15T10:14:15","date_gmt":"2021-10-15T09:14:15","guid":{"rendered":"https://www2.mrc-lmb.cam.ac.uk/?p=21397"},"modified":"2021-10-28T09:57:04","modified_gmt":"2021-10-28T08:57:04","slug":"how-cellular-clocks-within-heart-cel

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