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Cryo-EM structures of a principal AMPA receptor complex in open and closed states provide the first insight into how two major auxiliary subunits modulate receptor function. ... AMPA receptors are a set of membrane proteins that mediate fast signal

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It is the hallmark of stem cells, in which one daughter cell specialises to perform a specific function in the organism, while the other becomes another stem cell that keeps the

{"id":153768,"date":"2023-10-18T16:34:27","date_gmt":"2023-10-18T15:34:27","guid":{"rendered":"https://www2.mrc-lmb.cam.ac.uk/?p=153768"},"modified":"2023-10-18T16:35:03","modified_gmt":"2023-10-18T15:35:03","slug":"new-mechanism-found-that-maintains

data-id="https://pubmed.ncbi.nlm.nih.gov/?term=O%27NeillJS&sort=pubdate"here/a. ... For a selection of our most recent, see below:/pnnnnh2 class="wp-block-heading"Most recent articles/h2nnnul class="lmbpubmedpapers"lispan class="pubAuthors"Watson, J.L.,

cam.ac.uk/achievements/lmb-nobel-prizes/1962-francis-crick-james-watson/">1962 – Francis Crick & James Watson</a></blockquote><iframe sandbox="allow-scripts" security="restricted" ... ac.uk/achievements/lmb-nobel-prizes/1962-francis-crick-james-watson/e

content":{"rendered":"h3 2024/h3ul class="lmbpubmedpapers"lispan class="pubAuthors"Sato, N., et al./span span class="pubDate"(2024 )/spanbr /a href="http://www.ncbi.nlm.nih.gov/pubmed/38579720" ... ulh3 2023/h3ul class="lmbpubmedpapers"lispan

doi: 10.1038/s41594-024-01212-x/span. a href="https://pubmed.ncbi.nlm.nih.gov/38297086/"Pubmed/a/pnpMadan V, Albacete Albacete L, Jin L, Scaturro P, Watson JL, Muschalik ... MAPs, and microtubule ends on directional movement of a localising mRNA./strong

doi: 10.1038/s41594-024-01212-x/span. a href="https://pubmed.ncbi.nlm.nih.gov/38297086/"Pubmed/a/pnpMadan V, Albacete Albacete L, Jin L, Scaturro P, Watson JL, Muschalik ... MAPs, and microtubule ends on directional movement of a localising mRNA./strong

J. F. Zürcher, A. A. Kleefeldt, L. F. H. Funke, J. ... J. L. Watson, S. Aich, B. Oller-Salvia, A. A. Drakek, S.

item fg-type-image fg-idle"figure class="fg-item-inner"a href="https://www2.mrc-lmb.cam.ac.uk/groups/greger/wp-content/uploads/sites/32/398_jake-watson.jpg" ... data-caption-title="Jake Watson" data-attachment-id="102" data-type="image"

619: 555-562./abr /nJ. F. Zuu0308rcher, A. A. Kleefeldt, L. F. H. ... Biol/em/emstrong 2021/strong 220 (2): e202009063./abr /nJ. L. Watson, S. Aich, B.

Day 362 of #LMB365 shows the LMB Executive Committee after a recent meeting. ... Protein samples frozen on grids in amorphous ice are placed inside a nanocap.

cam.ac.uk/dna-discovery-pioneer-james-watson-pays-tribute-colleague-francis-crick/">DNA discovery pioneer James Watson pays tribute to colleague Francis Crick</a></blockquote><iframe sandbox="allow-scripts" ... https://www2.mrc-lmb.cam.ac.uk/wordpress/wp-

cam.ac.uk/photo-archive/reproduction-of-watson-crick-dna-model/">Reproduction of Watson & Crick DNA Model</a></blockquote><iframe sandbox="allow-scripts" security="restricted" ... ac.uk/photo-archive/reproduction-of-watson-crick-dna-model/embed/#?secret=B

cam.ac.uk/photo-archive/jim-watson-outside-the-eagle/">Jim Watson Outside The Eagle</a></blockquote><iframe sandbox="allow-scripts" security="restricted" ... photo-archive/jim-watson-outside-the-eagle/embed/#?secret=rnQgBPIxlK" width="600" height="338"

1.0 MRC Laboratory of Molecular Biology https://www2.mrc-lmb.cam.ac.uk rich 600 338 <blockquote class="wp-embedded-content" data-secret="2xk1MuOGn7"><a ... handful of pseudocoloured hippocampal neurons (brain cells) that have been specifically targeted

1.0 MRC Laboratory of Molecular Biology https://www2.mrc-lmb.cam.ac.uk rich 600 338 <blockquote class="wp-embedded-content" data-secret="iPJZ7szvLZ"><a ... By simulating the activity of individual synapses on a neuron, seen as deflections in this image

base pairing</a></blockquote><iframe sandbox="allow-scripts" security="restricted" ... 182 100 “Nobel laureate Venki Ramakarishnan describes how James Watson discovered DNA base pairing which showed how the DNA double helix could carry.