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  2. The ER membrane protein complex is a transmembrane domain insertase

    https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/Science_2017c.pdf
    27 Jan 2018: In some experiments, nucleased RRL was used. Here, CaCl2 is added to 1 mM and the Ca2+-activated nuclease from S. ... In some reactions, a tripeptide competitive inhibitor of glycosylation (Asn-Tyr-Thr) was added at 50 µM to verify identity of the
  3. doi:10.1016/j.tibs.2006.08.004

    https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/42_Bernstein_HD_TIBS_2006.pdf
    17 Aug 2006: 39]. As a result, a fraction of some proteins (e.g. hepatitis B virus precore and. ... b,c) The cleaved signal peptides of some viral. glycoproteins mediate functions that are essential for the viral life cycle.
  4. Crystal Structure of a Calcium-Phospholipid Binding Domainfrom…

    https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/9430701.pdf
    20 Apr 2002: In addi-tion to calcium, the activation of cPLA2 by some agonists re-quires phosphorylation of the enzyme (7, 8). ... The model showed that the molecular replacement solution hadcorrectly placed the b-sheets, but some loop conformations,
  5. PII: S0962-8924(99)01504-4

    https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/14_Hegde_RS_TCB_1999.pdf
    11 Mar 1999: In the case of some TM domains, the core translo-con might suffice2,25. ... Thus, thecurrently mysterious normal function of PrP, as wellas development of some of its associated diseases35,might be regulated at the level of protein biogenesisand topology.
  6. Nicotinic Acetylcholine Receptor at 4.6 Å Resolution: Transverse…

    https://www2.mrc-lmb.cam.ac.uk/groups/nu/pdf/jmb99.pdf
    15 Sep 2003: A general property of tubular crystals is thatthere is some variation in the helical pitch (ororientation of the surface lattice), even within agiven helical family. ... There are crescents of about seven suchpeaks and some additional tunnel-lining
  7. Cell, Vol. 92, 621–631, March 6, 1998, Copyright 1998 ...

    https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/12_Hegde_RS_Cell_1998.pdf
    28 Feb 1998: cross-linker.served some role in maintaining ribosome binding, then(B) Nascent chain translocation intermediates of pPL-86-mer, pPL-. ... While this still may be the supported by the observation that metabolic conditionsunder which apo B is being
  8. Membrane Localization is Critical for Activation of the PICK1 BAR…

    https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/MadsenGetherTraffic2008.pdf
    18 Oct 2008: PICK1 was distributed equally between the two fractions,. suggesting some constitutive membrane association of. ... some intracellular, vesicular accumulation (Figure 5A). However, upon cotransfection with PICK1, we observed.
  9. refmac 5.8 series

    https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/refmac/bug_fixes.html
    6 Aug 2014: 5.8.0036. Symmetry related restraints. There were some problems with symmetry related external restraints. ... Map sharpening would produce noisy map in some cases. Now sharpening has two components: 1) Removable B value and 2) regularised sharpening B
  10. Crystal Structures of Bacillus subtilis Lon Protease

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/londumanjmb2010.pdf
    20 Jul 2010: dependent protease FtsH, and thus, Lonproteases of the Lon B type fulfil their roles in theseorganisms.22 Some bacteria, such as Thermotogamaritima, Pseudomonas aeruginosa, and Bacillus sub-tilis, express both Lon ... Some of theseinteractions are of a
  11. Prokaryotic cytoskeletons: protein filaments organizing small cells

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/nrmicro.2017.153.pdf
    18 Jan 2018: Division in some cases, others unknown. 14,142,143. CrvA Bacteria Vibrio spp. ... 105,152. PopZ Bacteria Some Gram-negative bacteria. Cell pole marker, signalling hub.

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