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  2. Excellent end of the year - with two papers accepted in December! |…

    https://www.corebioinf.stemcells.cam.ac.uk/news/excellent-end-year-two-papers-accepted-december
    23 Feb 2024: Search site. Core Bioinformatics group. Excellent end of the year - with two papers accepted in December! Submitted by Dr Irina Mohorianu on Wed, 28/12/2022 - 12:26. Two papers were accepted in December! bulkAnalyseR: An accessible, interactive
  3. Single cell RNA-Seq | Core Bioinformatics group

    https://www.corebioinf.stemcells.cam.ac.uk/pipelines-tools/pipelines/single-cell-rna-seq
    23 Feb 2024: Search site. Core Bioinformatics group. Single cell RNA-Seq. Smart-Seq pipeline. Smart-seq and Smart-Seq2 are popular protocols for single-cell RNA-sequencing. With these protocols, 96-well plates are used with individual cells placed in each well.
  4. Analysis of mRNA-Seq alternative splicing | Core Bioinformatics group

    https://www.corebioinf.stemcells.cam.ac.uk/pipelines-tools/pipelines/analysis-mrna-seq-alternative-splicing
    5 Jul 2024: Search site. Core Bioinformatics group. Analysis of mRNA-Seq alternative splicing. Our pipeline uses rMATS to quantify alternative splicing events. rMATS detects five different types of events, as in the figure below. When quantifying events, two
  5. NOTCH1 drives immune-escape mechanisms in B cell malignancies | Core…

    https://www.corebioinf.stemcells.cam.ac.uk/news/notch1-drives-immune-escape-mechanisms-b-cell-malignancies
    5 Jul 2024: Search site. Core Bioinformatics group. NOTCH1 drives immune-escape mechanisms in B cell malignancies. Submitted by Dr Irina Mohorianu on Mon, 03/05/2021 - 06:28. A new paper in collaboration with Dr Ingo Ringshausen has been submitted to biorXiv.
  6. feamiR is presented at the Heidelberg Non-coding genome symposium by…

    https://www.corebioinf.stemcells.cam.ac.uk/news/feamir-presented-heidelberg-non-coding-genome-symposium-eleanor
    5 Jul 2024: Search site. Core Bioinformatics group. feamiR is presented at the Heidelberg Non-coding genome symposium by Eleanor. Submitted by Dr Irina Mohorianu on Thu, 14/10/2021 - 15:34. The feamiR tool, for predicting microRNA/mRNA interactions is presented
  7. Analysis of mRNA-Seq alternative splicing | Core Bioinformatics group

    https://www.corebioinf.stemcells.cam.ac.uk/pipelines-tools/pipelines/analysis-mrna-seq-alternative-splicing
    23 Feb 2024: Search site. Core Bioinformatics group. Analysis of mRNA-Seq alternative splicing. Our pipeline uses rMATS to quantify alternative splicing events. rMATS detects five different types of events, as in the figure below. When quantifying events, two
  8. NOTCH1 drives immune-escape mechanisms in B cell malignancies | Core…

    https://www.corebioinf.stemcells.cam.ac.uk/news/notch1-drives-immune-escape-mechanisms-b-cell-malignancies
    23 Feb 2024: Search site. Core Bioinformatics group. NOTCH1 drives immune-escape mechanisms in B cell malignancies. Submitted by Dr Irina Mohorianu on Mon, 03/05/2021 - 06:28. A new paper in collaboration with Dr Ingo Ringshausen has been submitted to biorXiv.
  9. Defining the transcriptional signature of esophageal-to-skin lineage…

    https://www.corebioinf.stemcells.cam.ac.uk/news/defining-transcriptional-signature-esophageal-skin-lineage-conversion
    5 Jul 2024: Search site. Core Bioinformatics group. Defining the transcriptional signature of esophageal-to-skin lineage conversion. Submitted by Dr Irina Mohorianu on Sun, 28/03/2021 - 16:18. A new paper in collaboration with Dr Maria Alcolea has been
  10. miRNA classification with feamiR | Core Bioinformatics group

    https://www.corebioinf.stemcells.cam.ac.uk/pipelines-tools/tools/mirna-classification-feamir
    5 Jul 2024: Search site. Core Bioinformatics group. miRNA classification with feamiR. microRNAs play a key role in RNA interference, the sequence-driven targeting of mRNAs that regulates their translation to proteins, through translation inhibition or the
  11. feamiR is presented at the Heidelberg Non-coding genome symposium by…

    https://www.corebioinf.stemcells.cam.ac.uk/news/feamir-presented-heidelberg-non-coding-genome-symposium-eleanor
    23 Feb 2024: Search site. Core Bioinformatics group. feamiR is presented at the Heidelberg Non-coding genome symposium by Eleanor. Submitted by Dr Irina Mohorianu on Thu, 14/10/2021 - 15:34. The feamiR tool, for predicting microRNA/mRNA interactions is presented
  12. Defining the transcriptional signature of esophageal-to-skin lineage…

    https://www.corebioinf.stemcells.cam.ac.uk/news/defining-transcriptional-signature-esophageal-skin-lineage-conversion
    23 Feb 2024: Search site. Core Bioinformatics group. Defining the transcriptional signature of esophageal-to-skin lineage conversion. Submitted by Dr Irina Mohorianu on Sun, 28/03/2021 - 16:18. A new paper in collaboration with Dr Maria Alcolea has been
  13. Shiny apps for bulk data with bulkAnalyseR | Core Bioinformatics group

    https://www.corebioinf.stemcells.cam.ac.uk/pipelines-tools/tools/shiny-apps-bulk-data-bulkanalyser
    5 Jul 2024: Moreover, the app can be easily shared and published, incentivising research reproducibility and allowing others to explore the same processed data.
  14. Shiny apps for bulk data with bulkAnalyseR | Core Bioinformatics group

    https://www.corebioinf.stemcells.cam.ac.uk/pipelines-tools/tools/shiny-apps-bulk-data-bulkanalyser
    23 Feb 2024: Moreover, the app can be easily shared and published, incentivising research reproducibility and allowing others to explore the same processed data.
  15. miRNA classification with feamiR | Core Bioinformatics group

    https://www.corebioinf.stemcells.cam.ac.uk/pipelines-tools/tools/mirna-classification-feamir
    23 Feb 2024: Search site. Core Bioinformatics group. miRNA classification with feamiR. microRNAs play a key role in RNA interference, the sequence-driven targeting of mRNAs that regulates their translation to proteins, through translation inhibition or the
  16. Mapping the biogenesis of forward programmed megakaryocytes from…

    https://www.corebioinf.stemcells.cam.ac.uk/news/mapping-biogenesis-forward-programmed-megakaryocytes-induced-pluripotent-stem-cells
    5 Jul 2024: Search site. Core Bioinformatics group. Mapping the biogenesis of forward programmed megakaryocytes from induced pluripotent stem cells. Submitted by Dr Irina Mohorianu on Mon, 03/05/2021 - 12:02. A new paper in collaboration with Dr Cedric Ghevaert
  17. ZAP-70 constitutively regulates gene expression and protein synthesis …

    https://www.corebioinf.stemcells.cam.ac.uk/news/zap-70-constitutively-regulates-gene-expression-and-protein-synthesis-chronic-lymphocytic
    5 Jul 2024: Search site. Core Bioinformatics group. ZAP-70 constitutively regulates gene expression and protein synthesis in chronic lymphocytic leukemia. Submitted by Dr Irina Mohorianu on Sun, 28/03/2021 - 16:14. A new paper in collaboration with Dr Ingo
  18. Mapping the biogenesis of forward programmed megakaryocytes from…

    https://www.corebioinf.stemcells.cam.ac.uk/news/mapping-biogenesis-forward-programmed-megakaryocytes-induced-pluripotent-stem-cells
    23 Feb 2024: Search site. Core Bioinformatics group. Mapping the biogenesis of forward programmed megakaryocytes from induced pluripotent stem cells. Submitted by Dr Irina Mohorianu on Mon, 03/05/2021 - 12:02. A new paper in collaboration with Dr Cedric Ghevaert
  19. The sum of two halves may be different from the whole. Effects of…

    https://www.corebioinf.stemcells.cam.ac.uk/news/sum-two-halves-may-be-different-whole-effects-splitting-sequencing-samples-across-lanes
    5 Jul 2024: Search site. Core Bioinformatics group. The sum of two halves may be different from the whole. Effects of splitting sequencing samples across lanes. Submitted by Dr Irina Mohorianu on Tue, 11/05/2021 - 18:55. A new methods paper from our group was
  20. ZAP-70 constitutively regulates gene expression and protein synthesis …

    https://www.corebioinf.stemcells.cam.ac.uk/news/zap-70-constitutively-regulates-gene-expression-and-protein-synthesis-chronic-lymphocytic
    23 Feb 2024: Search site. Core Bioinformatics group. ZAP-70 constitutively regulates gene expression and protein synthesis in chronic lymphocytic leukemia. Submitted by Dr Irina Mohorianu on Sun, 28/03/2021 - 16:14. A new paper in collaboration with Dr Ingo
  21. The sum of two halves may be different from the whole. Effects of…

    https://www.corebioinf.stemcells.cam.ac.uk/news/sum-two-halves-may-be-different-whole-effects-splitting-sequencing-samples-across-lanes
    23 Feb 2024: Search site. Core Bioinformatics group. The sum of two halves may be different from the whole. Effects of splitting sequencing samples across lanes. Submitted by Dr Irina Mohorianu on Tue, 11/05/2021 - 18:55. A new methods paper from our group was

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