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  2. Teaching material | Core Bioinformatics group

    https://www.corebioinf.stemcells.cam.ac.uk/teaching-material
    23 Feb 2024: Search site. Core Bioinformatics group. Teaching material. Core Bioinformatics group. Teaching. All teaching materials from the Core Bioinformatics group can be found on our GitHub page. CSCI Teaching. Introduction to RNAseq. This repository
  3. KendigSham.jpg | Core Bioinformatics group

    https://www.corebioinf.stemcells.cam.ac.uk/file/kendigshamjpg
    23 Feb 2024: Search site. Core Bioinformatics group. KendigSham.jpg. The truth is rarely pure and never simple. Oscar Wilde, The Importance of Being Earnest. core-bioinformatics-website-1000.png. Wellcome - MRC Cambridge Stem Cell Institute. Jeffrey Cheah
  4. William (Billy) Dunn | Core Bioinformatics group

    https://www.corebioinf.stemcells.cam.ac.uk/staff/william-billy-dunn
    23 Feb 2024: Search site. Core Bioinformatics group. William (Billy) Dunn. BSc (MedSci) (2013). MBChB (Hons) (2015). MSc Bioinformatics (2017). MRCP (2020). PhD in Stem Cell Biology (2022-present). I completed my intercalated BSc, medical degree and MSc at the
  5. ChIP-Seq | Core Bioinformatics group

    https://www.corebioinf.stemcells.cam.ac.uk/pipelines-tools/pipelines/chip-seq
    23 Feb 2024: Search site. Core Bioinformatics group. ChIP-Seq. Chromatin immunoprecipitation sequencing (ChIP-Seq) is used to analyse DNA-protein interactions. It infers the positions in a reference genome that are bound by the protein of interest. The list of
  6. Data | Core Bioinformatics group

    https://www.corebioinf.stemcells.cam.ac.uk/data
    23 Feb 2024: Search site. Core Bioinformatics group. Data. Core Bioinformatics group. Data. Data acquisition, traceability and curation. We operate a strict policy of experimental record-keeping with traceable identifiers for each experiment that are linked to
  7. WilliamDunn.jpg | Core Bioinformatics group

    https://www.corebioinf.stemcells.cam.ac.uk/file/williamdunnjpg
    23 Feb 2024: Search site. Core Bioinformatics group. WilliamDunn.jpg. The truth is rarely pure and never simple. Oscar Wilde, The Importance of Being Earnest. core-bioinformatics-website-1000.png. Wellcome - MRC Cambridge Stem Cell Institute. Jeffrey Cheah
  8. The Noise paper is presented at UKCBCB, NRP by Ilias | Core…

    https://www.corebioinf.stemcells.cam.ac.uk/news/noise-paper-presented-ukcbcb-nrp-ilias
    23 Feb 2024: Institute, Norwich Research Park, UK.
  9. Kendig (Kenny) Sham | Core Bioinformatics group

    https://www.corebioinf.stemcells.cam.ac.uk/staff/kendig-kenny-sham
    23 Feb 2024: My aim is to expand my Machine Learning skills and apply classic and novel approaches on RNA-seq datasets (at bulk and single-cell level) while working as a Research Assistant
  10. Clustering evaluation with ClustAssess | Core Bioinformatics group

    https://www.corebioinf.stemcells.cam.ac.uk/pipelines-tools/tools/clustering-evaluation-clustassess
    23 Feb 2024: Search site. Core Bioinformatics group. Clustering evaluation with ClustAssess. The transition from bulk to single-cell analyses transformed the computational challenges for high-throughput sequencing data processing. At the core of single-cell
  11. LiviuPirvan.png | Core Bioinformatics group

    https://www.corebioinf.stemcells.cam.ac.uk/file/liviupirvanpng
    23 Feb 2024: Search site. Core Bioinformatics group. LiviuPirvan.png. The truth is rarely pure and never simple. Oscar Wilde, The Importance of Being Earnest. core-bioinformatics-website-1000.png. Wellcome - MRC Cambridge Stem Cell Institute. Jeffrey Cheah
  12. Publications | Core Bioinformatics group

    https://www.corebioinf.stemcells.cam.ac.uk/publications
    23 Feb 2024: Search site. Core Bioinformatics group. Publications. Core Bioinformatics group. Publications. Methods papers. 2022. ClustAssess: tools for assessing the robustness of single-cell clustering. Arash Shahsavari, Andi Munteanu, Irina Mohorianu. doi:.
  13. Rafael Kollyfas | Core Bioinformatics group

    https://www.corebioinf.stemcells.cam.ac.uk/staff/rafael-kollyfas
    23 Feb 2024: My primary research interest lies in the application of machine learning in healthcare, particularly in omics.
  14. The Split manuscript is presented at UKCBCB, NRP by Eleanor | Core…

    https://www.corebioinf.stemcells.cam.ac.uk/news/split-manuscript-presented-ukcbcb-nrp-eleanor
    23 Feb 2024: Institute, Norwich Research Park, UK.
  15. feamiR_ega.png | Core Bioinformatics group

    https://www.corebioinf.stemcells.cam.ac.uk/file/feamiregapng
    23 Feb 2024: Search site. Core Bioinformatics group. feamiR_ega.png. Alt Text:. Summary of features selected by eGA on full H. sapiens positive and negative sets. Title Text:. Summary of features selected by eGA on full H. sapiens positive and negative sets. The
  16. Bisulfite sequencing | Core Bioinformatics group

    https://www.corebioinf.stemcells.cam.ac.uk/pipelines-tools/pipelines/bisulfite-sequencing
    23 Feb 2024: Search site. Core Bioinformatics group. Bisulfite sequencing. Bisulfite sequencing (BS) is a technique used to analyse patterns of DNA methylation. As DNA polymerase used in polymerase chain reaction (PCR) during a standard NGS protocol does not
  17. Toby Milne-Clark | Core Bioinformatics group

    https://www.corebioinf.stemcells.cam.ac.uk/staff/toby-milne-clark
    23 Feb 2024: disciplines. Consequently, I studied for an MSc in Statistics and Data Science with the Université Grenoble Alpes during which I worked in multiple Research Assistant roles for various laboratories at the ... I am keen on applying machine learning
  18. AndiMunteanu.png | Core Bioinformatics group

    https://www.corebioinf.stemcells.cam.ac.uk/file/andimunteanupng
    23 Feb 2024: Search site. Core Bioinformatics group. AndiMunteanu.png. The truth is rarely pure and never simple. Oscar Wilde, The Importance of Being Earnest. core-bioinformatics-website-1000.png. Wellcome - MRC Cambridge Stem Cell Institute. Jeffrey Cheah
  19. feamiR - R package for predicting miRNA/mRNA interactions | Core…

    https://www.corebioinf.stemcells.cam.ac.uk/news/feamir-r-package-predicting-mirnamrna-interactions
    23 Feb 2024: Search site. Core Bioinformatics group. feamiR - R package for predicting miRNA/mRNA interactions. Submitted by E. Lauzikaite on Tue, 12/01/2021 - 12:28. Our methods paper on feamiR, an R tool for charaterising and predicting miRNA/mRNA interactions
  20. Bulk mRNA-Seq | Core Bioinformatics group

    https://www.corebioinf.stemcells.cam.ac.uk/pipelines-tools/pipelines/bulk-mrna-seq
    23 Feb 2024: To increase the visibility of CSCI research in the wider community, we create shiny apps for each bulk mRNA-Seq dataset which can be used to explore data and share more
  21. Ilias Moutsopoulos | Core Bioinformatics group

    https://www.corebioinf.stemcells.cam.ac.uk/staff/ilias-moutsopoulos
    23 Feb 2024: I am currently working with dr. Irina Mohorianu as a research assistant at the Cambridge Stem Cell Institute, developing pipelines for the analysis of diverse types of data. ... Nucleic Acids Research. Contact Details. im383 at cam.ac.uk. Available for
  22. miguel_larraz.png | Core Bioinformatics group

    https://www.corebioinf.stemcells.cam.ac.uk/file/miguellarrazpng
    23 Feb 2024: Search site. Core Bioinformatics group. miguel_larraz.png. The truth is rarely pure and never simple. Oscar Wilde, The Importance of Being Earnest. core-bioinformatics-website-1000.png. Wellcome - MRC Cambridge Stem Cell Institute. Jeffrey Cheah
  23. Excellent end of the year - with two papers accepted in December! |…

    https://www.corebioinf.stemcells.cam.ac.uk/news/excellent-end-year-two-papers-accepted-december
    23 Feb 2024: Search site. Core Bioinformatics group. Excellent end of the year - with two papers accepted in December! Submitted by Dr Irina Mohorianu on Wed, 28/12/2022 - 12:26. Two papers were accepted in December! bulkAnalyseR: An accessible, interactive
  24. Analysis of mRNA-Seq alternative splicing | Core Bioinformatics group

    https://www.corebioinf.stemcells.cam.ac.uk/pipelines-tools/pipelines/analysis-mrna-seq-alternative-splicing
    23 Feb 2024: Search site. Core Bioinformatics group. Analysis of mRNA-Seq alternative splicing. Our pipeline uses rMATS to quantify alternative splicing events. rMATS detects five different types of events, as in the figure below. When quantifying events, two
  25. RECOMB_Poster1.jpg | Core Bioinformatics group

    https://www.corebioinf.stemcells.cam.ac.uk/file/recombposter1jpg
    23 Feb 2024: Search site. Core Bioinformatics group. RECOMB_Poster1.jpg. The truth is rarely pure and never simple. Oscar Wilde, The Importance of Being Earnest. core-bioinformatics-website-1000.png. Wellcome - MRC Cambridge Stem Cell Institute. Jeffrey Cheah
  26. Irina Mohorianu | Core Bioinformatics group

    https://www.corebioinf.stemcells.cam.ac.uk/staff/irina-mohorianu
    23 Feb 2024: Nucleic Acids Research. bulkAnalyseR: An accessible, interactive pipeline for analysing and sharing bulk multi-modal sequencing data.
  27. RECOMB_Poster2.jpg | Core Bioinformatics group

    https://www.corebioinf.stemcells.cam.ac.uk/file/recombposter2jpg
    23 Feb 2024: Search site. Core Bioinformatics group. RECOMB_Poster2.jpg. The truth is rarely pure and never simple. Oscar Wilde, The Importance of Being Earnest. core-bioinformatics-website-1000.png. Wellcome - MRC Cambridge Stem Cell Institute. Jeffrey Cheah
  28. NOTCH1 drives immune-escape mechanisms in B cell malignancies | Core…

    https://www.corebioinf.stemcells.cam.ac.uk/news/notch1-drives-immune-escape-mechanisms-b-cell-malignancies
    23 Feb 2024: Search site. Core Bioinformatics group. NOTCH1 drives immune-escape mechanisms in B cell malignancies. Submitted by Dr Irina Mohorianu on Mon, 03/05/2021 - 06:28. A new paper in collaboration with Dr Ingo Ringshausen has been submitted to biorXiv.
  29. Single cell RNA-Seq | Core Bioinformatics group

    https://www.corebioinf.stemcells.cam.ac.uk/pipelines-tools/pipelines/single-cell-rna-seq
    23 Feb 2024: Search site. Core Bioinformatics group. Single cell RNA-Seq. Smart-Seq pipeline. Smart-seq and Smart-Seq2 are popular protocols for single-cell RNA-sequencing. With these protocols, 96-well plates are used with individual cells placed in each well.
  30. Floris Johan Maria Roos | Core Bioinformatics group

    https://www.corebioinf.stemcells.cam.ac.uk/staff/floris-johan-maria-roos
    23 Feb 2024: T.M.A.L. Klem and dr. B.P.L. Wijnhoven) and started conducting research into the bile ducts, resulting in his first publication. ... Ludovic Vallier). Currently, he restarted working at the University of Cambridge as a clinical research fellow as well as
  31. RECOMB_Scripps.jpg | Core Bioinformatics group

    https://www.corebioinf.stemcells.cam.ac.uk/file/recombscrippsjpg
    23 Feb 2024: Search site. Core Bioinformatics group. RECOMB_Scripps.jpg. The truth is rarely pure and never simple. Oscar Wilde, The Importance of Being Earnest. core-bioinformatics-website-1000.png. Wellcome - MRC Cambridge Stem Cell Institute. Jeffrey Cheah
  32. feamiR is presented at the Heidelberg Non-coding genome symposium by…

    https://www.corebioinf.stemcells.cam.ac.uk/news/feamir-presented-heidelberg-non-coding-genome-symposium-eleanor
    23 Feb 2024: Search site. Core Bioinformatics group. feamiR is presented at the Heidelberg Non-coding genome symposium by Eleanor. Submitted by Dr Irina Mohorianu on Thu, 14/10/2021 - 15:34. The feamiR tool, for predicting microRNA/mRNA interactions is presented
  33. feamiR_ffs.png | Core Bioinformatics group

    https://www.corebioinf.stemcells.cam.ac.uk/file/feamirffspng
    23 Feb 2024: Search site. Core Bioinformatics group. feamiR_ffs.png. Alt Text:. Improvement in performance when adding features, ordered on the x-axis, selected by FFS on a subset of the full H. sapiens dataset. Title Text:. Improvement in performance when
  34. Eleanor Williams | Core Bioinformatics group

    https://www.corebioinf.stemcells.cam.ac.uk/staff/eleanor-williams
    23 Feb 2024: Presented as a poster at RECOMB 2022 (Conference on Research in Computational Molecular Biology) at University of California San Diego, USA. ... Nucleic Acids Research. feamiR: Feature selection based on Genetic Algorithms for predicting miRNA-mRNA
  35. rafaelkollyfas.jpg | Core Bioinformatics group

    https://www.corebioinf.stemcells.cam.ac.uk/file/rafaelkollyfasjpg
    23 Feb 2024: Search site. Core Bioinformatics group. rafaelkollyfas.jpg. The truth is rarely pure and never simple. Oscar Wilde, The Importance of Being Earnest. core-bioinformatics-website-1000.png. Wellcome - MRC Cambridge Stem Cell Institute. Jeffrey Cheah
  36. Defining the transcriptional signature of esophageal-to-skin lineage…

    https://www.corebioinf.stemcells.cam.ac.uk/news/defining-transcriptional-signature-esophageal-skin-lineage-conversion
    23 Feb 2024: Search site. Core Bioinformatics group. Defining the transcriptional signature of esophageal-to-skin lineage conversion. Submitted by Dr Irina Mohorianu on Sun, 28/03/2021 - 16:18. A new paper in collaboration with Dr Maria Alcolea has been
  37. Shiny apps for bulk data with bulkAnalyseR | Core Bioinformatics group

    https://www.corebioinf.stemcells.cam.ac.uk/pipelines-tools/tools/shiny-apps-bulk-data-bulkanalyser
    23 Feb 2024: Moreover, the app can be easily shared and published, incentivising research reproducibility and allowing others to explore the same processed data.
  38. AlexCalderwood.jpg | Core Bioinformatics group

    https://www.corebioinf.stemcells.cam.ac.uk/file/alexcalderwoodjpg
    23 Feb 2024: Search site. Core Bioinformatics group. AlexCalderwood.jpg. The truth is rarely pure and never simple. Oscar Wilde, The Importance of Being Earnest. core-bioinformatics-website-1000.png. Wellcome - MRC Cambridge Stem Cell Institute. Jeffrey Cheah
  39. christmas2023_1.jpg | Core Bioinformatics group

    https://www.corebioinf.stemcells.cam.ac.uk/file/christmas20231jpg
    23 Feb 2024: Search site. Core Bioinformatics group. christmas2023_1.jpg. The truth is rarely pure and never simple. Oscar Wilde, The Importance of Being Earnest. core-bioinformatics-website-1000.png. Wellcome - MRC Cambridge Stem Cell Institute. Jeffrey Cheah
  40. Mapping the biogenesis of forward programmed megakaryocytes from…

    https://www.corebioinf.stemcells.cam.ac.uk/news/mapping-biogenesis-forward-programmed-megakaryocytes-induced-pluripotent-stem-cells
    23 Feb 2024: Search site. Core Bioinformatics group. Mapping the biogenesis of forward programmed megakaryocytes from induced pluripotent stem cells. Submitted by Dr Irina Mohorianu on Mon, 03/05/2021 - 12:02. A new paper in collaboration with Dr Cedric Ghevaert
  41. christmas2023_2.jpg | Core Bioinformatics group

    https://www.corebioinf.stemcells.cam.ac.uk/file/christmas20232jpg
    23 Feb 2024: Search site. Core Bioinformatics group. christmas2023_2.jpg. The truth is rarely pure and never simple. Oscar Wilde, The Importance of Being Earnest. core-bioinformatics-website-1000.png. Wellcome - MRC Cambridge Stem Cell Institute. Jeffrey Cheah
  42. miRNA classification with feamiR | Core Bioinformatics group

    https://www.corebioinf.stemcells.cam.ac.uk/pipelines-tools/tools/mirna-classification-feamir
    23 Feb 2024: Search site. Core Bioinformatics group. miRNA classification with feamiR. microRNAs play a key role in RNA interference, the sequence-driven targeting of mRNAs that regulates their translation to proteins, through translation inhibition or the
  43. cristianbulgaru.png | Core Bioinformatics group

    https://www.corebioinf.stemcells.cam.ac.uk/file/cristianbulgarupng
    23 Feb 2024: Search site. Core Bioinformatics group. cristianbulgaru.png. The truth is rarely pure and never simple. Oscar Wilde, The Importance of Being Earnest. core-bioinformatics-website-1000.png. Wellcome - MRC Cambridge Stem Cell Institute. Jeffrey Cheah
  44. ZAP-70 constitutively regulates gene expression and protein synthesis …

    https://www.corebioinf.stemcells.cam.ac.uk/news/zap-70-constitutively-regulates-gene-expression-and-protein-synthesis-chronic-lymphocytic
    23 Feb 2024: Search site. Core Bioinformatics group. ZAP-70 constitutively regulates gene expression and protein synthesis in chronic lymphocytic leukemia. Submitted by Dr Irina Mohorianu on Sun, 28/03/2021 - 16:14. A new paper in collaboration with Dr Ingo
  45. eleanor_williams.jpg | Core Bioinformatics group

    https://www.corebioinf.stemcells.cam.ac.uk/file/eleanorwilliamsjpg
    23 Feb 2024: Search site. Core Bioinformatics group. eleanor_williams.jpg. The truth is rarely pure and never simple. Oscar Wilde, The Importance of Being Earnest. core-bioinformatics-website-1000.png. Wellcome - MRC Cambridge Stem Cell Institute. Jeffrey Cheah
  46. arash_shahsavari.jpg | Core Bioinformatics group

    https://www.corebioinf.stemcells.cam.ac.uk/file/arashshahsavarijpg
    23 Feb 2024: Search site. Core Bioinformatics group. arash_shahsavari.jpg. The truth is rarely pure and never simple. Oscar Wilde, The Importance of Being Earnest. core-bioinformatics-website-1000.png. Wellcome - MRC Cambridge Stem Cell Institute. Jeffrey Cheah
  47. The sum of two halves may be different from the whole. Effects of…

    https://www.corebioinf.stemcells.cam.ac.uk/news/sum-two-halves-may-be-different-whole-effects-splitting-sequencing-samples-across-lanes
    23 Feb 2024: Search site. Core Bioinformatics group. The sum of two halves may be different from the whole. Effects of splitting sequencing samples across lanes. Submitted by Dr Irina Mohorianu on Tue, 11/05/2021 - 18:55. A new methods paper from our group was
  48. feamiRworkflow.png | Core Bioinformatics group

    https://www.corebioinf.stemcells.cam.ac.uk/file/feamirworkflowpng
    23 Feb 2024: Search site. Core Bioinformatics group. feamiRworkflow.png. Alt Text:. Overview of the feamiR workflow. Title Text:. Overview of the feamiR workflow. The truth is rarely pure and never simple. Oscar Wilde, The Importance of Being Earnest.
  49. feamiR_rf_gini.png | Core Bioinformatics group

    https://www.corebioinf.stemcells.cam.ac.uk/file/feamirrfginipng
    23 Feb 2024: Search site. Core Bioinformatics group. feamiR_rf_gini.png. Alt Text:. Boxplot showing distribution of mean decrease in Gini index of features across 100 runs on different subsamples of the full H. sapiens dataset. Title Text:. Boxplot showing
  50. BletchleyFeb2023_1.png | Core Bioinformatics group

    https://www.corebioinf.stemcells.cam.ac.uk/file/bletchleyfeb20231png
    23 Feb 2024: Search site. Core Bioinformatics group. BletchleyFeb2023_1.png. The truth is rarely pure and never simple. Oscar Wilde, The Importance of Being Earnest. core-bioinformatics-website-1000.png. Wellcome - MRC Cambridge Stem Cell Institute. Jeffrey
  51. bulk_rnaseq_jaccard.png | Core Bioinformatics group

    https://www.corebioinf.stemcells.cam.ac.uk/file/bulkrnaseqjaccardpng
    23 Feb 2024: Search site. Core Bioinformatics group. bulk_rnaseq_jaccard.png. The truth is rarely pure and never simple. Oscar Wilde, The Importance of Being Earnest. core-bioinformatics-website-1000.png. Wellcome - MRC Cambridge Stem Cell Institute. Jeffrey

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