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23 Feb 2024: The Institute is a world-leading centre for stem cell research. The Institute is funded by Wellcome and the Medical Research Council.

23 Feb 2024: Search site. Core Bioinformatics group. Tools. Tools. The truth is rarely pure and never simple. Oscar Wilde, The Importance of Being Earnest. core-bioinformatics-website-1000.png. Wellcome - MRC Cambridge Stem Cell Institute. Jeffrey Cheah

23 Feb 2024: Search site. Core Bioinformatics group. i2.png. The truth is rarely pure and never simple. Oscar Wilde, The Importance of Being Earnest. core-bioinformatics-website-1000.png. Wellcome - MRC Cambridge Stem Cell Institute. Jeffrey Cheah Biomedical

23 Feb 2024: Search site. Core Bioinformatics group. noisyR. Submitted by Dr Irina Mohorianu on Mon, 18/01/2021 - 07:56. NoisyR is now submitted to biorXiv. noisyR: Enhancing biological signal in sequencing datasets by characterising random technical noise. the

23 Feb 2024: Search site. Core Bioinformatics group. E. Lauzikaite. Real name:. Name:. E. Lauzikaite. History. Member for. 3 years 8 months. The truth is rarely pure and never simple. Oscar Wilde, The Importance of Being Earnest.

23 Feb 2024: Search site. Core Bioinformatics group. Dorin Miron. MSc and BSc Computer Science. I graduated BSc and MSc in Computer Science from Cuza University in Iasi, Romania. Starting with a deep interest in programming and software engineering, I further

23 Feb 2024: Research Park, UK. ... Norwich Research Park, UK.

23 Feb 2024: Search site. Core Bioinformatics group. i1.png. The truth is rarely pure and never simple. Oscar Wilde, The Importance of Being Earnest. core-bioinformatics-website-1000.png. Wellcome - MRC Cambridge Stem Cell Institute. Jeffrey Cheah Biomedical

23 Feb 2024: Search site. Core Bioinformatics group. Pipelines. Pipelines. mRNA-Seq. mRNA-Seq alternative splicing. ChIP-Seq. scRNA-Seq. bisulfite-Seq. Nextflow. The truth is rarely pure and never simple. Oscar Wilde, The Importance of Being Earnest.

23 Feb 2024: Search site. Core Bioinformatics group. ClustAssess. Submitted by Dr Irina Mohorianu on Sat, 10/04/2021 - 08:41. A new R package, ClustAssess, developed in the group is available on CRAN. with further info on our github:. Well done, Arash! The truth

23 Feb 2024: Search site. Core Bioinformatics group. Dr Irina Mohorianu. Real name:. Name:. Dr Irina Mohorianu. History. Member for. 3 years 9 months. The truth is rarely pure and never simple. Oscar Wilde, The Importance of Being Earnest.

23 Feb 2024: My MSc research project was focused on building a pipeline for Targeted NGS reads in a gene panel for Colorectal cancer; these were summarised in features for the data-driven prediction ... During this initial research, I got interested in understanding

23 Feb 2024: Search site. Core Bioinformatics group. Pipelines & Tools. Core Bioinformatics group. Pipelines & Tools. Pipelines in use. mRNA-Seq. mRNA-Seq alternative splicing. ChIP-Seq. scRNA-Seq. bisulfite-Seq. Nextflow. Tools we are developing. The truth is

23 Feb 2024: Search site. Core Bioinformatics group. g78067.png. The truth is rarely pure and never simple. Oscar Wilde, The Importance of Being Earnest. core-bioinformatics-website-1000.png. Wellcome - MRC Cambridge Stem Cell Institute. Jeffrey Cheah Biomedical

23 Feb 2024: Search site. Core Bioinformatics group. Welcome Toby! Submitted by Dr Irina Mohorianu on Mon, 03/05/2021 - 06:29. We welcome a new member of the group - Toby Milne Clark! The truth is rarely pure and never simple. Oscar Wilde, The Importance of

23 Feb 2024: Search site. Core Bioinformatics group. Liviu Pirvan. PhD Medical Science. MRes Machine Learning. BEng Computer Science. I completed my BEng in Computer Science at the University of York, my MRes in Machine Learning at Imperial College London, and

23 Feb 2024: Search site. Core Bioinformatics group. Nextflow. enables scalable and reproducible scientific workflows using software containers. It allows the adaptation of pipelines written in the most common scripting languages. Nextflow is becoming a powerful

23 Feb 2024: Search site. Core Bioinformatics group. Contact us. Core Bioinformatics group. Contact us. We are based here:. Wellcome - MRC Cambridge Stem Cell Institute. Jeffrey Cheah Biomedical Centre. Puddicombe Way. Cambridge, CB2 0AW. Irina Mohorianu, Head

23 Feb 2024: Search site. Core Bioinformatics group. chipseq.png. The truth is rarely pure and never simple. Oscar Wilde, The Importance of Being Earnest. core-bioinformatics-website-1000.png. Wellcome - MRC Cambridge Stem Cell Institute. Jeffrey Cheah

23 Feb 2024: Lauzikaite on Thu, 04/02/2021 - 16:02. A Research Assistant/Associate - Bioinformatician position has opened in our lab!

23 Feb 2024: This MSc balances taught modules and research; for the latter, over the last year, I focused on the topic of clustering stability on biological data (single cell high throughput expression data).

23 Feb 2024: Search site. Core Bioinformatics group. Image processing. We are developing an imaging processing pipeline which would help us achieve the 3D localization of the fluorescent molecules analysed with the DHPSF microscope. The video is first stacked

23 Feb 2024: Research Assistants, prospective PhD students and Research Associates are welcome. The truth is rarely pure and never simple.

23 Feb 2024: Search site. Core Bioinformatics group. workflow.png. Alt Text:. Workflow diagram of the noisyR pipeline. Title Text:. Workflow diagram of the noisyR pipeline. The truth is rarely pure and never simple. Oscar Wilde, The Importance of Being Earnest.

23 Feb 2024: Search site. Core Bioinformatics group. Cristian Bulgaru. MSc Artificial Intelligence and Optimization (2022-). Data Science Starter Program (2022-2023). Currently enrolled in the Artificial Intelligence and Optimization MSc program at University A.

23 Feb 2024: Search site. Core Bioinformatics group. ClustAssess is on biorxiv! Submitted by Dr Irina Mohorianu on Fri, 04/02/2022 - 06:24. A new preprint (describing ClustAssess) is on bioarxiv:. “ClustAssess: tools for assessing the robustness of single-cell

23 Feb 2024: Search site. Core Bioinformatics group. Cell classification. The semi-supervised cell classification project is based on a sequencing input. The task is the classification of the cells according to external labels (in this context the labels are

23 Feb 2024: Search site. Core Bioinformatics group. Photos. Core Bioinformatics group. Photos. Christmas 2023 at King's College. Christmas at King's College December 2023; bottom row: Friedrich, Rafael, top row: Cameron, Irina, Miguel, Eleanor. Christmas at King

23 Feb 2024: Search site. Core Bioinformatics group. bisulfite.png. The truth is rarely pure and never simple. Oscar Wilde, The Importance of Being Earnest. core-bioinformatics-website-1000.png. Wellcome - MRC Cambridge Stem Cell Institute. Jeffrey Cheah

23 Feb 2024: Before working at the CSCI I was a post-doc at the John Innes Centre, Norwich Research Park, UK, where I worked on comparative transcriptomics over plant development.

23 Feb 2024: Search site. Core Bioinformatics group. bulkAnalyseR is on biorxiv! Submitted by Dr Irina Mohorianu on Fri, 04/02/2022 - 06:20. A new preprint (describing bulkAnalyseR) is on bioarxiv:. “bulkAnalyseR: An accessible, interactive pipeline for

23 Feb 2024: Search site. Core Bioinformatics group. Index sort data. For the optimisation of FACS-sorted cell cultures, we have generated a pipeline identifying discriminative genes from index sort data. The pipeline uses the depth distribution of features in

23 Feb 2024: Search site. Core Bioinformatics group. imohorianu.jpg. The truth is rarely pure and never simple. Oscar Wilde, The Importance of Being Earnest. core-bioinformatics-website-1000.png. Wellcome - MRC Cambridge Stem Cell Institute. Jeffrey Cheah

23 Feb 2024: Research Assistant (2022 - ). MPhil Student in Health Data Science (2022- ); Primary supervisor: Irina Mohorianu. ... Chenge (Joanna) Du (December 2022 - July 2023) Research Assistant, Cambridge Cancer Institute, CRUK.

23 Feb 2024: Search site. Core Bioinformatics group. Cameron Crawford. I started my Bachelor's degree in Computer Science at the University of Cambridge in 2021 and joined the Core Bioinformatics group as an intern at the end of my first year. Throughout my

23 Feb 2024: Search site. Core Bioinformatics group. noisyR is now published in NAR. Submitted by Dr Irina Mohorianu on Sun, 04/07/2021 - 15:35. Illias' paper was acceped in NAR! Well done, Ilias! noisyR: Enhancing biological signal in sequencing datasets by

23 Feb 2024: Search site. Core Bioinformatics group. ChIP-Seq. Chromatin immunoprecipitation sequencing (ChIP-Seq) is used to analyse DNA-protein interactions. It infers the positions in a reference genome that are bound by the protein of interest. The list of

23 Feb 2024: Search site. Core Bioinformatics group. dorinmiron.jpg. The truth is rarely pure and never simple. Oscar Wilde, The Importance of Being Earnest. core-bioinformatics-website-1000.png. Wellcome - MRC Cambridge Stem Cell Institute. Jeffrey Cheah

23 Feb 2024: Search site. Core Bioinformatics group. Data. Core Bioinformatics group. Data. Data acquisition, traceability and curation. We operate a strict policy of experimental record-keeping with traceable identifiers for each experiment that are linked to

23 Feb 2024: Search site. Core Bioinformatics group. Arash Shahsavari. MSc Complex Adaptive Systems (2019). In 2019 I finished my master’s studies at Chalmers University of Technology, in Gothenburg, Sweden, with a thesis on single-cell RNA-seq clustering and

23 Feb 2024: Search site. Core Bioinformatics group. We welcome Alex and Andi! Submitted by Dr Irina Mohorianu on Sun, 04/07/2021 - 15:37. We welcome Alex Calderwood (post-doc) and Andi Munteanu (intern) to the group. We're looking forward to some interesting

23 Feb 2024: Search site. Core Bioinformatics group. KendigSham.jpg. The truth is rarely pure and never simple. Oscar Wilde, The Importance of Being Earnest. core-bioinformatics-website-1000.png. Wellcome - MRC Cambridge Stem Cell Institute. Jeffrey Cheah

23 Feb 2024: Search site. Core Bioinformatics group. Data denoising with noisyR. The NoisyR manuscript was accepted to Nucleic Acids Research (June 2021)!

23 Feb 2024: My primary research interest lies in the application of machine learning in healthcare, particularly in omics.

23 Feb 2024: Search site. Core Bioinformatics group. Teaching material. Core Bioinformatics group. Teaching. All teaching materials from the Core Bioinformatics group can be found on our GitHub page. CSCI Teaching. Introduction to RNAseq. This repository

23 Feb 2024: Search site. Core Bioinformatics group. feamiR_ega.png. Alt Text:. Summary of features selected by eGA on full H. sapiens positive and negative sets. Title Text:. Summary of features selected by eGA on full H. sapiens positive and negative sets. The

23 Feb 2024: Institute, Norwich Research Park, UK.

23 Feb 2024: Search site. Core Bioinformatics group. William (Billy) Dunn. BSc (MedSci) (2013). MBChB (Hons) (2015). MSc Bioinformatics (2017). MRCP (2020). PhD in Stem Cell Biology (2022-present). I completed my intercalated BSc, medical degree and MSc at the

23 Feb 2024: Search site. Core Bioinformatics group. Bisulfite sequencing. Bisulfite sequencing (BS) is a technique used to analyse patterns of DNA methylation. As DNA polymerase used in polymerase chain reaction (PCR) during a standard NGS protocol does not

23 Feb 2024: Search site. Core Bioinformatics group. Publications. Core Bioinformatics group. Publications. Methods papers. 2022. ClustAssess: tools for assessing the robustness of single-cell clustering. Arash Shahsavari, Andi Munteanu, Irina Mohorianu. doi:.