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feamiR is presented at the Heidelberg Non-coding genome symposium by…
https://www.corebioinf.stemcells.cam.ac.uk/news/feamir-presented-heidelberg-non-coding-genome-symposium-eleanor27 Jul 2024: Search site. Core Bioinformatics group. feamiR is presented at the Heidelberg Non-coding genome symposium by Eleanor. Submitted by Dr Irina Mohorianu on Thu, 14/10/2021 - 15:34. The feamiR tool, for predicting microRNA/mRNA interactions is presented -
Clustering evaluation with ClustAssess | Core Bioinformatics group
https://www.corebioinf.stemcells.cam.ac.uk/pipelines-tools/tools/clustering-evaluation-clustassess23 Feb 2024: Search site. Core Bioinformatics group. Clustering evaluation with ClustAssess. The transition from bulk to single-cell analyses transformed the computational challenges for high-throughput sequencing data processing. At the core of single-cell -
feamiR - R package for predicting miRNA/mRNA interactions | Core…
https://www.corebioinf.stemcells.cam.ac.uk/news/feamir-r-package-predicting-mirnamrna-interactions23 Feb 2024: Search site. Core Bioinformatics group. feamiR - R package for predicting miRNA/mRNA interactions. Submitted by E. Lauzikaite on Tue, 12/01/2021 - 12:28. Our methods paper on feamiR, an R tool for charaterising and predicting miRNA/mRNA interactions -
Defining the transcriptional signature of esophageal-to-skin lineage…
https://www.corebioinf.stemcells.cam.ac.uk/news/defining-transcriptional-signature-esophageal-skin-lineage-conversion27 Jul 2024: Search site. Core Bioinformatics group. Defining the transcriptional signature of esophageal-to-skin lineage conversion. Submitted by Dr Irina Mohorianu on Sun, 28/03/2021 - 16:18. A new paper in collaboration with Dr Maria Alcolea has been -
Excellent end of the year - with two papers accepted in December! |…
https://www.corebioinf.stemcells.cam.ac.uk/news/excellent-end-year-two-papers-accepted-december23 Feb 2024: Search site. Core Bioinformatics group. Excellent end of the year - with two papers accepted in December! Submitted by Dr Irina Mohorianu on Wed, 28/12/2022 - 12:26. Two papers were accepted in December! bulkAnalyseR: An accessible, interactive -
Single cell RNA-Seq | Core Bioinformatics group
https://www.corebioinf.stemcells.cam.ac.uk/pipelines-tools/pipelines/single-cell-rna-seq23 Feb 2024: Search site. Core Bioinformatics group. Single cell RNA-Seq. Smart-Seq pipeline. Smart-seq and Smart-Seq2 are popular protocols for single-cell RNA-sequencing. With these protocols, 96-well plates are used with individual cells placed in each well. -
miRNA classification with feamiR | Core Bioinformatics group
https://www.corebioinf.stemcells.cam.ac.uk/pipelines-tools/tools/mirna-classification-feamir27 Jul 2024: Search site. Core Bioinformatics group. miRNA classification with feamiR. microRNAs play a key role in RNA interference, the sequence-driven targeting of mRNAs that regulates their translation to proteins, through translation inhibition or the -
Shiny apps for bulk data with bulkAnalyseR | Core Bioinformatics group
https://www.corebioinf.stemcells.cam.ac.uk/pipelines-tools/tools/shiny-apps-bulk-data-bulkanalyser27 Jul 2024: Moreover, the app can be easily shared and published, incentivising research reproducibility and allowing others to explore the same processed data. -
Analysis of mRNA-Seq alternative splicing | Core Bioinformatics group
https://www.corebioinf.stemcells.cam.ac.uk/pipelines-tools/pipelines/analysis-mrna-seq-alternative-splicing23 Feb 2024: Search site. Core Bioinformatics group. Analysis of mRNA-Seq alternative splicing. Our pipeline uses rMATS to quantify alternative splicing events. rMATS detects five different types of events, as in the figure below. When quantifying events, two -
NOTCH1 drives immune-escape mechanisms in B cell malignancies | Core…
https://www.corebioinf.stemcells.cam.ac.uk/news/notch1-drives-immune-escape-mechanisms-b-cell-malignancies23 Feb 2024: Search site. Core Bioinformatics group. NOTCH1 drives immune-escape mechanisms in B cell malignancies. Submitted by Dr Irina Mohorianu on Mon, 03/05/2021 - 06:28. A new paper in collaboration with Dr Ingo Ringshausen has been submitted to biorXiv. -
Mapping the biogenesis of forward programmed megakaryocytes from…
https://www.corebioinf.stemcells.cam.ac.uk/news/mapping-biogenesis-forward-programmed-megakaryocytes-induced-pluripotent-stem-cells27 Jul 2024: Search site. Core Bioinformatics group. Mapping the biogenesis of forward programmed megakaryocytes from induced pluripotent stem cells. Submitted by Dr Irina Mohorianu on Mon, 03/05/2021 - 12:02. A new paper in collaboration with Dr Cedric Ghevaert -
feamiR is presented at the Heidelberg Non-coding genome symposium by…
https://www.corebioinf.stemcells.cam.ac.uk/news/feamir-presented-heidelberg-non-coding-genome-symposium-eleanor23 Feb 2024: Search site. Core Bioinformatics group. feamiR is presented at the Heidelberg Non-coding genome symposium by Eleanor. Submitted by Dr Irina Mohorianu on Thu, 14/10/2021 - 15:34. The feamiR tool, for predicting microRNA/mRNA interactions is presented -
Defining the transcriptional signature of esophageal-to-skin lineage…
https://www.corebioinf.stemcells.cam.ac.uk/news/defining-transcriptional-signature-esophageal-skin-lineage-conversion23 Feb 2024: Search site. Core Bioinformatics group. Defining the transcriptional signature of esophageal-to-skin lineage conversion. Submitted by Dr Irina Mohorianu on Sun, 28/03/2021 - 16:18. A new paper in collaboration with Dr Maria Alcolea has been -
ZAP-70 constitutively regulates gene expression and protein synthesis …
https://www.corebioinf.stemcells.cam.ac.uk/news/zap-70-constitutively-regulates-gene-expression-and-protein-synthesis-chronic-lymphocytic27 Jul 2024: Search site. Core Bioinformatics group. ZAP-70 constitutively regulates gene expression and protein synthesis in chronic lymphocytic leukemia. Submitted by Dr Irina Mohorianu on Sun, 28/03/2021 - 16:14. A new paper in collaboration with Dr Ingo -
Shiny apps for bulk data with bulkAnalyseR | Core Bioinformatics group
https://www.corebioinf.stemcells.cam.ac.uk/pipelines-tools/tools/shiny-apps-bulk-data-bulkanalyser23 Feb 2024: Moreover, the app can be easily shared and published, incentivising research reproducibility and allowing others to explore the same processed data. -
miRNA classification with feamiR | Core Bioinformatics group
https://www.corebioinf.stemcells.cam.ac.uk/pipelines-tools/tools/mirna-classification-feamir23 Feb 2024: Search site. Core Bioinformatics group. miRNA classification with feamiR. microRNAs play a key role in RNA interference, the sequence-driven targeting of mRNAs that regulates their translation to proteins, through translation inhibition or the -
The sum of two halves may be different from the whole. Effects of…
https://www.corebioinf.stemcells.cam.ac.uk/news/sum-two-halves-may-be-different-whole-effects-splitting-sequencing-samples-across-lanes27 Jul 2024: Search site. Core Bioinformatics group. The sum of two halves may be different from the whole. Effects of splitting sequencing samples across lanes. Submitted by Dr Irina Mohorianu on Tue, 11/05/2021 - 18:55. A new methods paper from our group was -
Mapping the biogenesis of forward programmed megakaryocytes from…
https://www.corebioinf.stemcells.cam.ac.uk/news/mapping-biogenesis-forward-programmed-megakaryocytes-induced-pluripotent-stem-cells23 Feb 2024: Search site. Core Bioinformatics group. Mapping the biogenesis of forward programmed megakaryocytes from induced pluripotent stem cells. Submitted by Dr Irina Mohorianu on Mon, 03/05/2021 - 12:02. A new paper in collaboration with Dr Cedric Ghevaert -
ZAP-70 constitutively regulates gene expression and protein synthesis …
https://www.corebioinf.stemcells.cam.ac.uk/news/zap-70-constitutively-regulates-gene-expression-and-protein-synthesis-chronic-lymphocytic23 Feb 2024: Search site. Core Bioinformatics group. ZAP-70 constitutively regulates gene expression and protein synthesis in chronic lymphocytic leukemia. Submitted by Dr Irina Mohorianu on Sun, 28/03/2021 - 16:14. A new paper in collaboration with Dr Ingo -
The sum of two halves may be different from the whole. Effects of…
https://www.corebioinf.stemcells.cam.ac.uk/news/sum-two-halves-may-be-different-whole-effects-splitting-sequencing-samples-across-lanes23 Feb 2024: Search site. Core Bioinformatics group. The sum of two halves may be different from the whole. Effects of splitting sequencing samples across lanes. Submitted by Dr Irina Mohorianu on Tue, 11/05/2021 - 18:55. A new methods paper from our group was
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