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Unknome v3
https://unknome.mrc-lmb.cam.ac.uk/cluster_details/UKP07752/intrinsic apoptotic signaling pathway by p53 class mediator. ... 1) (KCP-1) (P53-induced protein PIGPC1) (Transmembrane protein THW). None. GO (18). -
Unknome v3
https://unknome.mrc-lmb.cam.ac.uk/cluster_details/UKP07752/0/intrinsic apoptotic signaling pathway by p53 class mediator. ... InterPro (2). 0.0. P53 apoptosis effector related to PMP22. None. GO (3). -
Unknome v3
https://unknome.mrc-lmb.cam.ac.uk/cluster_details/UKP07752/1/intrinsic apoptotic signaling pathway by p53 class mediator. ... None. GO (21). InterPro (2). 2.9. fk24g11. P53 apoptosis effector related to. -
Search Publications | Publications
https://publications.ch.cam.ac.uk/publications-search?page=40128 Jun 2024: Search site. Publications. Uploading Images. Members of the Department can attach an image to a publication by clicking on the title of the publication in the listing below. Please note: all images attached to a publication will be visible on -
Unknome v3
https://unknome.mrc-lmb.cam.ac.uk/cluster_details/UKP07752/3/intrinsic apoptotic signaling pathway by p53 class mediator. ... InterPro (1). 0.0. P53 apoptosis effector related to PMP22. None. GO (6). -
Unknome v3
https://unknome.mrc-lmb.cam.ac.uk/cluster_details/UKP07752/4/intrinsic apoptotic signaling pathway by p53 class mediator. ... EMBL (2). InterPro (2). 0.0. P53 apoptosis effector related to PMP-22. -
Unknome v3
https://unknome.mrc-lmb.cam.ac.uk/cluster_details/UKP07752/5/intrinsic apoptotic signaling pathway by p53 class mediator. ... GO (3). InterPro (2). 0.0. P53 apoptosis effector related to PMP-22. -
Synthetic biology: applications come of age
https://haseloff.plantsci.cam.ac.uk/resources/Part2SynBio_refs/Lecture-3/Khalil2010.pdf14 Aug 2023: For instance, adeno-viruses were programmed to couple their replication to the state of the p53 pathway in human cells93. ... Normal p53 production would result in inhibition of a crucial viral replication component, whereas a defunct p53 pathway, which -
Unknome v3
https://unknome.mrc-lmb.cam.ac.uk/cluster_details/UKP07752/6/intrinsic apoptotic signaling pathway by p53 class mediator. ... 1) (KCP-1) (P53-induced protein PIGPC1) (Transmembrane protein THW). None. GO (18). -
Unknome v3
https://unknome.mrc-lmb.cam.ac.uk/cluster_details/UKP07752/7/intrinsic apoptotic signaling pathway by p53 class mediator. ... 0.0. P53 apoptosis effector related to PMP22. None. GO (3). EMBL (2). -
p53 impairs CRISPR/Cas9 in healthy cells | Department of Biochemistry
https://www.bioc.cam.ac.uk/news/archive/2018/p53-impairs-crispr-cas9-in-healthy-cells29 Jun 2024: RPE-1) cell line activate p53, causing cell growth arrest and DNA repair via the NHEJ pathway. ... These results suggest that CRISPR/Cas9 selects against cells with a functional p53 pathway, which can explain the higher efficiency of CRISPR/Cas9 in -
Extra centrosomes and cancer : New light on a century old problem |…
https://www.gen.cam.ac.uk/news/coelho-extra-centrosomes-and-cancer29 Jun 2024: p53 is non-functional in the majority of human tumours and mice lacking p53 are prone to tumour development. ... p53 surveillance pathway. -
Table Legend
https://www.mrc-mbu.cam.ac.uk/files/impi-2020-q3pre.xlsx1 Oct 2021: Table Legend. Supplementary Data: IMPI. Data sets for protein-encoding human genes in Ensembl. Annotation includes: Evidence of subcellular localisation; Manual curation of literature; IMPI localisation score for likelihood of a mitochondrial -
Legend
https://www.mrc-mbu.cam.ac.uk/files/buddy-2021q4-20211001-dist_0.xlsx4 Oct 2021: Lack of aprataxin impairs mitochondrial functions via downregulation of the APE1/NRF1/NRF2 pathway [PMID:25976310]; Coenzyme Q deficiency and cerebellar ataxia associated with an aprataxin mutation [PMID:15699391]; Aprataxin localizes ... A Novel Inborn -
Unknome v3
https://unknome.mrc-lmb.cam.ac.uk/cluster_details/UKP07752/1/1intrinsic apoptotic signaling pathway by p53 class mediator. ... None. GO (21). InterPro (2). 2.9. fk24g11. P53 apoptosis effector related to. -
Legend
https://www.mrc-mbu.cam.ac.uk/files/impi-2021-q4pre-20211001-dist_0.xlsx4 Oct 2021: pathway, causing early-onset fatal hypertrophic cardiomyopathy [PMID:12474143]; IMM. -
Unknome v3
https://unknome.mrc-lmb.cam.ac.uk/cluster_details/UKP07752/3/1intrinsic apoptotic signaling pathway by p53 class mediator. ... 1) (KCP-1) (P53-induced protein PIGPC1) (Transmembrane protein THW). None. GO (18). -
Unknome v3
https://unknome.mrc-lmb.cam.ac.uk/cluster_details/UKP07752/4/1intrinsic apoptotic signaling pathway by p53 class mediator. ... 1) (KCP-1) (P53-induced protein PIGPC1) (Transmembrane protein THW). None. GO (18). -
Unknome v3
https://unknome.mrc-lmb.cam.ac.uk/cluster_details/UKP07752/5/1intrinsic apoptotic signaling pathway by p53 class mediator. ... 1) (KCP-1) (P53-induced protein PIGPC1) (Transmembrane protein THW). None. GO (18). -
Unknome v3
https://unknome.mrc-lmb.cam.ac.uk/cluster_details/UKP07752/6/1intrinsic apoptotic signaling pathway by p53 class mediator. ... 1) (KCP-1) (P53-induced protein PIGPC1) (Transmembrane protein THW). None. GO (18).
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