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Atomic advance for cryo-EM - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/atomic-advance-for-cryo-em/21 Oct 2020: Nature doi:10.1038/s41586-020-2829-0. Nature News and Views: Cryo-electron microscopy reaches atomic resolution. ... Nature News article:Primary Sidebar. Search. Search this website. 2024 MRC Laboratory of Molecular Biology,. -
Epsin1 tubulation and membrane bending
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/epsin/EM/index.html27 Sep 2007: and McMahon, H.T. (2002) Curvature of clathrin-coated pits driven by epsin. ... see also News and Views and highlights in Nature Cell Biology, Nature reviews in molecular cell biology, and a mini review in Cell (Cell October 18, 2002: 111 (2):143-146). -
Creating an entire bacterial genome with a compressed genetic code -…
https://www2.mrc-lmb.cam.ac.uk/creating-an-entire-bacterial-genome-with-a-compressed-genetic-code/16 May 2019: AGT) and every instance of the stop codon TAG was replaced with its synonym TAA. ... Nature News and Views:Primary Sidebar. Search. Search this website. 2024 MRC Laboratory of Molecular Biology,. -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/4413
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/4413The actin ‘roads’ are built by three specialized proteins, Formin-2, Spire1 and Spire2, that assemble actin filaments from the vesicle surface. ... n. This work was supported by a Framework Programme-7 EU Grant, and the Medical Research Council. -
news and views NATURE CELL BIOLOGY VOL 4 OCTOBER ...
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/ncb1002-e229.pdf23 Sep 2002: news and views. NATURE CELL BIOLOGY VOL 4 OCTOBER 2002 www.nature.com/naturecellbiology E229. ... How these changesare achieved and contribute to vesicle budding is an area ofintense interest. -
AP2 Adaptors Adaptor Home Page Appendage Domains CCV Assembly ...
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/epsin/epsin.html26 Sep 2011: and McMahon, H.T. (2002) Curvature of clathrin-coated pits driven by epsin. ... see also News and Views and highlights in Nature Cell Biology, Nature reviews in molecular cell biology, and a mini review in Cell (Cell October 18, 2002: 111 -
Earlier McMahon Publications
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/oldpaper.html26 Sep 2011: Nature 364, 346-349. (see also News and Views). Link, E., McMahon, H., Fischer von Mollard, G., Yamasaki, S., Niemann, H., Südhof, T.C. ... Nature 365, 163-166. (see also News and Views). McMahon, H.T. and Nicholls, D.G. -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/9253
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/9253To prevent errors in mitosis cells employ checkpoints that monitor and coordinate the correct order of events. ... Conformational variability of the complex allows for UbcH10 association, and they show from a structure of APC/C. -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/13411
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/13411{"id":13411,"date":"2018-12-13T09:40:23","date_gmt":"2018-12-13T09:40:23","guid":{"rendered":"https://www2.mrc-lmb.cam.ac.uk/?p=13411"},"modified":"2018-12-13T09:40:23","modified_gmt":"2018-12-13T09:40:23","slug":"catching-enzymes-in-the-act-of-makin -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/17528
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/17528{"id":17528,"date":"2020-03-04T16:14:53","date_gmt":"2020-03-04T16:14:53","guid":{"rendered":"https://www2.mrc-lmb.cam.ac.uk/?p=17528"},"modified":"2020-03-12T09:20:13","modified_gmt":"2020-03-12T09:20:13","slug":"how-alcohol-derived-dna-damage-is-fi -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/7823
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/7823Each person lived in the laboratory for 49 days (without a clock, or any knowledge of external night and day). ... Melatonin is the main sleep hormone and is released from the pineal gland at night to make you feel sleepy. -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/21899
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/21899 -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/13522
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/13522 -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/19278
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/19278{"id":19278,"date":"2020-10-21T16:32:12","date_gmt":"2020-10-21T15:32:12","guid":{"rendered":"https://www2.mrc-lmb.cam.ac.uk/?p=19278"},"modified":"2020-11-03T14:39:08","modified_gmt":"2020-11-03T14:39:08","slug":"atomic-advance-for-cryo-em","status" -
ENTH domain: A conserved N-terminal domain which in epsin1, 2 and 3…
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/epsin/Structure.html26 Sep 2011: The first picture shows 2 different views of the ENTH domain with a space filled PtdIns(4,5)P. ... see also News and Views and highlights in Nature Cell Biology, Nature reviews in molecular cell biology, and a mini review in Cell (Cell October 18, 2002: -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/14750
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/14750{"id":14750,"date":"2019-05-16T10:04:47","date_gmt":"2019-05-16T09:04:47","guid":{"rendered":"https://www2.mrc-lmb.cam.ac.uk/?p=14750"},"modified":"2019-07-05T10:06:25","modified_gmt":"2019-07-05T09:06:25","slug":"creating-an-entire-bacterial-genome- -
McMahon Group publications
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/papers.html20 Mar 2023: PMID: 20150444 (pdf including supplementary material and figures) (CNCR news) (Faculty of 1000 Exceptional rating). ... 584, 1830-1839. [Epub ahead of print 16Oct 2009] PMID: 19836393 (Ahead of the curve A Nature News and Views feature that highlights -
How alcohol-derived DNA damage is fixed - MRC Laboratory of Molecular …
https://www2.mrc-lmb.cam.ac.uk/how-alcohol-derived-dna-damage-is-fixed/4 Mar 2020: Alcohol consumption can indirectly cause damage to our DNA and elevate cancer risk. ... Nature (Epub ahead of print). Nature News and Views:Primary Sidebar. Search. Search this website. -
New intracellular transport system discovered. - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/new-intracellular-transport-system-discovered/10 Oct 2011: This work was supported by a Framework Programme-7 EU Grant, and the Medical Research Council. ... These cookies (and any others in use) are detailed in our Privacy and Cookies Policy and are integral to our website. -
Protein labeling and imaging
https://www2.mrc-lmb.cam.ac.uk/ccsb/research/protein-labeling/Conformationally strained trans-cyclooctene with improved stability and excellent reactivity in tetrazine ligation. ... Lang, S. Wallace, R. A. Mehl, J. W. Chin. [Featured in News & Views Nature Chem. -
Catching enzymes in the act of making an antibiotic - MRC Laboratory…
https://www2.mrc-lmb.cam.ac.uk/catching-enzymes-in-the-act-of-making-an-antibiotic/13 Dec 2018: key acyl-enzyme intermediates in the synthesis of valinomycin, a compound with antibiotic and anti-tumour properties. ... Nature News and Views:Primary Sidebar. Search. Search this website. 2024 MRC Laboratory of Molecular Biology,. -
Primitive genetic alphabet based on RNA and DNA - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/primitive-genetic-alphabet-based-on-rna-and-dna/3 Jun 2020: Primitive genetic alphabet based on RNA and DNA. Published on. 3 June, 2020. ... News and Views:Primary Sidebar. Search. Search this website. 2024 MRC Laboratory of Molecular Biology,. -
Publications
https://www2.mrc-lmb.cam.ac.uk/groups/rh15/Publications.html14 Apr 2021: Henderson, R. Nature, News and Views 318, 598-599 (1985). Structure of a bacterial photosynthetic reaction centre. ... Henderson, R. Nature, News and Views, 287, 490 (1980). Crystallizing membrane proteins. -
Public Engagement - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/news-events/public-engagement/feed/8 Jul 2024: https://www2.mrc-lmb.cam.ac.uk/news-events/public-engagement/ One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the ... www2.mrc-lmb.cam.ac.uk/group-leaders/a-to-g/radu-aricescu/ -
Molecular basis of APC/C regulation by the spindle assembly…
https://www2.mrc-lmb.cam.ac.uk/molecular-basis-apcc-regulation-spindle-assembly-checkpoint/11 Aug 2016: To prevent errors in mitosis cells employ checkpoints that monitor and coordinate the correct order of events. ... Conformational variability of the complex allows for UbcH10 association, and they show from a structure of APC/C. -
Effects of caffeine on the human circadian clock - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/effects-of-caffeine-on-the-human-circadian-clock/17 Sep 2015: Each person lived in the laboratory for 49 days (without a clock, or any knowledge of external night and day). ... Melatonin is the main sleep hormone and is released from the pineal gland at night to make you feel sleepy. -
All publications
https://www2.mrc-lmb.cam.ac.uk/ccsb/publications/all-publications-2/Lang, S. Wallace, R. A. Mehl, J. W. Chin. [Featured in News & Views Nature Chem. ... K. Wang, H. Neumann, J. W. Chin. [News & Views Nature Biotech. -
HARVEY T McMAHON
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/people/CV2006d.html25 Jun 2007: Nature article 419, 361-366. (see also News and Views and highlights in Nature Cell Biology, Nature reviews in molecular cell biology, and a mini review in Cell). ... Nature 365, 163-166. (see also News and Views). McMahon, H.T. and Nicholls, D.G. -
Electron Cryo-microscopy - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/news-events/public-engagement/cryo-electron-microscopy/feed/8 Jul 2024: https://www2.mrc-lmb.cam.ac.uk/news-events/public-engagement/cryo-electron-microscopy/ One of the world's leading research institutes, our scientists are working to advance understanding of biological ... www2.mrc-lmb.cam.ac.uk/group-leaders/a-to-g/radu-a -
Structural breakthrough in study of aggregated TDP-43 protein in…
https://www2.mrc-lmb.cam.ac.uk/structural-breakthrough-in-study-of-aggregated-tdp-43-protein-in-brains-of-als-and-ftd-sufferers/8 Dec 2021: Structural breakthrough in study of aggregated TDP-43 protein in brains of ALS and FTD sufferers. ... This research relied on individuals (and their families) donating their brains to research. -
Structures of the human GABAA receptor reveal how it functions and…
https://www2.mrc-lmb.cam.ac.uk/structures-of-the-human-gabaa-receptor-reveal-how-it-functions-and-could-help-improve-key-drugs/3 Jan 2019: A. and GABA. B. , with GABA. A. receptors mediating millisecond-fast neurotransmission and GABA. ... and Aricescu, AR. Nature 565(7740): 454-459. Nature News and Views:Primary Sidebar. -
emulator as well as a solid understanding of its ...
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Papers/Traub&Wendland2010.pdf1 Jun 2010: Proteins and lipids are shuttled between membrane-bounded cellular compartments by vesicular carriers. ... Within a minute, it gently curves, invaginates deeply and constricts at the base. -
Jason William Chin Page 1 of 18 MRC Laboratory ...
https://www2.mrc-lmb.cam.ac.uk/ccsb/wp-content/uploads/2024/01/Chin-cv-26012024.pdf29 Jan 2024: 25: 770-777. [News & Views Nature Biotech. 2007. 25: 745-746.] (29) Expanding Nucleic Acid Function in vitro and in vivo. ... 2006. 2: 254-258. [News & Views, Nature Chem. Biol. 2006. 2: 231-232].
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