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Dr Jason Sang | Yusuf Hamied Department of Chemistry
https://www.ch.cam.ac.uk/person/cs78313 Jul 2024: Nature Neuroscience. (2019). 23,. 21. (doi:Direct observation of prion protein oligomer formation reveals an aggregation mechanism with multiple conformationally distinct species. -
Publications | Centre for Experimental Biophysical Chemistry
https://www.ch.cam.ac.uk/biophyschem/publications?page=1713 Jul 2024: Nature Communications. (2019). 10,. 5610. (doi:α-Synuclein strains target distinct brain regions and cell types. ... Nature Neuroscience. (2019). 23,. 21. (doi:Trodusquemine enhances Aβ42 aggregation but suppresses its toxicity by displacing oligomers -
Publications | Centre for Experimental Biophysical Chemistry
https://www.ch.cam.ac.uk/biophyschem/publications?page=513 Jul 2024: Nature Neuroscience. (2022). 25,. 1582. (doi: 10.1038/s41593-022-01206-2). Characterization of full-length p53 aggregates and their kinetics of formation. ... Nature Structural and Molecular Biology. (2022). 29,. 831. (doi: 10.1038/s41594-022-00814-7). -
Researchers identify a tau homeostasis signature that underlies…
https://www.ch.cam.ac.uk/news/researchers-identify-tau-homeostasis-signature-underlies-alzheimer%E2%80%99s-disease13 Jul 2024: In a paper published in Nature Neuroscience, the scientists explain how they wanted to investigate why aberrant protein aggregates form in some cells but not others. ... A tau homeostasis signature is linked with the cellular and regional vulnerability -
Researchers identify a tau homeostasis signature that underlies…
https://www.ch.cam.ac.uk/chemistry-of-health/researchers-identify-tau-homeostasis-signature-underlies-alzheimer%E2%80%99s-disease13 Jul 2024: In a paper published in Nature Neuroscience, the scientists explain how they wanted to investigate why aberrant protein aggregates form in some cells but not others. ... A tau homeostasis signature is linked with the cellular and regional vulnerability
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