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1 - 6 of 6 search results for `cells in a p53`

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  2. p53 impairs CRISPR/Cas9 in healthy cells | Department of Biochemistry

    https://www.bioc.cam.ac.uk/news/archive/2018/p53-impairs-crispr-cas9-in-healthy-cells
    23 Jul 2024: These results suggest that CRISPR/Cas9 selects against cells with a functional p53 pathway, which can explain the higher efficiency of CRISPR/Cas9 in tumour cell lines where the p53 DNA ... A delicate balance is required, however, as p53 inhibition can

  3. Autophagy-mediated apoptosis eliminates chromosomally abnormal cells…

    https://www.pdn.cam.ac.uk/news/autophagy-mediated-apoptosis-eliminates-chromosomally-abnormal-cells-from-the-mouse-epiblast
    23 Jul 2024: This stress in turn activates a catabolic process, known as autophagy that leads to the death of the abnormal cells in a p53-dependent process. ... Future studies in higher mammalian species are however required to reveal if p53-dependent autophagy and

  4. Autophagy-mediated apoptosis eliminates chromosomally abnormal cells…

    https://www.trophoblast.cam.ac.uk/news/autophagy-mediated-apoptosis-eliminates-chromosomally-abnormal-cells-from-the-mouse-epiblast
    23 Jul 2024: This stress in turn activates a catabolic process, known as autophagy that leads to the death of the abnormal cells in a p53-dependent process. ... Future studies in higher mammalian species are however required to reveal if p53-dependent autophagy and

  5. Professor Bertie Göttgens - Department of Haematology

    https://www.haem.cam.ac.uk/staff/senior-staff/professor-bertie-gottgens/
    23 Feb 2024: Genotoxic aldehyde stress prematurely ages hematopoietic stem cells in a p53-driven manner” Mol Cell. ... Watson JK, Rulands S, Wilkinson AC, Wuidart A, Ousset M, Van Keymeulen A, Göttgens B, Blanpain C, Simons BD, Rawlins EL, “Clonal Dynamics

  6. https://www.phar.cam.ac.uk/taxonomy/term/5/feed

    https://www.phar.cam.ac.uk/taxonomy/term/5/feed
    23 Jul 2024: and Howarth, M., 2021. <i>Overcoming Symmetry Mismatch in Vaccine Nanoassembly through Spontaneous Amidation. ... H-J., Andersson, A-MC., Barrett, JR., Bowden, TA., Draper, SJ., Townsend, AR.

  7. Autophagy-mediated apoptosis eliminates chromosomally abnormal cells…

    https://www.trophoblast.cam.ac.uk/news/autophagy-mediated-apoptosis-eliminates-chromosomally-abnormal-cells-from-the-mouse-epiblast
    18 Jul 2024: This stress in turn activates a catabolic process, known as autophagy that leads to the death of the abnormal cells in a p53-dependent process. ... Future studies in higher mammalian species are however required to reveal if p53-dependent autophagy and

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