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Understanding the roles of autophagy and related pathways in…
https://www.ubs.admin.cam.ac.uk/system/files/public/understanding_the_roles_of_autophagy_and_related_pathways_in_proteinopathies_non-technical_summary_redacted.pdf30 Apr 2024: With increased population lifespan, the incidence of people experiencing these devastating disorders will continue to rise. ... Our work has the potential to impact millions of people worldwide both at the social and economic levels. -
Gonville & Caius College
https://www.cai.cam.ac.uk/sites/default/files/2024-05/Development%20Officer%20May24_JD.pdf2 May 2024: to deal with a wide range of people with empathy and. -
Proteotoxicity in development and ageing (non-technical…
https://www.ubs.admin.cam.ac.uk/system/files/public/proteotoxicity_in_development_and_ageing_non-technical_summary_redacted.pdf30 Apr 2024: Downloaded: 9:21pm, 25 Apr 2024 Page 3 of 10. Dementias are the biggest health challenge of our generation; one in three people born today will develop the disease. ... With one million people in the UK predicted to have dementia by 2025 and the current -
Genes and environment at the interface of inflammation, immunity and…
https://www.ubs.admin.cam.ac.uk/system/files/public/genes_and_environment_at_the_interface_of_inflammation_immunity_and_metabolism_non-technical_summa_redacted.pdf30 Apr 2024: Where possible in our design we blind people to genotype/treatment groups with different people doing infections or analysis. ... We will discuss any advances with the relevant people at our establishment and implement them accordingly. -
Investigating the niche of mucosal parasitic nematodes and their…
https://www.ubs.admin.cam.ac.uk/system/files/public/investigating_the_niche_of_mucosal_parasitic_nematodes_and_their_interactions_with_their_hosts_non_redacted.pdf30 Apr 2024: Whipworms infect 500 million people worldwide, particularly affecting children 5-15 years of age. ... Hookworms infect 450 million people around the globe, and can cause iron deficiency anaemia, especially in high-risk populations (children and women of -
Interaction between the immune system and tumours (non-technical…
https://www.ubs.admin.cam.ac.uk/system/files/public/interaction_between_the_immune_system_and_tumours_non-technical_summary_redacted.pdf30 Apr 2024: Why is it important to undertake this work? It is now predicted that 1 in 2 people will develop cancer in their lifetime and despite advances with new treatments they do ... We subscribe to the NC3Rs email updates and also receive regular updates from -
Determining mechanisms of tumour development and relapse following…
https://www.ubs.admin.cam.ac.uk/system/files/public/determining_mechanisms_of_tumour_development_and_relapse_following_treatment_non-technical_summary_redacted.pdf29 Apr 2024: Furthermore, to determine whether inhibition of the activities of these proteins will be effective in the treatment of people with cancer. ... Downloaded: 9:12pm, 25 Apr 2024 Page 6 of 11. Some mice can experience weight loss due to the effects of the -
Neurobehavioural Mechanisms Underlying Mood, Impulsive and Compulsive …
https://www.ubs.admin.cam.ac.uk/system/files/public/neurobehavioural_mechanisms_underlying_mood_impulsive_and_compulsive_mental_health_disorders_non-t_redacted.pdf30 Apr 2024: benefit people living with mental health disorders through the development of new treatments. ... In the longer term, understanding the risk factors that predict whether individuals are more vulnerable to developing mental health disorders may allow -
Discovery and development of treatments for immunological diseases
https://www.ubs.admin.cam.ac.uk/system/files/public/discovery_and_development_of_treatments_for_immunological_diseases_non-technical_summary_redacted.pdf29 Apr 2024: Why is it important to undertake this work? Despite decades of research, millions of people live with serious immune mediated disease such as colitis, arthritis, systemic lupus erythematosus (SLE) and atopic ... dermatitis. For example rheumatoid -
Provision of an outsourced drug development platform for the…
https://www.ubs.admin.cam.ac.uk/system/files/public/provision_of_an_outsourced_drug_development_platform_for_the_treatment_of_bleeding_disorders_non-te_redacted.pdf30 Apr 2024: Finding treatments for all aspects of patient care therefore is crucial to improve outcomes for people affected. ... All clients that we work with are developing test agents which will hopefully contribute to helping people with various bleeding disorders
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