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  2. Many cases of dementia may arise from non-inherited DNA ‘spelling…

    https://www.ats.cam.ac.uk/news/many-cases-dementia-may-arise-non-inherited-dna-spelling-mistakes
    1 Jun 2024: Only around one in twenty patients has a family history, where genetic variants inherited from one or both parents contributes to disease risk. ... These spelling errors arise in our DNA as cells divide, and could explain why so many people develop

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