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PhD & postdoc Seminars | Wellcome-MRC Cambridge Stem Cell…
https://www.stemcells.cam.ac.uk/events/phd-postdoc-seminars23 Feb 2024: Stephen Loughran, postdoc, Green lab. "JAK2 phosphorylates the RNA binding protein HNRNPA1 to repress endogenous retrovirus expression and protect haematopoiesis". -
Churchill College Alumnus awarded Humboldt Prize for World-leading…
https://www.chu.cam.ac.uk/news/news-and-events/churchill-college-alumnus-awarded-humboldt-prize-for-world-leading-evolutionary-genetics-research/
26 Mar 2024:
I was wondering how to examine this and noticed something odd: several hundred copies of a fairly new (to our genome) endogenous retrovirus (ERV) were all active in early human embryos
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Publications | Coleman Laboratory
https://colemanlab.brc.cam.ac.uk/publications23 Feb 2024: 2020) Human endogenous retrovirus HERV-K(HML-2) RNA causes neurodegeneration through Toll-like receptors. ... 2010) Endogenous Nmnat2 is an essential survival factor for maintenance of healthy axons. Results that match 1 of 2 words
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Curriculum Vitae
www.statslab.cam.ac.uk/~qz280/files/cv.pdf20 Mar 2024: S. Small, “ivmodel: An R package for inference andsensitivity analysis of instrumental variables models with one endogenous variable,” Ob-servational Studies, vol. -
Filament structure and subcellular organization of the bacterial…
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/Liu_PNAS_crescentin_2024.pdf28 Apr 2024: This yielded protein levels of CreS similar to endogenous levels in wt strain CB15N (SI Appendix, Fig. ... Subcellular Organization of CreS Filaments. The ultrastructure of endogenous CreS assemblies at normal levels in C. -
LMB Fellows - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/group-leaders/lmb-fellows/
23 Apr 2024:
His application of forward-genetic screens discovered the Human Silencing Hub ‘HUSH’, the critical transcriptional epigenetic repressor complex for silencing both newly integrated retroviruses and mobile endogenous retrotransposons.
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Mouse developmental genetics to study neurodevelopment and disease…
https://www.ubs.admin.cam.ac.uk/system/files/public/mouse_developmental_genetics_to_study_neurodevelopment_and_disease_non-technical_summary_redacted.pdf30 Apr 2024: Importantly, in the long term, this project will provide a springboard to utilize endogenous neural stem cells as therapeutic entry points for regenerative medicine in the brain. -
Dr Fotios Sampaziotis | Wellcome-MRC Cambridge Stem Cell Institute
https://www.stemcells.cam.ac.uk/people/pi/sampaziotis23 Feb 2024: endogenous regeneration as a therapeutic strategy to repair duct damage. ... We are trying to understand why this mechanism fails in disease and identify therapeutics modifying the cells’ microenvironment to promote endogenous regeneration. -
Professor Paul Lehner | Wellcome-MRC Cambridge Stem Cell Institute
https://www.stemcells.cam.ac.uk/people/affiliates/lehner23 Feb 2024: Remarkably HUSH also silences endogenous mobile retrotransposons like LINE-1 elements, which make up 17% of our genome. -
https://www.psychiatry.cam.ac.uk/blog/tag/valerie-voon/feed/
https://www.psychiatry.cam.ac.uk/blog/tag/valerie-voon/feed/16 Feb 2024: This drug inhibits activity of the endogenous opioid system, which, along with dopamine, contributes to the development and maintenance of addiction.
26 Mar 2024:
I was wondering how to examine this and noticed something odd: several hundred copies of a fairly new (to our genome) endogenous retrovirus (ERV) were all active in early human embryos
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