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Cambridge Clinical Multiple Sclerosis Research
https://www-neurosciences.medschl.cam.ac.uk/cambridge-clinical-ms-research/23 Feb 2024: Investigating natural remyelination in people with MS. Doing clinical trials to identify drugs which promote endogenous remyelination in people with MS. -
vsvg_pseudtyped_retrovirus_101209_0clip_image004.png | Ron Lab
https://ron.cimr.cam.ac.uk/file/vsvgpseudtypedretrovirus1012090clipimage004png23 Feb 2024: Search site. Ron Lab. vsvg_pseudtyped_retrovirus_101209_0clip_image004.png. 2024 University of Cambridge. -
Dr Wei Li | Cambridge Cardiovascular
https://www.cardiovascular.cam.ac.uk/directory/wli23 Feb 2024: We also show that loss of endogenous BMP9 leads to lung vascular leak in vivo, and have developed BMP9 variants that maintain endothelial protective function but lack the bone-forming activity. -
Research
https://www.med.cam.ac.uk/li/research/23 Feb 2024: We also show that loss of endogenous BMP9 leads to lung vascular leak in vivo, and have developed BMP9 variants that maintain endothelial protective function but lack the bone-forming activity. -
Publications - Professor Morrell's Group
https://www.med.cam.ac.uk/morrell/publications/23 Feb 2024: Elabela/Toddler is an Endogenous Agonist of the Apelin APJ receptor in the adult cardiovascular system, and exogenous administration of the peptide compensates for the downregulation of its expression in pulmonary -
Dr Janet Maguire | Cambridge Cardiovascular
https://www.cardiovascular.cam.ac.uk/directory/jmaguire23 Feb 2024: Pyr. 1. ]apelin-13. (1-12). is a biologically active ACE2 metabolite of the endogenous cardiovascular peptide [Pyr. ... Elabela/Toddler is an endogenous agonist of the apelin APJ receptor in the adult cardiovascular system, and exogenous administration -
Robyn Macrae | Cambridge Cardiovascular
https://www.cardiovascular.cam.ac.uk/directory/robyn-macrae23 Feb 2024: Title: The apelin signalling system is composed of the G-protein coupled apelin receptor and its two endogenous peptide ligands, apelin and Elabela/Toddler (ELA). ... Structure and pharmacology of the apelin receptor with a recommendation that -
Dr Andrew Sage | Cambridge Cardiovascular
https://www.cardiovascular.cam.ac.uk/directory/asage23 Feb 2024: Recently, our lab defined the direct overall contribution of endogenous antibodies to atherosclerosis in a fully immunocompetent model. -
Professor Robert Glen | Cambridge Cardiovascular
https://www.cardiovascular.cam.ac.uk/directory/rglen23 Feb 2024: FAst MEtabolizer (FAME): A rapid and accurate predictor of sites of metabolism in multiple species by endogenous enzymes. -
Professor Guy Brown | Cambridge Cardiovascular
https://www.cardiovascular.cam.ac.uk/directory/gbrown23 Feb 2024: Galectin-3, a novel endogenous TREM2 ligand, detrimentally regulates inflammatory response in Alzheimer's disease. -
Professor Colin Taylor | Cambridge Cardiovascular
https://www.cardiovascular.cam.ac.uk/directory/ctaylor23 Feb 2024: Endogenous signalling pathways and caged-IP. 3. evoke Ca. 2+. puffs at the same abundant immobile intracellular sites. -
https://www.medschl.cam.ac.uk/tag/endocrinology/feed/
https://www.medschl.cam.ac.uk/tag/endocrinology/feed/23 Feb 2024: dosing schedules, we have been able to closely replicate the changes in endogenous cortisol levels observed in traders during periods of increased market volatility,” says Dr Mark Gurnell from the Institute -
The power of hormones on the world’s trading floors - School of…
https://www.medschl.cam.ac.uk/power-hormones-worlds-trading-floors/23 Feb 2024: By using personalised dosing schedules, we have been able to closely replicate the changes in endogenous cortisol levels observed in traders during periods of increased market volatility,” says Dr Mark Gurnell -
Professor Paul Lehner | Wellcome-MRC Cambridge Stem Cell Institute
https://www.stemcells.cam.ac.uk/people/affiliates/lehner23 Feb 2024: Remarkably HUSH also silences endogenous mobile retrotransposons like LINE-1 elements, which make up 17% of our genome. -
Professor Jon Yewdell | Cambridge Immunology Network
https://www.immunology.cam.ac.uk/Networkdirectory/yewdell23 Feb 2024: 2012). MHC class I antigen processing distinguishes endogenous antigens based on their translation from cellular vs. ... 2012). Endogenous viral antigen processing generates peptide-specific MHC class I cell-surface clusters. -
Publications - Clinical Gerontology
https://www.phpc.cam.ac.uk/gerontology/publications/23 Feb 2024: Endogenous sex hormones and endometrial cancer risk in women in the European Prospective Investigation into Cancer and Nutrition ( EPIC ). Endocr Relat Cancer. 2008 Jun;15(2):485-497. Rohrmann S, Linseisen ... Endogenous androgens and risk of epithelial -
Joshua Bernstock | Cambridge Immunology Network
https://www.immunology.cam.ac.uk/Networkdirectory/bernstock23 Feb 2024: Endogenous NPCs subsequently migrate toward the ischemic lesion where they promote tissue remodeling and neural repair. ... restorative responses initially executed by the endogenous NPC population. We claim that understanding these immunomodulatory -
LMB Fellows - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/group-leaders/lmb-fellows/23 Apr 2024: His application of forward-genetic screens discovered the Human Silencing Hub ‘HUSH’, the critical transcriptional epigenetic repressor complex for silencing both newly integrated retroviruses and mobile endogenous retrotransposons. -
Dr Nicholas Matheson | Cambridge Immunology Network
https://www.immunology.cam.ac.uk/Networkdirectory/njm25%40cam.ac.uk23 Feb 2024: host-pathogen interaction. proteomics. retrovirus. immunobiology. SILAC. metabolism. Contact us. Cambridge Immunology Network Coordinator. -
Professor Jonathan Luke Heeney | Cambridge Immunology Network
https://www.immunology.cam.ac.uk/Networkdirectory/heeney23 Feb 2024: virology. innate immunity. retrovirus. Immunosenescence. Calcivirus RNA viruses. Immune-ageing. Contact us.
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