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  2. doi:10.1016/j.molcel.2008.05.027

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/FtsK%20MolCell%202008%20Lowe.pdf
    16 Aug 2008: In. the overlapping regions, Watson-Crick base pairs form be-. tween the different strands, though the DNA used is blunt-.
  3. Photographs - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/about-lmb/archive/photographs/
    Thumbnail for Photographs - MRC Laboratory of Molecular Biology 21 Jul 2023: Photographs The LMB has an extensive collection of photographs and images, a selection of which can be viewed here by either browsing the collection or
  4. doi:10.1016/j.neuron.2005.05.004

    https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Jockusch_Neuron2005.pdf
    17 Jun 2005: Neuron 17, 1241–1249. Miele, A.E., Watson, P.J., Evans, P.R., Traub, L.M., and Owen, D.J.(2004).
  5. DNA 60th Anniversary celebrated at Cambridge - MRC Laboratory of…

    https://www2.mrc-lmb.cam.ac.uk/wp-json/oembed/1.0/embed?url=https%3A%2F%2Fwww2.mrc-lmb.cam.ac.uk%2Fdna-60th-anniversary-celebrated-at-cambridge%2F&format=xml
    25th April 1953, Francis Crick and Jim Watson published their groundbreaking paper in Nature, in which they revealed to the world the double.
  6. LMB Nobel Facts - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/achievements/lmb-nobel-prizes/nobel-facts/
    Thumbnail for LMB Nobel Facts - MRC Laboratory of Molecular Biology 21 Jul 2023: 1962 - Francis Crick & Jim Watson (Physiology or Medicine). 1958 - Fred Sanger (Chemistry). ... In 1962, the LMB was awarded 2 separate Nobel Prizes: Francis Crick and Jim Watson (Physiology or Medicine), and Max Perutz and John Kendrew (Chemistry).
  7. Tyrosine Residues in Phospholipase C�2 Essential for the…

    https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/11606584.pdf
    20 Apr 2002: Tyrosine Residues in Phospholipase C2 Essential for the EnzymeFunction in B-cell Signaling. Received for publication, August 8, 2001, and in revised form, October 9, 2001Published, JBC Papers in Press, October 17, 2001, DOI 10.1074/jbc.M107577200.
  8. PII: S1097-2765(03)00356-3

    https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/gripdomain.pdf
    27 Oct 2003: genes. Proc. Natl. Acad. Sci. USA90, 8952–8956.Analytical UltracentrifugationCollins, B.M., Watson, P.J., and Owen, D.J.
  9. Interactive Tools forCryo-EM Map Fitting Paul EmsleyMRC Laboratory of …

    https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/files/presentations/coot-cryoEM-2018-June-PSI.pdf
    19 Jun 2018: Base-stacking restraints:(parallel plane restraints). LIBG Restraints. (Watson Crick and) Wobble, Reverse Wobble.
  10. Evolving nature of the AP2 a-appendage hubduring clathrin-coated…

    https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/AP2Hub_EMBO2004/AP2Praefcke2004.pdf
    23 Nov 2004: Evolving nature of the AP2 a-appendage hubduring clathrin-coated vesicle endocytosis. Gerrit JK Praefcke1,2, Marijn GJ Ford1,Eva M Schmid, Lene E Olesen,Jennifer L Gallop, Sew-Yeu Peak-Chew,Yvonne Vallis, M Madan Babu,Ian G Mills3 and Harvey T
  11. Coot Tools for Cryo-EM Paul EmsleyMRC Laboratory of Molecular ...

    https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/files/presentations/coot-cryoEM-2018-Aug-Stockholm.pdf
    15 Aug 2018: Base-stacking restraints:(parallel plane restraints). LIBG Restraints. (Watson Crick and) Wobble, Reverse Wobble.
  12. Supplemental Materials Supp MethodsSupp Fig. 1 Sequence conservation…

    https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/AP2Hub_EMBO2004/AP2Praefcke2004Sup.pdf
    23 Nov 2004: J Biol Chem278, 46772-46781. Miele, A. E., Watson, P. J., Evans, P.
  13. “The LMB provides an unsurpassed environment for both new ...

    https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/www2.mrc-lmb.cam.ac.uk/?wpdmdl=18852
    18 Jan 2021: Francis Crick and James Watson, 1962 - discovery of the structure of DNA.
  14. Expression, purifica0on, characteriza0on, and crystalliza0on So how…

    https://www2.mrc-lmb.cam.ac.uk/download/03-protein-expression-crystallization-and-mutagenesis-meindert-lamers/?wpdmdl=18793&refresh=6649f7ad76e8c1716123565
    2 May 2013: Watson & Crick). Recommended reading: Liga0on Independent Cloning Aslanidis C, de Jong PJ.
  15. https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/32

    https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/32
  16. Scientific Models - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/about-lmb/archive/scientific-models/
    Thumbnail for Scientific Models - MRC Laboratory of Molecular Biology 21 Jul 2023: Base plate from the Watson and Crick 1953 model. Signed by Francis Crick and Jim Watson. ... A year later I was able to get Jim Watson’s signature when he stopped by the LMB on a visit.’ Arthur Arnone, 28 October 2003.
  17. Functional Depletion of Mahogunin by Cytosolically Exposed Prion…

    https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/59_Chakrabarti_O_Cell_2009.pdf
    13 Jun 2009: Functional Depletion of Mahoguninby Cytosolically Exposed Prion ProteinContributes to NeurodegenerationOishee Chakrabarti1 and Ramanujan S. Hegde1,1Cell Biology and Metabolism Program, National Institute of Child Health and Human Development,
  18. coot-user-manual.dvi

    https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/web/docs/coot-user-manual.pdf
    28 Sep 2012: 16311.85.2 watson-crick-pair. 16411.85.3 watson-crick-pair-for-residue-range. 164. xix. 11.86 Sequence (Assignment). 16411.86.1 print-sequence-chain.
  19. Publications

    https://www2.mrc-lmb.cam.ac.uk/groups/jes/publications.html
    17 Sep 2020: Ho, T.L.F., Guilbaud, G., Blow, J.J., Sale, J.E. and Watson, C.J.
  20. New method to untangle the contribution of signalling pathways…

    https://www2.mrc-lmb.cam.ac.uk/new-method-to-untangle-the-contribution-of-signalling-pathways-involved-in-asymmetric-cell-division/
    Thumbnail for New method to untangle the contribution of signalling pathways involved in asymmetric cell division - MRC Laboratory of Molecular Biology 28 Sep 2023: In this study, co-led by Joseph Watson and Lara Krüger, the team developed an assay which allows the contribution of each pathway involved in the process to be dissected. ... Watson, JL., Krüger, LK., Ben-Sasson, AJ., Bittleston, A., Shahbazi, M.,
  21. Coot Scripting Interface: File Members

    https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/docs/html/globals_0x77.html
    24 Aug 2021: watson_crick_pair() : c-interface.h. ... watson_crick_pair_for_residue_range() : c-interface.h.
  22. https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/1985

    https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/1985
  23. Browse the photo archive - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/about-lmb/archive/photographs/browse-all/
    Thumbnail for Browse the photo archive - MRC Laboratory of Molecular Biology 31 Mar 2021: Reproduction of Watson & Crick DNA Model.
  24. Recordings - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/about-lmb/archive/recordings/
    Thumbnail for Recordings - MRC Laboratory of Molecular Biology 21 Jul 2023: Isaac Asimov introduces James Watson and Francis Crick in the story of the structure of DNA, 8 July 1974. ... Discovering the double helix. James Watson talks about the discovery of the double helix in a lecture at Cold Spring Harbor Laboratory, November
  25. Kiyoshi Nagai (1949 - 2019) - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/kiyoshi-nagai-1949-2019/
    Thumbnail for Kiyoshi Nagai (1949 - 2019) - MRC Laboratory of Molecular Biology 2 Oct 2019: In this last complex, the detailed description of non-Watson-Crick base pairs between the 3’ splice site AG dinucleotide and both the branch-point adenosine and the 5’ splice site
  26. Twinning and other pathologies Andrey Lebedev CCP4 OD-­‐structures…

    https://www2.mrc-lmb.cam.ac.uk/download/twinningaandaotherapathologiesa-andreyalebedeva-a/?wpdmdl=18788&refresh=6649f7ae1dfb71716123566
    11 Jun 2013: a. b. Human macrophage receptor CLEC5A for dengue virus Watson, A.
  27. Expression, purifica0on, characteriza0on, and crystalliza0on So how…

    https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/courses/lmb_crystallography_course_2013/lectures/20130430_Cryst_course.pdf
    2 May 2013: Watson & Crick). Recommended reading: Liga0on Independent Cloning Aslanidis C, de Jong PJ.
  28. https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/20969

    https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/20969
    {"id":20969,"date":"2021-08-06T16:48:14","date_gmt":"2021-08-06T14:48:08","guid":{"rendered":"https://www2.mrc-lmb.cam.ac.uk/?page_id=20969"},"modified":"2021-11-18T14:33:20","modified_gmt":"2021-11-18T14:33:20","slug":"herbert-freddie-gutfreund","st
  29. https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/1968

    https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/1968
    {"id":1968,"date":"2012-07-18T15:55:14","date_gmt":"2012-07-18T14:55:03","guid":{"rendered":"http://www2.mrc-lmb.cam.ac.uk/wordpress/?page_id=1968"},"modified":"2021-05-21T13:29:26","modified_gmt":"2021-05-21T12:29:26","slug":"lmb-alumni-carl-ivar-br
  30. Books - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/about-lmb/archive/books/
    Thumbnail for Books - MRC Laboratory of Molecular Biology 21 Jul 2023: DNA. The Big Idea: Crick, Watson & DNA. Strathern, Paul. London: Arrow Books, 1997. ... The involvement of RNA in the synthesis of nucleic acids’ by James Watson.
  31. History of the LMB - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/about-lmb/history-of-the-lmb/
    Thumbnail for History of the LMB - MRC Laboratory of Molecular Biology 21 Jul 2023: Nobel Prize for Physiology or Medicine: Francis Crick and Jim Watson.
  32. Twinning and other pathologies Andrey Lebedev CCP4 OD-­‐structures…

    https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/courses/lmb_crystallography_course_2013/lectures/pathologies_and_twinning.pdf
    11 Jun 2013: a. b. Human macrophage receptor CLEC5A for dengue virus Watson, A.
  33. https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/21995

    https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/21995
    {"id":21995,"date":"2022-01-05T11:54:57","date_gmt":"2022-01-05T11:54:21","guid":{"rendered":"https://www2.mrc-lmb.cam.ac.uk/?page_id=21995"},"modified":"2022-01-05T12:18:56","modified_gmt":"2022-01-05T12:18:56","slug":"donald-caspar-1927-2021","stat
  34. https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/26

    https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/26
    {"id":26,"date":"2012-06-25T09:58:08","date_gmt":"2012-06-25T09:58:08","guid":{"rendered":"http://www2.mrc-lmb.cam.ac.uk/wordpress/?page_id=26"},"modified":"2023-07-21T12:49:27","modified_gmt":"2023-07-21T11:49:27","slug":"photographs","status":"publ
  35. https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/28892

    https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/28892
    {"id":28892,"date":"2022-12-15T10:50:17","date_gmt":"2022-12-15T10:50:17","guid":{"rendered":"https://www2.mrc-lmb.cam.ac.uk/?p=28892"},"modified":"2022-12-15T10:51:51","modified_gmt":"2022-12-15T10:51:51","slug":"lmb-through-the-years-60-years-of-me
  36. https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/997

    https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/997
    {"id":997,"date":"2012-07-03T09:13:21","date_gmt":"2012-07-03T09:13:21","guid":{"rendered":"http://www2.mrc-lmb.cam.ac.uk/wordpress/?page_id=997"},"modified":"2023-07-21T12:49:21","modified_gmt":"2023-07-21T11:49:21","slug":"fast-facts","status":"pub
  37. Site Map - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/site-map/
    Thumbnail for Site Map - MRC Laboratory of Molecular Biology 21 Feb 2020: One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the molecular level - providing the knowledge needed to solve key problems in human health. Search this website. Site Map.
  38. LMB Alumni List - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/alumni/
    Thumbnail for LMB Alumni List - MRC Laboratory of Molecular Biology 9 May 2024: LMB Alumni List This is an alphabetical listing of past members of the LMB, complete with tenure dates. The list has been compiled by cross-referencing
  39. Michael Fuller (1936 - 2019) - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/michael-fuller-1936-2019/
    Thumbnail for Michael Fuller (1936 - 2019) - MRC Laboratory of Molecular Biology 28 Nov 2019: This was especially apt, as Michael was already working in the Laboratory when Francis Crick and James Watson announced the structure of DNA and unveiled their model, in 1953.
  40. 1982 - Aaron Klug - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/achievements/lmb-nobel-prizes/1982-aaron-klug/
    Thumbnail for 1982 - Aaron Klug - MRC Laboratory of Molecular Biology 21 Jul 2023: 1982 Chemistry Prize - Aaron Klug “for his development of crystallographic electron microscopy and his structural elucidation of biologically important
  41. 1980 - Fred Sanger - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/achievements/lmb-nobel-prizes/1980-fred-sanger/
    Thumbnail for 1980 - Fred Sanger - MRC Laboratory of Molecular Biology 21 Jul 2023: 1980 Chemistry Prize - Fred Sanger “for their contributions concerning the determination of base sequences in nucleic acids”
  42. https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/1018

    https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/1018
    {"id":1018,"date":"2012-07-03T09:31:54","date_gmt":"2012-07-03T09:31:54","guid":{"rendered":"http://www2.mrc-lmb.cam.ac.uk/wordpress/?page_id=1018"},"modified":"2023-07-21T12:49:56","modified_gmt":"2023-07-21T11:49:56","slug":"published-research","st
  43. https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/14

    https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/14
    {"id":14,"date":"2012-06-25T09:56:10","date_gmt":"2012-06-25T09:56:10","guid":{"rendered":"http://www2.mrc-lmb.cam.ac.uk/wordpress/?page_id=14"},"modified":"2023-07-21T12:49:24","modified_gmt":"2023-07-21T11:49:24","slug":"history-of-the-lmb","status
  44. 1997 - John Walker - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/achievements/lmb-nobel-prizes/1997-john-walker/
    Thumbnail for 1997 - John Walker - MRC Laboratory of Molecular Biology 21 Jul 2023: 1997 Chemistry Prize - John Walker “for their elucidation of the enzymatic mechanism underlying the synthesis of adenosine triphosphate (ATP)”
  45. 1958 - Fred Sanger - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/achievements/lmb-nobel-prizes/1958-fred-sanger/
    Thumbnail for 1958 - Fred Sanger - MRC Laboratory of Molecular Biology 21 Jul 2023: 1958 Chemistry Prize - Fred Sanger “for his work on the structure of proteins, especially that of insulin”
  46. 2017 - Richard Henderson - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/achievements/lmb-nobel-prizes/2017-richard-henderson/
    Thumbnail for 2017 - Richard Henderson - MRC Laboratory of Molecular Biology 21 Jul 2023: 2017 Chemistry Prize - Richard Henderson "for developing cryo-electron microscopy for the high-resolution structure determination of biomolecules in
  47. Coot Scripting Interface: c-interface.h File Reference

    https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/docs/html/c-interface_8h.html
    24 Aug 2021: Coot Scripting Interface 7000. c-interface.h File Reference. Coot Scripting Interface - General. Functions. SCM . merge_molecules (SCM add_molecules, int imol). merge molecules More.. cis_peptides (int imol). return cis_peptide info for imol.
  48. Moments of Genius: Nobel laureate Venki Ramakrishnan describes how…

    https://www2.mrc-lmb.cam.ac.uk/moments-of-genius-nobel-laureate-venki-ramakrishnan-describes-how-james-watson-discovered-dna-base-pairing/
    Thumbnail for Moments of Genius: Nobel laureate Venki Ramakrishnan describes how James Watson discovered DNA base pairing - MRC Laboratory of Molecular Biology 6 Dec 2010: Search this website. Moments of Genius: Nobel laureate Venki Ramakrishnan describes how James Watson discovered DNA base pairing. ... Moments of Genius: Nobel laureate Venki Ramakrishnan describes how James Watson discovered DNA base pairing.
  49. https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/28

    https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/28
    Isaac Asimov introduces James Watson and Francis Crick in the story of the structure of DNA, 8 July 1974. ... content/uploads/james_watson-33x50.jpg 33w" sizes="(max-width: 130px) 100vw, 130px" //pnulnliDiscovering the double helix.
  50. Blue Sky Collaboration - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/research/blue-sky-collaboration/
    Thumbnail for Blue Sky Collaboration - MRC Laboratory of Molecular Biology 10 Jan 2024: Stangherlin, A., Watson, J.L., Wong, D.C.S., Barbiero, S., Zeng, A., Seinkmane, E., Peak Chew, S., Beale, A.D., Hayter, E.A., Guna, A., Inglis, A.J., Putker, M.,
  51. Francis Crick (1916 - 2004) - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/alumni/francis-crick-1916-2004/
    Thumbnail for Francis Crick (1916 - 2004) - MRC Laboratory of Molecular Biology 30 Mar 2021: He will be best remembered for DNA, whose structure he discovered with Jim Watson in 1953.

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