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PPL number: | Granted: 10 Jun 19 | Amended: ...
https://www.ubs.admin.cam.ac.uk/system/files/public/provision_of_an_outsourced_drug_discovery_platform_for_diseases_with_an_inflammatory_component_nts_expires2022_redacted.pdf13 Sep 2021: disease. For example we breed mice that have been genetically modified as a model of lupus. ... These mice spontaneously develop antibodies to their own tissues in the same way as humans with lupus do but they appear outwardly normal. -
PK and PKPD studies to support Respiratory and Immunology research
https://www.ubs.admin.cam.ac.uk/system/files/public/pk_and_pkpd_studies_to_support_respiratory_and_immunology_research_non-technical_summary_redacted.pdf30 Apr 2024: COPD), arthritis and lupus. -
Discovery and development of treatments for immunological diseases
https://www.ubs.admin.cam.ac.uk/system/files/public/discovery_and_development_of_treatments_for_immunological_diseases_non-technical_summary_redacted.pdf29 Apr 2024: Why is it important to undertake this work? Despite decades of research, millions of people live with serious immune mediated disease such as colitis, arthritis, systemic lupus erythematosus (SLE) and atopic ... Other autoimmune diseases such as lupus -
Breeding and maintenance of rodents for drug discovery platform
https://www.ubs.admin.cam.ac.uk/system/files/public/breeding_and_maintenance_of_rodents_for_drug_discovery_platform_non-technical_summary_redacted.pdf29 Apr 2024: Examples of past/ongoing refinements:. NZM mice, a model for a disease that causes inflamed joints and skin (lupus), can start to have symptoms from 4 months of age.
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