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1 Dec 2019: Circ Genom Precis Med. 2019;12:e002507. DOI: 10.1161/CIRCGEN.119.002507 September 2019 397. BACKGROUND: Pediatric cardiomyopathies are a clinically and genetically heterogeneous group of heart muscle disorders associated with high morbidity and

18 Apr 2006: levels, is that overexpression of exogenous Tsg101 se-. questers endogenous Tsg101 binding partners (Vps28. ... Tal, a Tsg101-spe-. cific E3 ubiquitin ligase, regulates receptor endocytosis and retrovirus.

16 May 2008: derived from a retrovirus. Syncytins function in cell–cell fusion during trophoblast formation. Immunoglobulin (Ig)-like

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25 Jun 2007: Myc-EpsinR WT with endogenous AP1 and transferrin uptake in COS cells. ... Endogenous epsinR and overexpressed epsinR do not overlap with overexpressed epsin1 (see link), but there is considerable overlap with TGN markers (see below).

21 Jul 2023: Generation and live imaging of an endogenous Cdx2 reporter mouse line..

25 Jun 2007: Colocalisation of the wild type epsin (green) with endogenous clathrin (X22), Eps15 (Ra15), dynamin (McNiven antibody) and AP1 (100.3).

25 Apr 2019: These are endogenous daily rhythms that occur in every cell of the body; affecting a wide range of physiological processes, from when we sleep, to hormone levels, to how quickly we

31 May 2024: https://www2.mrc-lmb.cam.ac.uk/news-events/public-engagement/ One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the molecular level - providing the knowledge needed to

21 Jul 2023: chemotherapeutic drugs and alcohol, or endogenous by-products of normal cellular metabolism.

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25 Jun 2007: Myc-EpsinR L10E with endogenous AP1 and internalised transferrin in COS cells.

26 Sep 2011: For a detailed study of endogenous epsinR and overexpression of wild-type and mutants in cells see immunocytochemistry.

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3 May 2002: This might be caused bycompetition for clathrin binding between the injectedpeptide and the endogenous protein, therebypreventing endogenous AP180 and AP2 frompromoting clathrin assembly at the plasmamembrane.

mrc-lmb.cam.ac.uk/wordpress/wp-content/uploads/Leo-James-HIV-Nature-cover-28-July-16.jpg 700 700 HIV is a retrovirus, meaning it has to copy its RNA

20 Sep 2004: Cells separatedsister chromatids with identical kinetics to those thatof the GAL1-10 promoter in cells with an endogenous. ... Nevertheless, noncleavableScc1-HA3 from the endogenous SCC1 promoter. The. sole copy of Cdc20 in all three strains was

4 Aug 2017: Catalytically inactive UBE2O(C1040S) alsorecovered endogenous and exogenous RPL24(but no detectable ubiquitinated forms), whereasUBE2O(DCR2) interacted poorly with RPL24 (fig.S10D). ... The heterogeneity of ubiquitin bands in the samples with cytosol is

19 Mar 2013: Amph12 RNAi) depletion on the recruitment of endogenous dynamin 2 (dynaminen, green and white arrows) and clathrin light chain A (clathrinen, red). ... Bar, 10µm (B) Effect of SNX9, amphiphysin and endophilin overexpression on endogenous dynamin 2

26 Sep 2011: Myc-EpsinR with endogenous TGN46 and AP1 in COS cells. In the image to the left there are 2 cells transfected with Myc-epsinR and 3 cells not transfected. ... In the left cells endogenous AP1 is finely punctate and co-localises with the more tubular

18 Sep 2008: Ifn-PrP. Note the lack of changes to endogenous PrP in cells expressing. ... Thus, in both cases, Ifn-PrP is not being overexpressed relative. to endogenous PrP.

18 Jan 2019: SQS insertion by EMC enables sterol biosynthesisTo determine the mechanism responsible for downregulating SQSin EMC-knockout cells, we monitored endogenous SQS synthesisand turnover by performing 35S-Met/Cys pulse-chase assays. ... A) 35S-Met/Cys

25 Jun 2007: Endogenous epsinR with Myc-epsin1 and Myc-epsinR. Endogenous EpsinR. ... Endogenous EpsinR. Overexpressed. Myc-EpsinR. Endogenous epsinR expression.

21 Mar 2003: The most likely explanation for this is that theinteraction of dynamin with endogenous amphiphysin wasdisrupted in these cells. ... J Cell Biol 1993, 127:725-735. 18. Tuma PL, Stachniak MC, Collins CA: Activation of dynamin GTPaseby acidic phospholipids

3 Sep 2014: coli ETEC H10407 was investigated. The protein at endogenous expression levels is easilydetected and this signal disappears in a leoA KO strain, demonstrating specificity.

30 Jun 2015: Under these conditions, we only observed endogenous acetylcholine EPSCs. To recordGABAergic postsynaptic currents, the holding potential was 0 mV, at which we only observemIPSCs. ... Supporting InformationS1 Fig. Stimulus-evoked EPSCs and endogenous

4 Jan 2006: various endophilins and controls. a. b. c. Transformation of JC201 bacteria with endophilin does not lead to an acceleration of growth kinetics, unlike transformation of the endogenous LPAAT.

10 Nov 2000: 1B), despitethe fact that endogenous Vg1 was expressed only in the late-stageoocytes (Fig. ... 1C). This result raisesthe possibility that the endogenous, localized Vg1 message is inan environment that is free from repression.

27 Nov 2003: Immunofluorescence microscopy of endogenous Mbl in fixed cells gave. similar images.

28 Nov 2008: G) Epifluorescence micrographs of a HeLa cell incubated with CTxB for 5 min before fixation and staining for endogenous GRAF1. ... B, Confocal micrograph of an NIH 3T3 cell stained for endogenous GRAF1 distribution.

4 Mar 2008: As shown in Fig. 5, WTFtsQ expressed together with sYFP1-FtsL in LMC531cells (that contain the endogenous temperature-sensitivemutation E125K) target FtsL to midcell at both 28C and42C (Fig. ... The resulting strains wereconfirmed by PCR analysis,

2 Jun 2004: 1B).BAPGRA4 was localized to dense granules as evidenced bycolocalization with the endogenous dense granule proteinGRA3 (32). ... Both endogenous GRA4 andBAPGRA4 were efficiently translocated across the ER mem-brane (Fig.

23 Jul 2007: performed dual immunofluorescence staining of expressed. KIF16B-PX and endogenous EEA1 using fixed HEK293 cells. ... In agreement with A431 cell localization, KIF16B-PX was. colocalized with endogenous EEA1 (Figure 6A).

14 Nov 2021: the ATP-dependent Lon protease- lessons from. endogenous protein and synthetic peptide substrates.

18 Feb 1999: Such molecules mightmimic an endogenous cellular factor, presumably a lesspotent one, that helps to stabilise microtubules in normalcytoplasm; the natural reagent might be a small molecule orpart of a microtubule-associated

1 Nov 2004: InhVps37A and hVps37B (Bache et al., 2004; Stuchell et al.,addition, they play a critical role in retrovirus budding.2004), while the human ESCRT-II subunits correspondStructural understanding of ESCRT interaction ... The CCP4 suite: Morita, E., and

6 Dec 2014: Unfortunately, it is currently not possible to reliablyimage at endogenous levels of MinC with SIM.

21 Nov 2012: Depletion of endogenous MITD1with two independent small interfering RNAs (siRNAs) resultedin phenotypes consistent with cytokinesis failure, as indicated bya six- to eightfold increase of multinucleated cells compared withcontrol siRNA-transfected

23 Dec 2013: coli cells, we constructed C-terminal fusions of the fluorescentprotein YPet to wild-type FtsK and truncated derivatives of it ex-pressed from the endogenous wild-type chromosomal locus.

15 May 2007: colocalizing with endogenous AP-2 complexes (Figure 2. G–J). In contrast, the IVA mutation resulted in complete. ... plasma membrane (Figure 5A), which colocalized with both. clathrin–DsRed and endogenous AP-2 complexes (Figure 5.

3 Dec 2004: endogenous AP2 (middle, AP6 antibody) and transferrin uptake (right). A strong.

15 Oct 2007: A) Endogenous p150 co-immunopre-cipitates with tau in differentiated SH-SY5Y cells. Immunoprecipitation was performed with anti-tau antibody BR133 and immunoblots withp150 antibody. ... transgenic mice (data not shown) has been hampered by a. likely

31 Jan 2020: rTG appears to be indistinguishable by sodium dodecyl sulfate–polyacrylamide gel electrophoresis (SDS–PAGE) and cryo-electron microscopy (cryo-EM) from endogenous TG (eTG) puri-fied from thyroid glands of patients

23 May 2012: IB, immunoblot-. ting. (B and C) Endogenous interactions between the. Bag6 and the gp78-p97 complexes. ... Trc35 Maintains a Cytosolic Pool of Bag6(A) Trc35 expression alters the subcellular localization of endogenous Bag6.

27 Mar 2012: away from the nucleotide-binding site of FtsA (Figure 2A,. right), which contains an endogenous ATP molecule at. ... appearance that is straightforward to distinguish and. quantify. We then complemented the endogenous ts-FtsA.

6 Jun 2014: elifesciences.org. van den Ent et al. eLife 2014;3:e02634. DOI: 10.7554/eLife.02634 1 of 22. Bacterial actin MreB forms antiparallel double filamentsFusinita van den Ent1†, Thierry Izoré1†, Tanmay AM Bharat1, Christopher M Johnson2, Jan Löwe1.

30 Jul 2013: inherent flexibility of the tubes and other factors, such as heterogeneity of the endogenous.

27 Apr 2009: However, the endocytosisof many other types of endogenous and exoge-nous cargoes is relatively unaffected by inhibi-tion of this pathway. ... Relatively few endogenous, noncargo pro-teins associated with clathrin-independent. endocytic pathways have been