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14 Aug 2023: Combining the latest science with the traditional knowledge of local communities, these projects work to reverse habitat loss, restore ecosystems and improve people’s well-being. ... increasing sense that, over coming years, conservation and synthetic

14 Aug 2023: 17. 4: Pathway Engineering – Bug Sweatshops. 19. 5: Expanding Earth’s Genetic System – Alien Genetics. ... 4. Pathway Engineering – Bug Sweatshops. 5. Expanding Earth’s Genetic System – Alien Genetics.

14 Aug 2023: How people determine whether something is alive and whether micro-organisms are seen to be alive. • ... How and if people view this technology as different to that of ‘GM’ and why.

14 Aug 2023: PRO. JECT. REP. ORT. EU. R 2. 1796. Synthetic BiologyApplying Engineering to Biology. Report of a NEST High-Level Expert Group. Interested in European research? RTD info is our quarterly magazine keeping you in touch with main developments (results,

14 Aug 2023: For Kew collected material, Kew checks that, before going into the field, people have done their paperwork and have the necessary permits for collecting. ... They want to avoid people moving away from certain areas of research or from working with

14 Aug 2023: The authors acknowledge the many people that made this workshop possible.

14 Aug 2023: Sugarcane cultivation is a major driver of deforestation and land degradation, as well as being an industry notorious for violent displacement of people from their lands, and slave labor conditions.57.

14 Aug 2023: The discovery of penicillin by Alexander Fleming in 1928 saved the lives of countless people battling with the number one cause of death in the last centur y – bacterial infections. ... And the Green Revolution, a synonym for advances in the

14 Aug 2023: Prof Jim Haseloff. Head of the lab, with a history of research in plant viroids, RNA enzymes and engineering approaches to plant development. Current interests are in simple open systems for engineering plant growth. Dr Facundo Romani. Facundo is an

14 Aug 2023: Engineering plant growth. Synthetic Biology is an emerging field that employs engineering principles for constructing genetic systems. The approach is based on the use of well characterised and reusable components, and numerical models for the

14 Aug 2023: http://haseloff.plantsci.cam.ac.uk (note: these pages are suitable for direct printing) Jim Haseloff, University of Cambridge.

14 Aug 2023: Teaching resources for courses on plant development and biotechnology. These pages contain information for a variety of different courses on plant development and biotechnology that are provided by Jim Haseloff at the University of Cambridge. They

14 Aug 2023: Cross-section of the Marchantia polymorpha thallus. Photosynthetic cells are enclosed within chambers below the upper epidermal surface of the thallus. Specialised cells form an air pore to facilitate gas exchange and limit water loss. The lower

14 Aug 2023: Resources to support work with plant systems. This section of the website contains links to various local resources that we have developed. Hopefully some may be directly useful, others for survey or to trigger plant-inspired ideas. OpenPlant is a

14 Aug 2023: Outreach activities. We play a major role in promoting accessible technologies for interdisciplinary activities, bringing biologists together with engineers, physical scientists and social scientists. These activities range from student-led

14 Aug 2023: Marchantia polymorpha. The liverworts (or Marchantiophyta) are descendants of the earliest terrestrial plants. The group is characterised by morphological simplicity, and this seems to be matched by simple underlying genome structures. Liverworts

14 Aug 2023: Liverwort hunting at the XIIIth Australian Bryophyte Workshop—Flinders Ranges and Adelaide, South Australia. The workshop was held near Quorn in the Flinders Ranges, in August 2016 and was followed by identification sessions and expert workshops

14 Aug 2023: Biology will never be the same. The remarkable scientific success of biology in describing, explaining, and manipulating natural systems is so well recognized as to be a cliche—but the engineering application of that scientific knowledge is just

14 Aug 2023: Growth in soil. Marchantia polymorpha is a weed, and the plants are very easy to grow. We have experimented with a number of media and growth conditions. For very vigorous growth, we have used jiffy-7 pots, which are supplied as compressed dried peat

14 Aug 2023: Marchantia polymorpha has 9 chromosomes and a genome size of around 290MB. The dominant form is the haploid gametophyte. The plant is dioecious, with sex determined by segregating X and Y chromosomes. The Y chromosome has been sequenced recently

14 Aug 2023: Your Album (Click to Change). http://haseloff.plantsci.cam.ac.uk (note: these pages are suitable for direct printing) Jim Haseloff, University of Cambridge.

14 Aug 2023: http://haseloff.plantsci.cam.ac.uk (note: these pages are suitable for direct printing) Jim Haseloff, University of Cambridge.

14 Aug 2023: Genomics, Epigenetics & Synthetic Biology. Part II Plant Sciences Module L1. Synthetic Biology: Prof. Jim Haseloff. Supplementary material:. Click here to find relevant papers as downloadable PDFs. Click here to find sample essay questions. Click

14 Aug 2023: Microscopy of GFP-expressing plant tissues. The major advantage of GFP is that it is intrinsically fluorescent, and the protein is be directly visible in living tissues where it is being expressed. There are many benefits to working with live samples

14 Aug 2023: Macrophotography in the field. The documentation of liverworts in the field, growth room or laboratory can be a challenge. The small size of the plants means that plant features may need to be captured at sub-millimetre, almost cellular scales.

14 Aug 2023: Cambridge team for the iGEM2012 Synthetic Biology competition. Cambridge iGEM2012 team project. iGEM teams have characterised an array of biosensor components, but outputs are often inconsistent and, despite common assembly standards, it remains

14 Aug 2023: Synthetic Biology Explained: Bridge8. Synthetic Biology: Overview - Victor de Lorenzo. Early Synthetic Biology talk: Tom Knight. E.O. Wilson: Synthetic Biology Will Radically Change the World. Jim Haseloff, University of Cambridge.

14 Aug 2023: Plant and microbial microscopy and visualisation. The last twenty years have seen a revolution in the application of optical techniques to the study of biological systems. This largely due to the development of highly specific fluorescent labelling

14 Aug 2023: The student team. Each year we recruit 6-12 undergraduate students to participate in the iGEM competition. The students work as an interdisciplinary team to construct an engineered biological system from DNA components, including design and

14 Aug 2023: Cambridge iGEM2011 Bactiridescence project. Inventive constructions using BioBricks. Bioluminescence and the science of Christmas. Glowing trees could light up city streets. How 'bioluminescent' trees that glow like fireflies could one day replace

14 Aug 2023: Plant Synthetic Biology. University of Cambridge, Plant Sciences Part II. Discuss the relative benefits and difficulties of genetically reprogramming metabolism in algae versus plants. Describe recent advances in the assembly of synthetic DNAs. What

14 Aug 2023: Plant Visions 1904-2004. An exhibition of images to celebrate the centenary of the opening of the Plant Sciences laboratories in 1904. Curated by Beverley Glover (website) and Jim Haseloff. Click here to view the exhibit. Download a copy of the

14 Aug 2023: 3D visualisation. Individual cells can be segmented using confocal datasets and rendered in three dimensions. Whole tissues can be reconstructed from the component cells - as shown here for a root meristem within an Arabidopsis embryo. Outer cells

14 Aug 2023: Abstract: Malaria is a global health problem that threatens 300-500 million people and kills more than one million people annually.

14 Aug 2023: Crystals, microbes and plants. Fernán Federici & Jim Haseloff. “What are the roots that clutch, what branches grow. Out of this stony rubbish?”. TS Eliot, The Waste Land. Part of a pioneering new exhibition, ‘April is the Cruellest Month.’

14 Aug 2023: Synthetic Genomics. A series of papers has been published in Science (10th March 2017), which provide a picture of current progress to resynthesise the entire genome of Saccharomyces cerevisiae - the SC2.0 project (). Four of these papers have been

14 Aug 2023: Vanguard Alta Pro 2+ 263AT with GH-100 pistol grip ball & socket head. For high resolution and/or time-lapse work with small plants like liverworts, a camera support is very useful…even essential. The camera support of course needs to be stable,

14 Aug 2023: Mk I Handheld Macroscope (Spring 2017). Original setup for high resolution handheld macrophotography. 1. Panasonic Lumix GX80 camera with 16 megapixel 4/3" sensor, image stabilisation, 4K video, focus bracketing and image stacking. 2. Neewer 10mm

14 Aug 2023: Weatherproof cameras for field documentation. Comparison of Olympus TG-4 and TG-5 cameras for handheld collection of extended focus macrographs. The TG-4 is an extremely robust point-and-shoot camera that can be equipped with an LED illuminator (LG-1

14 Aug 2023: The wild type Aequorea victoria green fluorescent protein mRNA is mis-spliced in Arabidopsis thaliana. GFP sequences were amplified from DNA or mRNA isolated from transgenic Arabidopsis thaliana C24 plantlets. Radiolabelled products were then mapped

14 Aug 2023: GFP background. Aequorea victoria are brightly luminescent jellyfish, with glowing points around the margin of the umbrella. Light arises from yellow tissue masses that each consist of about 6000-7000 photogenic cells. The cytoplasm of these cells

14 Aug 2023: Maturation of green fluorescent protein. The post-translational maturation of GFP to the fluorescent form involves a number of steps. In the first step, the GFP apoprotein presumably must fold into a catalytically active conformation that

14 Aug 2023: Jim Haseloff. email: jh295(at)cam.ac.uk. Haseloff Lab. Department of Plant Sciences. University of Cambridge. Downing Street. Cambridge CB2 3EA. United Kingdom. tel: 44-1223-766546. swb: 44-1223-333900. web: http://haseloff.plantsci.cam.ac.uk.

14 Aug 2023: Manuel Waller, Eftychios Frangedakis, Alan O Marron, Susanna Sauret-Gueto, Jenna Rever, Cyrus Raja Rubenstein Sabbagh, Julian M Hibberd, Jim Haseloff, Karen Renzaglia, Péter Szövényi. Plant Journal, doi: 10.1111/tpj.16161. 2023. Land plants

14 Aug 2023: Research projects in the Haseloff Laboratory. Synthetic Biology is an emerging field that employs engineering principles to construct new genetic systems. The approach is based on the use of well characterised and reusable DNA components, and

14 Aug 2023: Part 1B Cellular & Developmental Biology. Plant Development. Prof. Jim Haseloff, University of Cambridge. Summary:. These four lectures cover some striking features of biological self-organisation and morphogenesis using examples from the model plant

14 Aug 2023: Cambridge-JIC teams in the international Genetically Engineered Machine (iGEM) competition. iGEM is an international undergraduate synthetic biology competition where student teams are given access to DNA parts from the Registry of Standard

14 Aug 2023: iGEM2010 project: E. glowli. The Cambridge iGEM2010 team worked on regeneration systems for bioluminescence and better, brighter light output, different coloured luciferases, instrumentation for quantitation and modelling the feasibility of using

14 Aug 2023: The liverworts (or Marchantiophyta) are descendants of the earliest terrestrial plants. The group is characterised by morphological simplicity, and this is matched by simple underlying genome structures. Many lower plants, including liverworts,

14 Aug 2023: iGEM2009 project: E. chromi. The Cambridge iGEM2009 team created two kits of parts to facilitate the design and construction of biosensors in the the future. These complement genetically engineered bacterial biosensors that enable bacteria to